Dicotyledonous, Gamopetalous.
Jerome Beers Thomas translation
Rubiaceæ.
Madder Family.
Hymenodictyon excelsum, Wall. (H. Horsfieldii, Miq.; Chinchona excelsa, Roxb.; Exostema Philippicum, Blanco.)
Nom. Vulg.—Huligaga, Tag.
Uses.—The bark of this tree has a wide reputation in India as a tonic and febrifuge. The inner layer of the bark possesses astringent and bitter properties much like quinine. Ainslie states that it is used in India to tan hides and therapeutically where an astringent is required. O’Shaughnessy experimented with it in the hospital of the Medical College of Calcutta and reported good tonic and antipyretic effects.
In 1870, according to Dymock, Broughton analyzed the fresh bark and reported that the bitter taste was due to esculin, which after drying and coming in contact with decomposing organic matter is transformed into the almost tasteless esculetin. Naylor studied the bark at a later period, and attributed the bitterness to an alkaloid that he named hymenodictyonine. This substance exists in the form of a gelatinous mass, cream-colored, very hygroscopic. An ethereal solution, carefully evaporated, deposits it in the form of crystals. Its empirical form is C23H40N2; it is probably volatile and is notable for its lack of oxygen. It differs from quinoidine in that it is inactive (?) and that in combination with platinum it retains less of this metal than does quinoidine. It differs from paricine in its proportion of hydrogen, and from berberine in containing more carbon. In the presence of sulphuric acid its solution assumes a yellow color, changing to wine-red and then to dark red. Naylor extracted another principle which he found combined with the alkaloid in a soda precipitate of the latter; it is a product of the decomposition of a glucose, the formula of which is C25H49O7. This compound remains insoluble when the alkaloid is treated with ether. Repeated boiling in alcohol renders it colorless. It is bitter, soluble in alcohol and dilute acids; insoluble in ether and chloroform. Reaction, neutral.
Botanical Description.—A large tree, with leaves opposite, oval, entire, acute, downy. Petioles long, flat above, with 2 stipules. Flowers axillary, in compound verticillate racemes. Calyx adherent, with 5 promptly deciduous teeth which leave a scar that also disappears. Corolla much longer than the calyx, funnel-form, the limb 5-cleft. Stamens 5, inserted near the middle of the tube. Filaments rudimentary. Anthers 2-celled. Style longer than the corolla. Stigma globose. Seed-vessel rather rough, ovoid, flattened, of 2 compartments, where are inserted numerous seeds, imbricated, circular, encircled by an entire wing.
Habitat.—Angat and the woods of San Mateo. Blooms in August. (P. Blanco states further that this tree grows to a height of about 3 yards in Angat and that it exhales a strong odor resembling that of vinegar at times, and again like that of tobacco.)
Oldenlandia corymbosa, L. (O. biflora, Lam.; O. ramosa, Roxb.; O. herbacea and serabrida, DC.; O. burmaniana, Mig.)
Nom. Vulg.—Doubtful.
Uses.—The Sanscrit writers often mention this plant as an important remedy for the fevers due, according to their theories, to disordered bile, i. e., remittent fevers, accompanied by gastric irritability and nervous depression. The entire plant is used to make a decoction, often combined with aromatics. Dymock observed in Goa that this plant could be gotten in all the shops of the herb-venders, and that it was widely used as an alterative in mild fevers in combination with “Hydrocotyle Asiatica and Adiantum lunulatum.”
In Concan they apply the juice to the hands and feet in fevers, giving at the same time a dose of one “tola” (6.80 grams) in sweetened water or milk. This juice is obtained by soaking the bruised plant in water. In remittent fever the decoction is also used as a liniment for the whole body. It is given internally for skin eruptions due to excessive heat, especially “lichen tropicus.”
Botanical Description.—A small herb, stem straight, about 30 centimeters high, glabrous, dichotomous. Leaves opposite, linear, green, lanceolate, stipulate. Flowers small, hermaphrodite, axillary, solitary, or in pairs, alternate or opposite. Calyx gamosepalous with 5 short teeth. Corolla gamopetalous, funnel-shaped. Stamens 5, free, inserted in the tube of the corolla. Ovary inserted in the hollow of the receptacle, 2 many-ovuled locules. Style simple, ending in a bifid stigma. Capsule rounded-oval, membranous. Seeds numerous, polyhedrous, albuminous, surface granular.
Habitat.—In the rice fields.
Randia dumetorum, Lam. (R. longispina, DC.; R. aculata, Blanco; R. stipulosa, Miq.; Gardenia spinosa, Blanco.)
Nom. Vulg.—Sinampaga, Tag.
Uses.—The fruit is used in some parts of India to kill the fish in ponds and sluggish rivers, the same use to which they sometimes put the “Cocculus Indicus.” It is prescribed as an emetic by the Sanscrit and Arabic medical authors of India. Mooden Sheriff ascribes its emetic properties to the pulp alone, the epicarp and seeds being inactive according to his authority. It is a substitute for ipecac even in the treatment of dysentery in which case the decoction of the trunk bark is also used.
The dried and powdered pulp is given in dose of 2.50 grams as an emetic and 1–2 grams as an antidysenteric. To prepare the fresh fruit for administration as an emetic, mash 2–3, macerate 15 minutes in 150–200 grams of water and filter. It acts in a few minutes and its effect may be hastened by giving tepid water or tickling the fauces.
Botanical Description.—A shrub with straight, thorny stem, leaves sessile, springing from the buds, occurring in threes, obtusely lanceolate, entire, glabrous. Flowers solitary or in pairs, very fragrant. Calyx gamosepalous with 10 toothlets. Corolla twisted, arched, cleft in the middle, throat nude, limb slashed in 5 large glabrous parts. Stamens 5. Filaments short, inserted on corolla. Style 1. Stigma bifid. Fruit inferior, about the size of a crab apple, crowned by the remains of the calyx, smooth, yellow, fleshy, 1-celled with many seeds.
Habitat.—On the coast of Luzon. Blooms in May.
Ixora coccinea, L. (I. bandhuca, Roxb.)
Nom. Vulg.—Santan, Tag.
Uses.—The handsome red flowers are used in decoction for hæmoptysis and catarrhal bronchitis. Both root and flower are astringent and are given for dysentery. In Concan they cook 2 “tolas” (13.60 grams) of the flowers in lard, together with coriander and “mesua ferrea,” add a little candied sugar and divide the mass into large pills to be given twice a day.
The fresh root in the form of an alcoholic tincture has been recommended by Deb for dysentery, the dose 2–4 grams in an appropriate potion. The tincture of the fresh plant is prepared by macerating 126 grams of the fresh root 15 days in 473 grams alcohol. The plant has been used in intermittent fevers and various skin diseases.
Botanical Description.—A shrub cultivated in all gardens, 6–8° high. Leaves oval, entire, glabrous. Flowers in terminal umbels, white, pink or red. Corolla tubular with limb cleft in 4 rounded lobes. The plant is so well known that further description would be superfluous.
Coffea Arabica, L.
Nom. Vulg.—Cafe, Sp.; Coffee, Eng.
Uses.—The infusion of roasted and ground coffee seeds constitutes a beverage of Arabic origin, but now common all over the world. In the Philippines, where a few years ago the coffee plant was only cultivated in gardens, the harvest has assumed such proportions that it now constitutes one of the greatest sources of agricultural wealth. Its use is becoming more general every day and the discovery of its alkaloid “caffeine” the therapeutical use of which is also steadily increasing, has given new importance to the seed on account of its increasing demand in the drug trade. When newly harvested its taste is not very agreeable, for it needs considerable time—2 or 3 years—in which to dry completely, before it acquires the aromatic properties and the savor of which it is susceptible. General Morin relates an incident of having drunk a delicious infusion of coffee made from authentic Moka that had been kept for fifty years, of course under ideal conditions of preservation.
In civilized countries coffee is an article of prime necessity as a food; here we shall consider it therapeutically under two heads, as a tonic-stimulant and as an antiseptic. As caffeine is the principle that acts upon the heart we shall consider the cardiac properties of coffee under the head of that alkaloid, so important that it may best be studied separately.
There are two preparations of coffee, the decoction used by the Arabs and the infusion, used in Europe and adopted in the Philippines. The decoction forms a tonic and aromatic drink devoid of any excitant properties, but the infusion is highly excitant and should not be taken in such large amounts as the decoction, for its action may be powerful enough to cause headache, nausea, trembling of the extremities and disorders of vision and hearing. These phenomena however are not dangerous and rapidly subside as soon as the urine eliminates the substances that cause them.
Infusion of coffee stimulates especially the cerebral functions and the circulation; as to its digestive properties, opinion is divided but it is more probable that it lacks them and that coffee taken after meals owes its reputation as a digestive aid to two distinct factors—the temperature and the sugar. Without doubt it exerts an anaphrodisiac action, on account of which the illustrious Linnæus called it the “drink of eunuchs.” This action seems incompatible with the fact that the Arabs, who are so much given to the abuse of the pleasures forbidden to eunuchs are most addicted to the use and abuse of coffee. The explanation rests in the form in which they consume their coffee, namely the decoction, which is free from the sedative principle of the seed, that undoubtedly resides in the aromatic ingredient “cafeol.”
Coffee is contraindicated in hysterical and nervous persons, in children and in those who suffer with insomnia or palpitation. It counteracts sleep and coma, being very useful in poisoning by opium or its alkaloids. Its stimulant action is as rapid as that of alcohol. On several occasions it has yielded me marked results when given by stomach or by enema in cases of nervous and cardiac depression. Indeed it is a remedy that I cannot recommend too highly and each day leaves me more convinced of its therapeutic activity and certainty.
Attention has only lately been directed to the antiseptic property of coffee though we have long been availing ourselves of that property without knowing it; this is true of many other medicinal agents, indeed of all that the modern studies of bacteriology have presented to us as antifermentives and microbicides. Roasted coffee in powder form gives good results if dusted over ulcers and gangrenous sores, rapidly improving their appearance and destroying the fœtid odor. It corrects the unhygienic properties of non-potable water and therefore enters into the army and navy ration of nearly all the nations of Europe. In epidemics of disease every physician should advise its use in mild infusion as a regular beverage.
Dr. Luderitz, experimenting in the Hygienic Institute of Berlin, reported that no bacteria could resist the action of coffee in infusion. He attributed this action not only to the tannin, which is present in high percentage, but principally to the empyreumatic substances formed by the roasting. The caffeine takes no part in this action. Dr. Luderitz exposed the coffee to the open air for six days and found it free from bacteria at the end of that time. Whatever may be the explanation of its activity the fact remains that coffee is highly antiseptic, and this should be kept in mind by physicians not only because it is everywhere easily obtained and an infusion easily prepared, but because it in addition possesses the great advantage of being nontoxic.
The chemical analysis of the seed is as follows:
Cellulose 34.000
Water 12.000
Fatty matters 10 to 13.000
Glucose, dextrin, undetermined acid 15.500
Legumin, caffeine 10.000
Chlorogenate of caffeine and potassa 3.500 to 5.000
Albuminoids 3.000
Caffeine, free .800
Essential oil, solid .001
Essential oil, liquid .002
Mineral substances 6.697
Caffeine, the only one of the ingredients that interests us, was discovered by Hunge in 1821 and recognized as an alkaloid by Herzog. It also exists in tea, formerly known as “theine” which is now known to be identical with caffeine; both are expressed by the formula C8H10N2O2+H2O. It crystallizes in fine, silky needles, is colorless, odorless and slightly bitter.
It is considered a substitute for digitalis, especially valuable as a diuretic and where cerebral anemia exists. Germain See values it as a preventive medicine, acting principally upon the heart and thus preventing fatigue; with this end in view he advises its use before long marches, violent exercise and all conditions where the heart will be called upon to do a greatly increased amount of work. Dose 0.25 gram to 1 or 2 grams a day given by stomach or hypodermic injection.
Caffeine is also useful in headache, neuralgia, and asthma and as a general tonic. For the latter action it is best given in pill form, 0.02–0.04 gram a day, with the extract of cinchona or other bitter tonic.
“Etoxy-caffeine,” which is caffeine in which an atom of H has been replaced by the C2H5O, exists as white, needle-like crystals, slightly soluble in water; it is narcotic and sedative to the cerebro-spinal system. In doses of 0.24 gram it is useful in headache.
Botanical Description.—“A small tree that reaches a height of 8–9°. It grows readily in the province of Batangas without cultivation,” Blanco.
A small tree or shrub with leaves opposite, smooth, glossy, rich green, oval, edges fluted. Flowers fragrant, white, growing in small clusters in the axils of the leaves. Calyx 4–5-toothed. Corolla short-tubed with 4–5 spreading lobes of about the same length. Berry red, containing two plano-convex seeds enveloped in arils.
The plant is widely cultivated in gardens. It finds ideal conditions for growth in some of the hilly and mountainous regions of Luzon, notably in Benguet and Batangas.
Morinda citrifolia, L.; variety: bracteata, Hoock, Jr. (M. ligulata, Blanco.)
Nom. Vulg.—Bankundo, Pankundo, Bag̃kuro, Nino, Kulit, Tumbog̃aso, Lino, Mambog, Takpus, Tag. and Vis.; Taliantar, Pam.; Apalot, Iloc.; Indian Mulberry, Indo-Eng.
Uses.—In the Philippines, as well as in India, the root of the plant is widely used as a red dye. As a medicine the Tamul physicians use it in decoction to treat diarrhœa and dysentery. The fruit is emmenagogue and perhaps aperient. In Bombay the mashed leaves are applied to wounds and ulcers to hasten cicatrization; they also use the decoction internally as a febrifuge and tonic, 10 grams to 500 of water, a wineglassful twice a day.
The root bark contains a crystalline substance called by Anderson morindin, C28H30O15. It is a glucoside and exists in the form of yellow needles, soluble in alcohol and in cold water, insoluble in ether; dissolves in alkalies producing an orange-red color.
There is another species, M. tinctoria, Roxb.; M. Royoc, Blanco, called in Tagalog Tumboug̃ aso kapay, the roots of which are used by the Filipinos for the same purposes as the leaves of the former species; the dose, 8 grams a day. The powder is also applied to ulcers and sores, especially those of gangrenous aspect.
Botanical Description.—A small tree 11 or more feet high, branches opposite, quadrate at the extremities. Leaves opposite, oval, oblong, smooth, entire, glabrous. Petioles very short, with 2 broad, lanceolate stipules curved outward. Flowers white, opposite the leaves, fixed on globose, solitary receptacles from which spring the flowerets. Calyx proper, very short, monophyllous, a lanceolate leaflet springing from the border. Corolla tubular, woolly inside about the middle, with 5 lobules. Stamens 5, inserted on the walls of the corolla. Anthers thin, incumbent. Pistil somewhat longer than the corolla. Stigma cleft in 2 laminæ. Fruit: the receptacle of the flowerets ripens to a globe bristling with the remains of the calyces, like a berry covered with many smaller ones, each containing 2 monospermous, quadrangular seeds.
M. tinctoria, Roxb., is a climbing shrub with leaves opposite, ovate, keeled; petioles very short; flower and fruit like the foregoing species.
Habitat.—In Luzon and, especially the M. tinctoria, in Malinta, Calauan and Tanauan.
Pæderia fœtida, L. (P. sessiflora, DC.)
Nom. Vulg.—Kantutan, Kantutæ, Tag.; Lilitan, Tæ-tæ, Vis.
Uses.—The fœtid odor of this plant has suggested both the technical and common names for it. The natives regard it as a cure for rheumatism. The root is emetic. The leaves, boiled and mashed, are applied to the abdomen in retention of urine; the decoction of the leaves is used for the same purpose and also has some reputation as a solvent for vesical calculus. For fever, cloths soaked in the decoction are applied to the head, the same preparation being given internally at the same time.
Botanical Description.—A slender, twining plant with leaves 3′ by 1′, opposite, oval, acute, entire, long petioles and caducous stipules. Flowers dark rose color, in compound axillary and terminal cymes. Calyx of 5 persistent lobules. Corolla tubular, pubescent, 5 lobules. Stamens 5, free. Ovary inferior, flattened, 2 uniovulate locules. Style with 2 stigma-bearing branches.
Habitat.—Luzon, Mindanao, Cebu, Panay.
Compositæ.
Eupatorium Ayapana, Vent.
Nom. Vulg.—Aya-pana, Sp.; Ayapana, Apana, Tag.; Ayapan, Indo-Eng.
Uses.—A native plant of Brazil now naturalized and well known in the Philippines and many other tropical countries; it is called by its Brazilian name, Aya-pana, more or less modified. The entire plant is aromatic and its infusion has an agreeable, bitter taste. Its virtues have been much exaggerated, but it is certainly a good stimulant, diaphoretic and tonic. An infusion, 30 grams of the leaves to 1 liter of water, is given in dyspepsia, a small cup after each meal. In the island of Mauritius this infusion was widely used as a stimulant and aromatic in the cholera epidemics of 1854 and 1856.
It is used internally and locally for the bites of venomous snakes and insects. The leaf-juice is a good application for foul ulcers, as is also the decoction of the entire plant. “It appears probable that this plant has fallen into unmerited neglect.”—Pharm. of India.
Botanical Description.—An aromatic plant 3° high, leaves opposite, sessile, coherent at the base, lanceolate, entire, glabrous. Flowers in racemose panicles. Common calyx cylindrical, of many imbricated, awl-shaped scales, the lower ones smaller; within are 20 or more hermaphrodite disk-flowers. Corollas are funnel-form, 5-lobed. Style a little longer than the stamens. Stigmas 2, long. Seed 1, quadrangular, with simple, downy, sessile pappus. Receptacle nude.
Habitat.—Common in fields and gardens. Blooms in January.
Blumea balsamifera, DC. (Conyza balsamifera, L.)
Nom. Vulg.—Sambon, Tag.; Lakbandulan, Hamlibon, Lalakdan, Lakadbulan, Gintingintin, Gabuen, Ayoban, Alibun, Vis.; Sobsob, Iloc.
Uses.—Sambon is a panacea among the Filipinos; its virtues are prodigious according to the ignorant natives who wear the leaves in the hat or the “salakod” (rain hat), to prevent “tabardillo” (“burning fever”; tabardillo pintado = spotted fever). They use the decoction to bathe convalescents, and for rheumatism they vaporize it in an improvised bath-cabinet consisting of a chair in which the patient sits enveloped in blankets that reach to the floor and retain the steam.
The hot infusion of the leaves is a good diaphoretic taken by the mouth, especially useful in catarrhal bronchitis, and prized as an expectorant by the Chinese and Javanese. Furthermore it is stomachic, antispasmodic and emmenagogue.
The camphorous odor of the plant suggested to me its application as an antiseptic lotion for varicose ulcers and my results have been very satisfactory. The infusion for internal use is 30 grams to the liter of water.
Botanical Description.—A woody plant 6–9° high. Leaves 1° long, 3′ wide, oblong, lanceolate, acutely serrate, rugose, soft, downy, whitish. Flowers yellow in panicles. Involucre conical, of many linear scales, enclosing 15 or more hermaphrodite disk-flowers and several pistillate ray-flowers. Hermaphrodite: corolla infundibuliform, 5-toothed. Pistillate: corolla very minute, infundibuliform, obscurely 4-toothed. One seed crowned with a simple hairy pappus.
Habitat.—Grows universally in the islands and is well known. Blooms in January.
Sphœranthus Indicus, L. (S. hirtus, Willd.; S. mollis, Roxb.)
Nom. Vulg.—Sambog̃-gala, Tag.
Uses.—This plant seems to possess anthelmintic properties and for this purpose it is administered in powder, 2–4 grams with a little molasses or syrup. It is bitter and aromatic and is given in diseases of the stomach and intestines for its tonic and stimulant effect. The odor of the drug is transmitted to both urine and sweat. In India it is used in “bilious diseases” and to dissipate all sorts of tumors. The Hindoos cook it with flour, lard and sugar and eat the mixture as a tonic and to prevent gray hair and baldness. They also give the seed, fried in oil, as an aphrodisiac. The aqueous distillate is a good preparation as it contains the active principle of the plant, a yellow, viscid, essential oil.
Botanical Description.—A plant about 1° high, stem and branches bearing 3 serrate wings. Leaves premorse, lanceolate, decurrent, downy. Flowers white, in a globose head, divided into 50 or more groups each with its own calyx of 9 or 10 leaflets surrounding 2 or 3 hermaphrodite, 5-toothed, campanulate flowers. Anthers 5, united. Style 1, thick at extremity. Stigma none. Corolla of pistillate flowers very minute, with 3 obscure teeth. Stigma of 2 down-curved divisions. One seed, 4-angled, imbricated.
Habitat.—The rice fields. Blooms in January.
Spilanthes Acmella, L.
Nom. Vulg.—Hagonog, Tag.; Agonoy, Sp.-Fil., Vis.(?); Palunay, Pam.
Uses.—Some native herb-doctors use the root as a purgative, giving a decoction of 4–8 grams to a cup of water. The infusion is used locally for itch and psoriasis. Internally it has a diuretic effect and is reputed to be a solvent of vesical calculi. The leaf juice and the bruised leaves are applied to wounds and atonic ulcers. These leaves with those of “sambon” and “sampaloc” (tamarind) are used to prepare aromatic baths for convalescents, rheumatics and pregnant women.
Botanical Description.—A plant with stem drooping, square, grooved, covered with drops of gum resin. Leaves opposite, cordate, oval, lanceolate, serrate, 3 prominent nerves covered with short down. Petioles short, grooved. Flowers yellow, in a sort of umbel, with 3 or more flowerets on long peduncles. Common calyx, 9–11 narrow sepals, concave, fleshy, in 2 rows. Hermaphrodite disk-flowers 40 or more. Corolla tubular, 5-toothed. Anthers longer than corolla. Pistil longer than stamens. Style bifid. Pistillate flowers, 15 or more, forming the rays. Corolla monopetalous, 3-toothed. Style and stigma as in hermaphrodite flowers. Seeds of hermaphrodite flowers quadrangular, crowned by one long awn, and the rudiment of another. Seeds of ray flowers small and sometimes flattened, 2 awns, of which one alone lengthens and becomes conspicuous. Receptacle covered with concave scales.
Habitat.—Grows along the shores of the sea and of rivers. It is very well known.
Artemisia vulgaris, L. (A. Indica, Willd.)
Nom. Vulg.—Ka-María, Santa María, Tinisas, Tag.; Indian Wormwood, Indo-Eng.
Uses.—The native women use the infusion of its aromatic leaves to induce menstruation. It is also used as an abortifacient, but is too mild a uterine stimulant to be reliable for that purpose. Its stomachic and tonic properties are common knowledge in the Philippines. The Hindoos use it for those effects and as an antispasmodic in amenorrhœa and hysteria. Dr. Wight states that the leaves and tops are useful in nervous troubles resulting from debility and that a decoction of them makes a good fomentation for phagedenic ulcers.
The infusion is prepared in the proportion of 10–30 grams of leaves to 1 liter of water and the powdered leaves are given in doses of 4–8 grams; the aqueous extract 30–40 grams a day. For amenorrhœa the drug is given daily for a week preceding the menstrual date.
Botanical Description.—A plant 3° high, stem straight, woody, square toward ends of branches. Leaves alternate, tomentose, decurrent, divided in several places, medium lanceolate. Flowers straw-colored, in axillary and terminal, 1-ranked spikes. Common calyx cylindrical, 2 circles of oval, scarious leaflets around its border, 11 hermaphrodite disk-flowers and about 5 pistillate ray-flowers. Hermaphrodite: Corolla bell-shaped, 5 obtuse teeth; stigmas 2, bent to the sides. Pistillate: Corolla diminutive, 5 toothlets; anther none; stigmas 2. Seeds of both small and quadrate, smaller in the latter. Receptacle nude.
Habitat.—Grows throughout the islands and is well known.
Carthamus tinctorius, L.
Nom. Vulg.—Azafrán de la tierra, Sp.; Biri, Kasubha, Katsumba, Lago, Tag.; Kasabba, Vis.; Kasubha, Kastumba, Pam.; Bastard Saffron, Dyer’s Safflower, Eng.
Uses.—This plant must not be confounded with Curcuma longa, L., whose tuber is also frequently called saffron (azafrán), and is used to color food.
The flower is the part employed as a condiment coloring the food yellow. Some use them internally in doses of 4 grams to cure icterus. The leaves coagulate milk. The seeds are purgative in dose of 8–16 grams, bruised and taken in emulsion, or 15–30 grams in decoction.
The following is the chemical analysis of the plant:
Yellow coloring matter, soluble 26.1–36.0
Carthamic acid 0.3– 0.6
Extractive matter 3.6– 6.5
Albumin 1.5– 8.0
Wax 0.6– 1.5
Cellulose, pectin 38.4–56.0
Silica 1.0– 8.4
Oxide of iron, aluminum, oxide of manganese 0.4– 4.6
(Salvetat.)
Botanical Description.—A plant 3° high, root gray and spindle-shaped. Stem straight, few branches. Leaves scattered, sessile, partially embracing the stem, lanceolate, serrate with hooked teeth. Flowers yellow, terminal in a sort of corymb. Common calyx semiglobose, with imbricated scales, the border often bearing thorns; numerous hermaphrodite disk flowers, with corolla very long, funnel-form, 5-toothed. Style longer than the stamens. Stigma bifid. Seed large, lacking pappus.
Habitat.—Cultivated in the gardens.
Plumbagineæ.
Leadwort Family.
Plumbago Zeylanica, L. (P. viscosa, Blanco.)
Nom. Vulg.—Sagdikit, Tag.; Bagbag, Talankaw, Iloc.; White-flowered Leadwort, Eng.
Uses.—The root is vesicant and is used by the natives for this purpose. (P. rosea, L., common in India, is more powerful. The Pharmacopœia of India states that both species are worthy of further investigation.) According to the Sanscrit authors it increases the appetite and is useful in dyspepsia, piles, dropsy, diarrhœa and skin diseases. The Filipinos use the infusion locally for itch with good results. A favorite medicine of the Hindoos for flatulence is the old recipe of Susrutas, composed of equal parts of the following substances in powder:
Botanical Description.—Plant with stem declined, angular. Leaves lanceolate, entire, rather downy. Petioles at their base embrace the stem. Flowers white, in axillary spikes. Individual involucres, 3 oval leaflets, the lower larger. Calyx long, cleft almost to the base in 5 lineal parts thickly set with small glands, exuding a sticky gum. Corolla salver-shaped, the tube long, square, throat bare, limb divided into 5 obovate parts, ending in stylets. Stamens 5, inserted near the base of the corolla, almost as long as the tube. Style a little shorter than the stamens. Stigma, 5 parts. One long seed enclosed within the calyx, pentangular, covered with a membranaceous skin.
Habitat.—In Tanauan (Batangas).
Sapotaceæ.
Sapodilla Family.
Achras Sapota, L.
Nom. Vulg.—Chico, Sp.-Fil.; Tsiku, Tag.
Uses.—The chico is one of the popular fruits of the Philippines, much appreciated by Europeans as well as the natives. When not entirely ripe it yields a resinous juice that sticks to the lips and affords a disagreeable taste; but when once thoroughly ripe it has a slightly vinous, sweetish taste and is easily digested. Therapeutically its seeds are used as a diuretic, but large doses should be avoided as they contain a small proportion of hydrocyanic acid. The proper dose is 5–6 mashed seeds in sweetened water. They contain, in addition to the above, a fatty substance of the consistency of butter.
The trunk exudes, when incised, a milky resin, closely resembling guttapercha and possibly susceptible of the same uses.
Botanical Description.—Trees, about 11° high, with leaves lanceolate, keeled, entire, glabrous. Flowers pure white, solitary or by twos, terminal, very long peduncles. Calyx, 6 sepals, 3 within the others, inferior persistent. Corolla jug-shaped, the border divided into 12 parts, the 6 smaller ones alternating and within the others. Stamens 6, inserted near the border of the inner petals and opposite the outer circle. Filaments very short. Style long. Stigma obtuse, fruit globose, resembling a small pear, russet brown, crowned with the hardened style, more than 10 compartments, each containing a seed. Seed oval, flattened, joined to a central fleshy axis.
Habitat.—Common all over the Archipelago. Blooms in April.
Mimusops Elengi, L.
Nom. Vulg.—Kabiki, Tag.
Uses.—Its flowers are fragrant and generally well known. The trunk bark is astringent, and in decoction is given by mouth for fevers and diarrhœa. Locally is used as an injection for blenorrhœa, as a gargle for sore throat or relaxed uvula, and a mouth wash to harden the gums. Horsfield states that the Javanese use it as a tonic and antiperiodic. In India an aqueous distillate is employed as a perfume and therapeutically as a stimulant. In Concan they chew the green fruit for toothache and to harden relaxed gums. The decoction of the green fruit serves the same purpose and besides is used to wash wounds and ulcers.
Botanical Description.—A large ornamental tree with leaves alternate, oblong, coriaceous, green. Flowers small, straw-colored, star-shaped, very fragrant. Calyx, 8 sepals. Corolla gamopetalous, 16 oblong, lanceolate divisions. Stamens 8, free, short, alternating with 8 petaloid, conical, pubescent staminodia. Ovary free, many ovules. Fruit fleshy, oval, smooth, yellow when ripe, with one or several locules according to the number of matured seeds. Seeds solitary, oblong, flattened.
Habitat.—Cultivated in the gardens.
Oleaceæ.
Olive Family.
Jasminum Sambac, Aiton. (Nyctanthes Sambac, Blanco.)
Nom. Vulg.—Sampaga, Tag.; Sampaguitas, Sp.-Fil.; Arabian Jasmin, Eng.
Uses.—The flower is the most popular and beloved of any in the Philippines (and is commonly referred to as the national flower). In decoction it is used as an eye-wash in catarrhal conjunctivitis. In India the flowers and the leaves have a merited reputation as a lactifuge; 2 handfuls of flowers bruised and applied without moistening, once or twice a day, sometimes checks the secretion of the milk within 24 hours, but generally 2 or 3 days are required for a complete effect.
Botanical Description.—Stems scarcely climbing, flattened, pubescent. Leaves opposite, cordate base, lanceolate-ovate, entire, glabrous. Flowers in small, close clusters, white, fragrant. Calyx-teeth 8–9, long and awl-shaped. Corolla, long tube, 7–8 rounded lobes. Stamens 2. Style 1. Stigma cleft in 2 laminæ.
Apocynaceæ.
Dogbane Family.
Allamanda cathartica, L.
Nom. Vulg.—Not known.
Uses.—As this plant has no common name in the Philippines it is most probable that the natives do not use it. The Portuguese introduced it into India from Brazil. A decoction of the leaves is purgative and is used in lead colic. The milky juice of the plant is emetic and cathartic in large doses, but simply laxative when given in doses of 8 or 10 drops. On account of its possible violent cathartic action great prudence should be exercised in prescribing it.
Botanical Description.—A twining shrub with leaves in fours, bright green, oblong, covered with rough hairs. Flowers in compound spikes, yellow. Calyx 5-toothed. Corolla 5-lobed, funnel-form. Stamens 5, inserted in throat of corolla, which above them is closed by a crown of hairs. Ovary 1-celled with 2 many-ovuled placentæ. Style cylindrical, terminating in a bilobulate cone. Capsule globular, about the size of a pea, black, coriaceous, thorny, bivalvate. Seeds numerous, each encircled by a broad membranous wing.
Habitat.—In Calauang and other parts of Luzon and Panay.
Thevetia nerifolia, Suss. (Cerbera Thevetia, L. and Blanco)
Nom. Vulg.—Campanelo, Sp.-Fil.; Exile or Yellow Oleander, Eng.
Uses.—This shrub is very common in gardens, well known by its pretty yellow, bell-shaped flowers. The trunk bark possesses antiperiodic properties first described by Descourtilz and confirmed later by Dr. G. Bidie and Dr. J. Short. Both the latter used the tincture in 10–15-drop doses 3 times a day. This tincture was prepared by macerating for one week in 150 grams of alcohol 30 grams of fresh bark finely divided. This preparation operates as an emetic and purgative in doses of 30–60 drops. It is evident that the plant possesses very active, even poisonous properties and should be employed with great caution. The decoction of the bark is given as an emetic and cathartic, but very imprudently because there is no means of determining the quantity of active principle, shown by chemical analysis to be a dangerous product.
The fruit is very bitter and acrid. The seeds yield by expression 35 to 41% oil (De Vry) and 57% when treated with benzol. It has an agreeable odor resembling that of sweet almonds, its density is 0.9148 at 25° and it is perfectly clear and transparent at that temperature. At 15° it thickens and at 13° solidifies. According to Oudemans it consists of 63% triolein and 37% tripalmin and tristearin; it is not poisonous. After expression De Vry obtained from the caked residue 4% of a crystalline glucoside called by him thevetin. Blas, of the Academy of Medicine of Belgium, studied it later and described it as a white powder of small colorless scales, odorless, very bitter, soluble at 14° in 122 parts of water, in alcohol, in crystallizable acetic acid, insoluble in ether; formula C54H34O24. Concentrated sulphuric acid dissolves it, producing a dark red color that changes to cherry red and then after several hours to violet. The color disappears if water be added. Boiled in acid solution the glucoside changes to a new substance, theveresin (C48H70O17), white, amorphous, slightly soluble in boiling water and in alcohol, insoluble in benzine or chloroform, soluble in alkalies, very bitter. Both substances are energetic narcotic poisons; but the plant contains another even more powerful poison isolated by Warden, of Calcutta; it does not form crystals, it is very bitter, freely soluble in water, and is turned yellow by sulphuric and nitric acids.
Thevetin and theveresin exercise a marked toxic effect on the heart. The former induces emetic and cathartic phenomena, trembling and progressive weakness. The latter does not cause vomiting or diarrhœa, but anæsthesia and rigidity of the limbs. Both poisons arrest the heart in systole. Injected hypodermically they are irritant, are eliminated by the liver, but are not found in the urine.
Botanical Description.—A shrub, about 10° high, with leaves nearly sessile, somewhat bunched at the ends of the branches and overlapping, lanceolate, entire, glabrous. Flowers about 2′ long. Calyx 5-toothed. Corolla straw-colored, cylindrical, very narrow below, but the limb very large, spreading into 5 lobes with greenish, superimposed borders. Stamens 5, inserted in the throat, anthers lanceolate. Ovaries 2, united at base, free above, unilocular. Style simple, enlarging at the base in a bilobed stigma. Fruit a fleshy drupe resembling somewhat a small apple, the pit very hard, semilunar, flattened, with 4 compartments and as many solitary seeds.
Habitat.—Common in all gardens and on the seashore.
Cerbera Odallam, Gaertn. (C. manghas, Bl. & Blanco.)
Nom. Vulg.—Toktok-kaló, Tag.
Uses.—The milky juice of the plant is emetic and purgative. The chemist De Vry has isolated from it a poisonous alkaloid analogous to “thevetin,” which has just been considered. The seeds are likewise emetic and toxic. The Javanese call the fruit “bimaro” and affirm that it possesses the same properties as “datura.” The bruised leaves are used locally for hepatic eruptions; the bark is used for the same purpose and is purgative.
The use of the plant is dangerous and is condemned by the Pharmacopœia of India.
Botanical Description.—A small shrub with forked branches. Leaves (overlapping) at ends of branches, lanceolate, entire, glabrous. Flowers in umbellate spikes. Calyx, 5 caducous lobules. Corolla white, twisted, cylindrical, with salver-shaped limb divided in 5 rhomboid lobes, throat stellate and woolly. Stamens 5. Filaments joined to the corolla, their ends thickened. Anthers arrow-shaped. Ovary, 2 uniovulate locules. Style, same length as stamens. Stigma thick, conical, lobulate. Two drupes joined at the base (one usually aborted), brown, large, oval, fleshy, with woody fibrous nut of a single flattened seed.
Habitat.—Luzon. Blooms in July.
Plumeria acutifolia, Poir. (P. alba, Blanco.)
Nom. Vulg.—Calachuche, Sp.-Fil.; Kalatsutsi, Kalasusi, Tag.
Uses.—This tree, beloved for its fragrant flowers, has a wide therapeutic use in India and the Philippines. The bark is a bitter hydragogue cathartic and is given in decoction (5–10 grams to 200 water) principally for dropsy; however the milky juice of the trunk is preferable for this purpose, given in emulsion in doses of 0.50–0.80 grams. The bark and the tips of the branches are given as an emmenagogue.
The bark of the root and of the trunk is an excellent remedy for blenorrhagia. The fresh bark is thoroughly comminuted and mixed with sweetened water in the proportion of 60 grams to 4 liters; this mixture is put in the sun for 4 days, and shaken from time to time. It is then strained and given in doses of 4–5 glassfuls a day, at the same time with refreshing and emollient drinks, and prolonged tepid baths. At first this preparation exerts a purgative action, but later acts upon the urinary organs, rapidly lessening the suppurative process in urethritis. The bark may also be associated with wine or beer, in the proportion of 30 grains to the liter, the dose being 2–4 small cupfuls a day and Dr. Grosourdy employs the extract of the bark in doses aggregating 0.20–0.25 gram a day, gradually increased till at the end of a week 6 grams are taken daily (Dr. J. Amadeo).
The bruised leaves are applied locally to contusions to reduce the swelling. The juice is used externally as a rubefacient in rheumatic affections of the joints. In Concan they use a decoction of the root for diarrhœa. The flower buds are chewed with buyo, for intermittent fever and the juice is applied locally for itch.
Peckolt and Geuther isolated from the bark the glucoside, agoniadin (C10H14O6), which crystallizes in silky crystals fusible at 155°, slightly soluble in water, alcohol, bisulphuret of carbon, ether and benzine; soluble in nitric or sulphuric acids. In solution it is a golden yellow soon changing to green. Boiled in a dilute acid it splits into glucose and an undetermined substance. Oudeman obtained plumieric acid (C10H10O5) from the milky juice deprived of its resin; the acid exists as microscopic, needle-like crystals, soluble in boiling water, alcohol and ether. It melts and decomposes at 130°.
Botanical Description.—A tree, 12–18° high, commonly cultivated for ornament, well known in the islands, almost constantly bearing fragrant flowers, but rarely bearing fruit. Branches forked and peculiarly stumpy at the ends. Leaves alternate, broad lanceolate, entire, glabrous, the apices curved downward. Petioles short. Flowers creamy white, light yellow in the throat. Calyx 5-toothed. Corolla twisted, funnel-form, 5-lobed. Stamens 5, hidden in depths of the tube. Anthers dart- or arrow-formed. Style very short, thickened above. Stigma 2-parted. Two horizontal, cylindrical and long follicles joined at their bases, with numerous seeds in hollow receptacles, each seed encircled by a wing.
Alstonia scholaris, Br. (Echites scholaris, L. and Blanco.)
Nom. Vulg.—Dita, Tag.; Dallopawen, Iloc.; Dita or Alstonia Tree, Eng.
Uses.—The trunk bark is a febrifuge of great importance; it is official in the Pharmacopœia of India and is widely used in the Philippines. Personally I have had occasion to use it in several cases of malarial fever in the town of San Mateo near Manila. It is astringent, anthelmintic and antiperiodic, highly useful in chronic diarrhœa and dysentery, not only for its astringent effects but for its tonic and restorative action. As a tonic it gives as good results as quinine. The dry powdered bark is given internally in wafers of 20–30 centigrams. The infusion is prepared from 15 grams of the dry comminuted bark to 300 of water. The dose is 30–60 grams 2 or 3 times a day.
Another convenient preparation is the tincture, 75 grams of the powdered bark macerated 7 days in 500 grams of alcohol, shaking from time to time. It is then filtered and enough alcohol added to make up the 500 cc. The dose is 4–8 grams a day.
I have often used the following wine as a tonic for convalescents and patients suffering from general debility: Finely powdered bark, 25 grams, muscatel or dry sherry one bottle; macerate a week, shaking every day, and filter; dose ½ wineglass with equal parts water a few minutes before each meal; children or very weak patients should take it after eating; it should always be diluted.
G. Grupe, a Manila pharmacist, treating the bark in 1883 by the same process as that used in the preparation of quinine, obtained a bitter substance which he named Ditaine. According to Grupe Dr. Pina used this substance with great success in the treatment of malarial fevers, but neither Grupe’s report nor Pina’s experiment are of any scientific value, inasmuch as they have neglected to mention the doses in which the so-called alkaloid was employed. Later analyses by Hesse and Jobst revealed several principles: two alkaloids ditamine (C16H19NO2), soluble in ether; Ditaine or Echitamine (C22H28NO4 + H2O) insoluble in ether, soluble in water; acetic acid and two amorphous substances dextrogyrous in ethereal solution, one of them a resin, Echicauchina (C25H40O2), the other neutral, Echiretin (C35H56O2); two crystallizable principles, dextrogyrous: Echicerin (C30H48O2), Echitein (C42H70O2) and Echitin (C32H52O2).
Ditaine is employed under the same circumstances and in the same dose as quinine. (The Hindoo writer, K. L. Dey, states that the plant yields an inferior quality of gutta-percha.)
Botanical Description.—A tree, 50 or more feet high, the trunk covered with small eminences resembling the scars of thorns. Branches radiating. Leaves radiating, 5, 6 or more, somewhat elliptical in form, pointed at the apex. Petioles very short, with a pointed glandule on the inner surface of the base. Flowers white, terminal, in umbellate racemes. Calyx very short, 5-toothed. Corolla twisted, tubular, the limb 5-lobuled; throat open, encircled with down. Stamens 5, hidden within the throat and inserted on the tube. Filaments almost wanting. Anthers arrow-shaped. Style as long as the stamens, somewhat flattened, a scarcely visible line throughout its length. Stigma bifid, placed above a cylindrical zone, two follicles, 1° long and 1″ thick, twisted like a string, containing the seeds in a row. Seeds cylindrical with a hairy awn at both ends.
Habitat.—In the forests of Luzon, especially in Batangas. Blooms in April.
Nerium odorum, Aiton. (N. oleander, L. and Blanco.)
Nom. Vulg.—Adelfa, Sp.; Baladri, Tag.; Sweet-scented Oleander, Eng.
Uses.—In the Philippines and in Spain this plant is well known to be poisonous. The bark and the leaves of both the red-flowered and white-flowered varieties are boiled in cocoanut oil and the product is used for inunction in itch and other skin diseases. The bruised root is a useful application for chancroids.
We have stated that the plant is poisonous, and indeed it is actively so in the tropics. It is now recognized as an energetic cardiac poison, comparable with strophanthus, destined to play an important part in therapeutics. Dr. Pouloux has made a study of the hydro-alcoholic extract of oleander and reports that it exerts a marked effect on the heart of frogs and rabbits, arresting them in systole. Where there is asystolia, such as we encounter in Bright’s disease, without compensation, it stimulates the heart and increases the urine in the same manner as digitalis. No contraindications to its use are as yet known. It occasions no disagreeable symptoms and may be used many days consecutively provided that the daily dose does not exceed 10–15 centigrams.
The poisonous properties of the plant reside in two alkaloids isolated by Lukowsky from the leaves: oleandrine, extremely toxic and pseudo-curarine, as its name indicates, resembling curare in its action. Oleandrin is yellow, semicrystalline, soluble in water, alcohol, ether, chloroform and olive oil; fusible at 70–75° and changing to a greenish oil. With HCl it forms a crystalline salt. It is a violent irritant of the mucous membranes and given internally it causes emesis, diarrhœa, tetanic convulsions and death. It arrests the cardiac movements in doses of 25 milligrams.
Loiseleur-Deslongchamps experimented with the drug on his own person, using a solution of 30 grams of the extract in 120 grams of wine. He began by taking three drops of this preparation four times a day, adding a drop to each dose every day, so that at the end of 12 days he was taking 48 drops between 6 a. m. and 9 p. m. He reached a maximum of 64 drops a day but was forced to abandon his experiment at that point on account of the unpleasant symptoms induced—loss of appetite, great weakness and muscular pains. His deduction was that the plant contained a “destructive and irritant principle.” The experiment is of interest as demonstrating the maximum dose of the drug.
The active principles of the plant reside principally in the leaves and bark, but that they are abundantly present in other parts is proved by the death of several soldiers in Corsica from having eaten meat roasted on a spit of oleander wood.
Botanical Description.—A small tree, about 6° high. Leaves coriaceous, lanceolate, entire, glabrous. Flowers in terminal cymes, rose-color or white, single or double. Calyx 5-parted. Corolla 15 petals, the inner ones larger, disposed in 3 groups of 5. Stamens 10, fixed on receptacle; filaments short. Style shorter than stamens. Two follicles, sharp-pointed, channeled, containing many imbricated seeds each with an awn.
Asclepiadaceæ.
Milkweed Family.
Calotrops gigantea, R. Br. (Asclepias gigantea, Willd. and Blanco.)
Nom. Vulg.—Kapal-kapal, Tag.; Swallow-Wort, Eng.; Mudar, Indo-Eng.
Uses.—This plant is official in the Pharmacopœia of India as an alterative, tonic, diaphoretic and emetic. J. J. Durant, having observed that the natives used it for dysentery, experimented with it quite successfully in that disease. For adults he gradually raised the dose from 1.10 to 4 grams, preferring smaller doses, however, for mild cases. To children he prescribed 5–10 centigrams for each year of age, 3 or 4 times a day. He remarked that the effects produced were identical with those of ipecac administered in Brazilian fashion.
The part of the plant used is the dry root powdered. The usual dose is 15–50 centigrams 3 times a day, gradually increased; as an emetic 2–4 grams.
The milky juice that escapes from the stem on the slightest abrasion is a drastic purgative, given commonly in dropsy, lumbricoids, etc. Pledgets of cotton impregnated with the juice and packed in the cavities of carious teeth, relieve toothache. It is applied locally for various skin diseases, including syphilitic ulcers, and as a depilatory.
Some races of India, such as the Rajputs of the districts of Allahab and of Khangor, use this milk-juice to poison their female infants whom they are accustomed to regard as a vexatious burden. Therapeutically they use it with honey, locally for sore throat.
The dry and powdered juice has been used in small doses as an alterative in the treatment of tuberculous leprosy, but it has not given results any better than many other drugs. In syphilis and mercurial cachexia its results are less doubtful.
In 1881 Dr. Riddell obtained a sort of gutta-percha from the juice, previously observed by Professor Redwood.
Mooden Sheriff states that the most active parts of the plant are the root bark and the dried juice. He adds that the action of the juice is irregular and even dangerous, and that the bark is active in direct proportion to its age. He recommends that the inert tuberous layer of the bark be removed; prepared thus and powdered it is emetic in doses of 2.50–3 grams.
Duncan claims to have isolated from the bark an active principle which he called mudarin from “mudar,” the Indian name of the plant. Following the same process Flückiger was unable to obtain the substance, but did isolate 1½% of an acrid resin, soluble in ether and in alcohol; a mucilage and a bitter principle decolorized by chloroform and ether. It is probable that this is the active principle of the “Calotropis gigantea.”
Warden and Waddell in 1881 isolated a substance crystallizable in nodular masses, with the formula C17H28O, analogous to the albana of gutta-percha.
Botanical Description.—A small tree, 7–8° high, with straight stem, branched and woody. Leaves sessile, opposite, cleft at the base, oval, fleshy and woolly. Flowers lateral in simple umbels of 3 or more flowerets. Calyx 5-cleft. Corolla monopetalous, 5 acute lobes, white, of rare and beautiful form. Nectaries 5, united throughout their length with the receptacle, their bases curved like the sides of the fleur de lis.
Above the nectaries is a 5-angled crown, the extremity of the receptacle; in each angle a black anther. Two large follicles narrowed at the ends, woolly, the apex somewhat curved to one side, containing many imbricated seeds, each with a tuft of long hairs.
Habitat.—Bauang, Taal and the volcanic island of Taal. Blossoms in April.
Tylophora asthmatica, Wight. (Asclepias asthmatica, Roxb.)
Nom. Vulg.—(?)
Uses.—We are ignorant of the uses the Filipinos make of this plant. It is official in the Pharmacopœia of India, the dry powdered leaf being the part employed, and its emetic, diaphoretic and expectorant properties are well known in that country. Roxburgh has used the root as an emetic and Anderson has employed it in the same manner as ipecac in dysentery. Later the experience of Anderson was confirmed by O’Shaughnessy; though in place of the root he used the leaf, the properties of which he regards as more certain and uniform.
Dr. J. Kirkpatrick has noted that the juice of the root and its powder are used by the natives of Mysore as an emetic, and adds that he himself has used it for that purpose in a thousand cases with good results. In its effect on dysentery as well as in its emetic effect it resembles ipecacuanha. He used the powder in doses of 1.20–1.80 gr., to which he added 3–6 centigrams of tartar emetic when he desired to obtain an energetic emetic action. Like O’Shaughnessy he prefers the powdered leaves. He considers it a good substitute for ipecac, not only as an emetic, but as a remedy in asthma, dysentery and catarrhal affections; Drs. Oswald and Mooden Sheriff have made the same observations. The latter advises the administration of the juice of the plant for snake bites till vomiting is produced; then follow with diffusible stimulants.
The emetic dose of the powdered leaves is 1.20–1.80 grams, the expectorant and diaphoretic dose 10–30 centigrams. The concentrated infusion of the leaves has an acrid taste. Tannic acid, the neutral acetate of lead and caustic potash produce with it an abundant precipitate; the perchloride of iron colors it a dark green. Broughton, of Ootaemund (India), informed Hanbury and Flückiger, from whom we quote, that in 1872 he obtained a very small quantity of crystals from a large quantity of leaves. He had not enough to make an analysis, but injected a solution of the crystals into a dog with resulting vomiting and diarrhœa.
Botanical Description.—A vigorous plant with scandent stem 2–4 meters long, the more recent growth woolly. Leaves opposite, entire, 5–12 centimeters long and 2–6 broad, oval or rounded. Petiole striated and short. Flowers in umbelliferous cymes, compound, axillary, solitary and alternate, with woolly peduncles; hermaphrodite, regular, small, of a pale green color inside and a light purple outside. Calyx gamosepalous, with 5 lobules. Corolla gamopetalous, 5 oval, twisted lobules. Staminal crown composed of 5 fleshy scales, joined to the staminal tube. Stamens 5, inserted on the throat of the corolla, filaments joined to form a very short tube with anthers straight, short and crowned by a membranous bilocular appendix. The gynœcium consists of 2 unilocular ovaries each containing an indefinite number of ovules. Style with a pentagonal stigma which bears in each angle a glandular body. Fruits compound with two separate follicles, large, lanceolate, smooth, 8–10 centimeters long and 5 in circumference. Each encloses a seed, hairy, albuminous with straight embryo and flattened cotyledons.
Habitat.—Mountains of San Mateo.
Loganiaceæ.
Logania Family.
Strychnos Ignatii, Berg. (S. Philippensis, Blanco; Ignatia amara, L.; Ignatia Philippinea, Lour.)
Nom. Vulg.—Pepita Fruta, Sp.-Fil.; Pepita sa katbalog̃an, Kabalog̃an, Tag., Pam.; Pangaguason, Aguason, Kanlara, Mananaog, Dankagi, Katalog̃a, Igasud, Vis.; St. Ignatius Bean, Eng.
Uses.—The part of the plant employed is the seed, known in addition to the above common names as Pepita de San Ignacio and Pepita de Cabalonga (for katbolog̃an). The natives handle it with the greatest imprudence, selling everywhere in the markets and in the Chinese shops, called tindag̃-bayag̃. It is not only a remedy among them, but a sort of panacea, to which they attribute, among other virtues, that of expelling evil spirits, simply worn about the neck. They grate it with a piece of earthen pot, mix with a little “tuba” vinegar and apply it to the temples for headache. In bites of poisonous animals they advise the application of the powdered seed over the wound, a treatment which instead of being beneficent might easily be harmful to the patient. Before proceeding further, let us give the chemical composition of the seeds in order that their uses may be the better understood.
Strychnine is found in them in the proportion of ½–1½ and brucine ½%–1.4%. Flückiger and Hanbury by drying it over sulphuric acid and burning it with “cal sòdica” obtained 1.78% of nitrogen which represents 10% of albuminoid material. Strychnine and brucine exist in combination with igasuric acid discovered by Ludwig in 1873. The proportion of both the alkaloids is greater than in the seeds of nux vomica which contain only .25–.50% strychnine and .12–.05% brucin, although some authors give it as high as 1.01%. Strychnine can be obtained more readily and in larger proportions from St. Ignatius bean, but it is generally obtained from nux vomica seeds on account of the cheapness of the latter.
It is more energetic than nux vomica and its use in medicine should be condemned, preference, however, being given to the official preparations among which the best known is that commonly called “Bitter Drops of Beaumé,” of which the following is the composition:
Grated St. Ignatius’ beans 500 grams.
Potassium carbonate 5 grams.
Soot (?) 1 gram.
60% alcohol 1,000 grams.
Macerate for 10 days, strain, express and filter. Dose, 1–16 drops in a little water or wine before each meal, for dyspepsia, anæmia, convalescence from fevers, and other conditions in which a tonic is indicated. The indications for the use of this drug are the same as those for nux vomica, keeping in mind the difference in dose.
Botanical Description.—This plant grows in the deep forests of Samar and Masbate. That industrious and distinguished botanist, D. Regino García, found it growing abundantly in Paranas, Island of Samar. It is a robust vine, the trunk sometimes as thick as a man’s thigh, climbing to the tops of the highest trees, apparently without preference as to its host, inasmuch as he saw it growing indifferently on Ficus, Dipterocarpus, Litsaca, etc. The seed which most interests us and is very common, is about the size of an olive, round and convex on one side, angulose and flattened on the other by being compressed with many others within the fruit which contains 50 of them. Its surface is blackish with a gray-blue tinge. It is hard and corneous. Its taste is extremely bitter.
Branches opposite, smooth, the ends square. Leaves opposite, oval, much pointed at the apex, entire, glabrous, with 3 prominent nerves. Petioles very short. Flowers in panicles of many flowerets. Calyx inferior, 5-cleft, very short. Corolla 6–7 times longer than the calyx, funnel-form, 5-lobed. Anthers 5, sessile, fixed in the throat of the corolla. Ovary very small. Style filiform, same length as the stamens. Stigma truncate and thick. Drupe globose, often oval, large, smooth, with thick, woody shell of a single compartment containing seeds as described above.
Boraginaceæ.
Borage Family.
Ehretia buxifolia, Roxb. (Carmonea heterophylla, Blanco.)
Nom. Vulg.—Mag̃it, Alag̃itg̃it, Tag., Vis.
Uses.—The leaves dried in the shade are used in some Visayan towns, in infusion to take the place of tea. The root is used by the Hindoo physicians as an alterative. Dr. R. Ross has employed it for that purpose in a decoction of 60 grams to 500 cc. of water; 60 cc. a day of this preparation gave him good results in secondary and constitutional syphilis. The Mohammedans of India consider the root an antidote for vegetable poisons.
Botanical Description.—Small tree, 5–6° high, trunk straight. Leaves alternate or bunched in 3′s or 4′s at the nodes, lanceolate or spatulate, 3-toothed at apex, sometimes serrate toward the apex, set with short, stiff hairs. Petioles very short. Flowers axillary, in racemose panicles of a few flowers each. Common peduncle long, pedicel short. Calyx free, bell-shaped, persistent, divided almost to base into 5 narrow, downy parts. Corolla bell-shaped, 5 oval lobules. Stamens 5. Ovary oval, within the flower. Style bifid. Stigmas simple, truncate. Drupe globose, with hard, slightly furrowed putamen of 6 locules and solitary seeds.
Habitat.—Malinta and many other parts of the Visayas. Blooms in January.
Convolvulaceæ.
Convolvulus Family.
Ipomœa hederacea, Jacq. (I. nil, Roth.; Convolvulus nil, L. and Blanco.)
Nom. Vulg.—Bulakan, Tag.; Kala-Danah, Indo-Eng.
Uses.—This plant is not used as a medicine by the Filipinos, but is official in the Pharmacopœia of India from which we copy its indications and official preparations.
The seed is the part employed, its cathartic properties being much like those of jalap, though less energetic. An excellent substitute for the latter is 2 or 3 grams of kala-danah seeds in powder form, and no unpleasant effects attend its operation.
The official preparations are:
Extract of Kaladana.—Dose, 30–60 centigrams in pill.
Powdered seeds 500 grams.
Alcohol 2 liters.
Water 4½ liters.
Tincture of Kaladana.—Dose, 8–12 grams.
Seeds 75 grams.
Alcohol 500 grams.
Compound Powder of Kaladana.—Dose, 3–3½ grams.
Powdered seeds 150 grams.
Acid tartrate of potassium 270 grams.
Powdered ginger 30 grams.
The last is an excellent substitute for the corresponding preparation of jalap.
Resin of Kaladana.—Dose, 30–50 centigrams. It is prepared like resin of jalap and is a safe and sure purgative. In mass it has a dark color, but is gray when powdered. The odor is rather unpleasant, the taste sweetish and then acrid, nauseous, persistent, exciting the saliva and irritating the fauces. It was introduced into practice by Dr. G. Vidie.
Botanical Description.—A twiner with round, downy stem. Leaves heart-shaped, 3-lobed, the middle one broad-lanceolate, the lateral ones rather rectangular with petioles of equal length with the leaves. Flowers large, rose color or pale blue, in axillary cymes of 2 or 3 flowers each. Calyx, 5 long, downy parts. Corolla bell-shaped, 5 faint lobes. Stamens 5, free, inserted in the corolla. Ovary free, 3 biovulate locules. Style simple. Stigma trilobed. Seed vessels globose with 3 locules each containing 2 seeds. Seeds convex on dorsum, 1/2 cm. broad by 1 cm. long, testa black.
Habitat.—Manila. Blooms in August.
Ipomœa pes-capræ, Roth. (Convolvulus pes-capræ L. and Blanco.)
Nom. Vulg.—Katagkatag, Lagayray, Lampayog, Bagasoa, Kamigag, Daripay, Tagaray, Arodayday, Lambayog, Tag., Vis.; Lambayog, Iloc.
Uses.—The dry, powdered leaves are dusted over bruises and ulcers. The entire plant is very mucilaginous and the bruised fresh leaves are applied like poultices to cancers and ulcerating tumors. In India the boiled leaves are applied locally in colic and in rheumatism; the juice is given internally in dropsy as a diuretic, the pounded leaves at the same time serving as a poultice to the œdematous parts.
Botanical Description.—A plant that creeps extensively, the stem taking root. Leaves with 2 well-marked lobules. Flowers rose-lilac color, in axillary panicles with long pedicels. Corolla very large, bell-shaped, the limb 5-angled and 5-nerved. Stamens 5, unequal in height. Stigma globose, marked by a line; later it divides in two. Seed vessel ovate, 2-celled, in each cell 2 downy seeds convex on one side, angular on the other.
Habitat.—Very common on the seashore. Blooms in January.
Ipomœa Turpethum, R. Br. (Convolvulus Turpethum, L.; C. maximus, Blanco.)
Nom. Vulg.—Albohol, Sp.; Turpeth Root, Indian Jalap, Eng.
Uses.—The root, known in the Philippines as “turbita,” is a purgative and is a component part of the tincture of jalap, one of the most positive and active of known cathartics. But turpeth root is seldom used alone, for its action is so uncertain that Sir W. O’Shaughnessy pronounced the plant unworthy of a place in the Pharmacopœia of India. The dose of the powder is 1–4 grams, the resin 40–50 cgms., the decoction of the root 4–12 grams. The active principle is a resin soluble in ether and a glucoside, turpethin, C34H56O16.
In the east of India they make offerings of the flowers to the god Shiva, and also put them to more practical use by applying them to the head for neuralgic headache.
Botanical Description.—A vine with quadrangular stem. Leaves heart-shaped. Flowers axillary, numerous, in umbels. Calyx deeply cleft in 5 imbricated, ovate, fleshy parts. Corolla bell-shaped, folded. Stamens 5, unequal in height. Ovary inserted on an hypogynous disk, with 2 biovulate compartments. Style same length as stamens. Stigma bilobulate, globose. Seed vessel square, encircled by calyx, 2 locules each with 2 seeds.
Habitat.—Common in Bauang and Pasig. Blooms in November.
Solanaceæ.
Nightshade Family.
Solanum nigrum, L.
Nom. Vulg.—Hierba mora, Sp.; Konty, Onty, Gamagamatisan, Tag.; Lagpakon, Bolagtob, Lubilubi, Vis.; Kuty, Lubilubi, Bic.; Black or Common Nightshade, Eng.
Uses.—In the Philippines the entire plant is boiled and used for food, with the precaution of pouring off the first 2 or 3 waters in which it is cooked, which contain an active principle capable of causing such disagreeable symptoms as vertigo and nausea. A decoction of the leaves serves to cleanse chronic sores and in fact improves their condition; it is also used as a lotion for various forms of dermatitis, for erysipelas and old burns.
The plant is narcotic, antispasmodic and like belladonna it dilates the pupil.
In India the decoction is given internally, 200–250 grams, for hypertrophy of the liver, and it is considered a good diuretic and alterative. For such uses they heat the above dose in a clay vessel till the color changes from green to brown, when it is cooled and given next day. Its action is diuretic and hydragogue-cathartic. Mooden Sheriff recommends this treatment highly, and for dropsy further advises the aqueous extract, 12 grams during the day divided into 3 or 4 doses. Small doses of 30–60 grams of the decoction prepared as above described, are of use in some chronic skin diseases such as psoriasis.
In 1821 Defosses, of Besançon, obtained solanine from the fruit, previously isolated from the S. Dulcamara.
Botanical Description.—A plant about 2° high, stem straight, 3–4-angled, with white dots. Leaves lanceolate. Flowers white, in 2-ranked racemes. Calyx inferior, 5 persistent teeth. Corolla, 5 petals somewhat down-curved. Berry small, black when ripe.
Habitat.—Universally common. Blooms in January.
Capsicum fastigiatum, Bl. (C. minimum, Roxb.)
Nom. Vulg.—Chili picante, Sp.-Fil.; Sili, Tag.; Capsicum, Red Pepper, etc., Eng.
Uses.—The fruit of this species of pepper plant is called agí in Cuba and Porto Rico; it is in common use as a condiment in the Philippines. As a tonic and stimulant it is a useful article of food in hot countries where the digestive functions become sluggish. Used in moderation it prevents dyspepsia and consequent diarrhœa. It is used as a gargle for hoarseness, decreasing the congestion of the larynx and vocal cords.
Gargle.—
Tincture of capsicum 8 grams.
Water 160 grams.
Mix.
Recently capsicum in powder, extract, or tincture, has been recommended internally in the treatment of incipient hemorrhoids. The dose is .50 to 3 grams of the powder in pills or capsules; watery extract, 0.30–0.60; tincture, 10–30 drops.
The C. annuum, L., and other varieties of red pepper serve the same uses as the above.
Botanical Description.—Stem 4-angled. Leaves opposite, ovate-lanceolate, entire. Petioles short. Flowers greenish-white in little clusters, drooping. Corolla wheel-shaped. Fruit straight, conical, slender, scarcely 1′ long.
Habitat.—Universally common in the islands. Blooms at all times.
Datura alba, Nees. (D. Metel, Roxb. and Blanco.)
Nom. Vulg.—Talamponay, Tag., Pam.; Takbibug̃, Vis.; Dhatura, Indo-Eng.
Uses.—The applications of this species are identical with those of D. Stramonium and it is official in the Pharmacopœia of India. It is antispasmodic, narcotic and toxic, and is used quite commonly with criminal intent in India and Indo-China. The cooked and bruised leaves make an efficient poultice in articular rheumatism.
The symptoms of poisoning by “dhatura” are: dilatation of the pupil, general malaise, dryness of the fauces and skin, hallucinations, rapid pulse, coma and death or permanent mania.
The dry leaf is smoked to abort asthma, and though its action is uncertain, it is one of the many remedies that should be tried, which though ineffective in one case may in another afford positive relief in this distressing disease. Not more than 1.50 grams should be smoked in one day and their use should be discontinued if any symptom of intoxication supervenes. The Pharmacopœia of India contains a tincture made from 75 grams of the ground seeds and 500 grams of alcohol. Dr. Waring states that 20 drops of this tincture are equivalent to 6 centigrams of opium and that in some cases it has given him better narcotic results than the opium. The extract is made from 500 grams of the powdered seeds, 500 cc. ether, 500 cc. alcohol and 500 cc. water. Dose, 5–20 centigrams a day in 4 doses.
The D. fastuosa, L., known in Manila by the common name of Talamponay na itim, Tag., possesses the same properties as the above. The Filipino physician, Sr. Zamora, successfully employed a poultice of bruised leaves cooked in vinegar and applied to the forehead and backs of the hands to reduce the fever of tuberculous patients.
Neither the leaves nor seeds of these two varieties of Datura have been studied from a chemical standpoint, but there is little doubt that the active principle is the daturine (atropine and hyoscyamine) that exists so abundantly in D. Stramonium.
Botanical Description.—Plant 5–6° high, with nodose branches, forked. Leaves ovate, angled, somewhat downy. Flowers large, white, axillary, solitary. Calyx tubular, 5-toothed. Corolla funnel-shaped, the limb 5-angled and 5-folded. Stamens 5, same length as calyx. Anthers long, flattened. Stigma thick, oblong, divisible in 2 leaves. Seed vessel globose, thorny, 4-valved over the base of the calyx. Seeds numerous, flattened, kidney-shaped. (Resembles closely the common Jamestown Weed of America, though much taller with much larger flowers.)
Habitat.—Common on the shores of the sea. The D. fastuosa is differentiated by its violet flowers and double corolla.
Nicotiana Tabacum, L.
Nom. Vulg.—Tabaco, Sp.; Tobacco, Eng.
Uses.—Tobacco is a powerful sedative and antispasmodic, but owing to the accidents it may give rise to, its use in therapeutics is very limited. Like all the active Solanaceæ it is effective against neuralgia and spasm of the muscular tissues and is therefore indicated in strangulated hernia and in intestinal obstruction. In these conditions the infusion of 1–5 grams of the dried leaf to 250 grams of water is given by enema. Trousseau advises non-smokers who suffer from chronic constipation to smoke a cigarette fasting, a practice which, according to him, stimulates defecation. For the same condition the people of southern India are accustomed to apply a poultice of the bruised leaves to the anal region.
Tobacco has been used by enema to combat tetanus; Dr. Lesth, of the General Hospital for Europeans, Bombay, claims to have obtained excellent results by applying a poultice over the entire length of the spinal column. Dr. Dymock has confirmed this practice.
A decoction of the leaves is used as a lotion to destroy “pediculi capitis and pubis,” and to wash gangrenous ulcers.
The daily increasing practice of smoking, like all other subjects, divides mankind into two camps, one for and one against the habit. Both parties exaggerate their arguments. The abuse of the plant without doubt sets up disturbances of the digestion, the heart and the nervous system. It is furthermore positive that persons of a certain disposition and with certain ailments are injured by even a moderate use of tobacco. The above facts serve as arms for the opponents of the habit; the robust who smoke and drink to excess and meet with an accidental death on a railroad or from an acute disease that overtakes them in the midst of perfect health, serve as arguments for the defenders, to prove the innocence of the custom. The antiseptic qualities of the smoke and of the entire plant also lend the smoker a defensive argument, as he may uphold the habit as hygienic and highly useful in preventing microbic infection. The antiseptic power of tobacco smoke is undoubted, but it is intolerable that a physician under the pretext of avoiding self infection should enter the house of his patient and continue smoking at the bedside.
Chronic nicotine poisoning is the result of a gradual intoxication by the absorption of the active principle of tobacco, the alkaloid nicotine. Excessive smoking conduces to nicotism, more common in Europe than in the tropics, because the natives of Europe smoke the pipe and being confined in closed dwellings, breathe continuously an atmosphere of smoke; in the Philippines, on the contrary, the pipe is almost unknown and owing to the nature of the dwellings the smoking is carried on practically in the open air. An injurious practice of the Filipino smokers is that of “swallowing the smoke,” and this is a fitting point to call attention to an error of Dujardin-Beaumetz, who states that “in those who habitually swallow the smoke the nicotine acts directly upon the stomach.” The expression “swallow smoke” (tragar el humo) does not mean to force it into the stomach by an act of deglutition, and I am sure no one attempts to dispose of it in that way; but to inspire or breath it into the air passages. It is evident that this latter habit does not involve the stomach, but those who practice it expose themselves more to nicotism than those who keep the smoke in the mouth or expel it through the nose.
The first cigar causes symptoms familiar to nearly everybody; dizziness, malaise, cold sweat, vomiting, diarrhœa, dilatation of the pupils and rapid heart action—an acute intoxication. Chronic intoxication or nicotism manifests itself by disturbances of digestion, vision and especially circulation. It has been assigned as one of the causes of early atheroma and of angina pectoris. It should therefore be proscribed in persons who present symptoms of gastro-intestinal or of heart disease, and in every patient who complains of slight precordial pains, commonly attributed to flatus, but in reality cardiac neuralgia, a fugitive symptom announcing the possibility of that grave accident, angina pectoris, capable of ending the life of the patient with one stroke.
Nicotine (C10H14N2) is an oleaginous liquid heavier than water, colorless, changing to dark yellow on contact with the air. Nicotianin or “camphor of tobacco” is another substance found in the leaves, crystalline, tasteless, with an odor resembling tobacco. Nicotinic acid is a product of the combustion of nicotine.
Botanical Description.—The tobacco plant is so familiar to all Americans that its description here would be superfluous. It grows in all parts of the islands, the best qualities being cultivated in the northern provinces of Luzon, especially Cagayan and La Isabela.
Scrophulariaceæ.
Figwort Family.
Limnophila menthastrum, Benth. (Tala odorata, Blanco.)
Nom. Vulg.—Tala, Taramhampam, Tag.; Talatala, Pam.; Taratara, Iloc.
Uses.—An infusion of the leaves is given as a diuretic and digestive tonic. The plant is aromatic. It is seldom used, but is given for the same troubles and in the same doses as chamomile and Eupatorium Ayapana.
Botanical Description.—A plant 1° high, with leaves opposite, lanceolate, ovate, serrate, hairy, many small pits on the lower face. Flowers rose color, solitary, sessile. Calyx, 5 sharp teeth. Corolla tubular, curved, compressed, downy within, limb cleft in 4 unequal lobes. Stamens didynamous. Ovary conical. Style shorter than the stamens. Stigma 3-lobuled. Seed vessel, 2 multiovulate chambers.
Habitat.—Known universally. Blooms in June.
Bignoniaceæ.
Bignonia Family.
Oroxylum Indicum, Vent. (Bignonia Indica, L.; B. quadripinnata, Blanco; Colosanthes Indica, Bl.)
Nom. Vulg.—Pinkapinkahan, Pinkapinka, Taghilaw, Abag̃abag̃, Tag.; Abag̃abag̃, Vis.
Uses.—The Hindoos consider the trunk bark an astringent and tonic and use it commonly in diarrhœa and dysentery. In Bombay it has a wide use in veterinary practice as an application for the sore backs of the domestic cattle. Sarangadhara recommends for diarrhœa and dysentery the infusion of the roasted bark mixed with infusion of Bombax malabaricum.
Dr. Evers experimented with the powder and an infusion of the bark obtaining a strong diaphoretic action. He obtained the same effect with baths containing the bark and reported successful results in thus treating 24 cases of rheumatism. The dose of the powder was 0.30–1 gram a day in 3 doses; the infusion (30 grams bark to 300 boiling water), 90 grams a day in 3 doses. Combined with opium it had more pronounced diaphoretic effects than the compounds of opium and ipecac. The plant possesses no febrifuge properties.
Botanical Description.—A tree, 5–6 meters high, trunk straight, hollow, the hollow space containing many thin partitions covered with small points; branches opposite. Leaves 4 times odd pinnate. Leaflets obliquely ovate, acute, entire, glabrous. Flowers in racemes with long, primary peduncles, large, fleshy, lurid, violet color, odor mawkish. Calyx inferior, cylindrical, monophyllous, entire. Corolla much longer than calyx, fleshy, bell-shaped, 5-lobed. Stamens 5, all fertile, fixed on the corolla, nearly equal in height. Style longer than stamens, flattened. Stigma cleft in 2 flat leaves. Silique or pod about 3° long and 2′ wide, flattened, borders grooved and curved downward, containing a great number of seeds encircled by a broad, flat, imbricated wing.
Habitat.—Common in many parts of Luzon, in Mindanao, Cebú and Paragua.
Pedaliaceæ.
Pedalium Family.
Sesamum Indicum, L.
Nom. Vulg.—Ajonjoli, Sp.; Lig̃á, Tag.; Log̃á, Vis.; Lag̃is, Pam.; Sesamé, Indo-Eng. (Benné Oil, Til Oil, Jinjili Oil.)
Uses.—The leaves are emollient and in the Philippines, India and the Southern States of North America they are commonly used to make poultices, as a substitute for linseed.
The decoction is prescribed internally as an emmenagogue and demulcent and externally as a lotion. It has the reputation of stimulating the growth of the hair and is used for this purpose quite commonly by the women of India.
The seeds are emollient, laxative, diuretic and emmenagogue; they contain an oil to which we shall refer presently. In some countries they form an article of diet; in the Philippines they are much used as a condiment. Waring reports good results in amenorrhœa, adding a handful of the bruised seeds to a hot sitz-bath. Two or 3 dessert-spoonfuls of the seeds eaten fasting and washed down with a glass of water, are very efficient in chronic constipation, both by their mechanical effect and the oil they contain; being non-irritant they are especially indicated in cases of constipation with hemorrhoids.
The seeds contain up to 45% of oil known in the Philippines under the name of lana, an Ilocano word meaning “oil.” It is bright yellow, viscid, does not easily become rancid and is used for illuminating purposes in some Philippine provinces. In Japan and among the poor of India it serves as a food; in the latter country it is also very commonly used as a cosmetic, perfumed with various essences and used to anoint the hair and the body after the bath. In America it is given in place of castor oil in doses of 30–60 grams. In pharmacy it may be properly substituted for olive oil, especially in Linimentum Calcis prepared for burns.
Botanical Description.—A plant 2–4° high, stem straight, square, grooved. Leaves trifoliate. Leaflets lanceolate, serrate, slightly downy. Common petiole long; secondary petiole very short. Flowers pinkish white, in spikes, each flower bearing 2 small glands. Calyx with 2 bracts at the base, top-shaped, monophyllous, 5 lanceolate teeth. Corolla large, 5-lobed, bell-shaped, expanded in the middle where it is spattered with small spots. Stamens didynamous. Anthers long. Ovary downy, quadrangular. Style same length as stamens. Stigma bifid. Seed vessel quadrangular, elongated, 4 opposite grooves, 4 chambers each containing many small ovoid seeds.
Habitat.—Universal. Blooms in October.
Acanthaceæ.
Acanthus Family.
Acanthus ilicifolius, L.
Nom. Vulg.—Diliwariw, Dolo-ariw, Tig̃log, Lagiwlagiw, Tag.; Titiw, Vis.; Dulawari, Pam.
Uses.—We are not familiar with the medicinal uses of this plant in the Philippines, but believe that its sole use is in the soap-making industry; the ash of the plant is rich in soda and potash salts and lye is prepared from it.
In Goa the leaves, rich in mucilage, are used locally in fomentations for rheumatism and neuralgia. Rheede mentions as useful the application of the bruised sprouts to snake bites. Bontius attributes expectorant properties to the plant. The natives of Siam and Cochin China use it as a cordial and as a medicine for paralysis and asthma.
In Concan the sweetened decoction of the plant with a little cumin seed is given for dyspepsia with pyrosis.
Botanical Description.—A plant about 3° high, stem straight, beset with sharp eminences. Leaves opposite, membranaceous, lanceolate, pinnatifid, large teeth ending in prickles. Petioles very short, 2 thorns at the base. Flowers purplish white in spikes. Calyx double; the outer one of 2 parts, the inner 4. Corolla bell-shaped, lower lip broad, keeled, fleshy, notched above. Upper lip wanting, a notch in its place. Stamens 4, didynamous. Ovary superior, conical. Style of equal length with stamens. Stigma bifid. Seed vessels 2-celled, each cell with 2 heart-shaped, flattened, rough seeds.
Habitat.—Very common in regions inundated by salt water.
Barleria Prionitis, L. (Barreliera Prionitis, Blanco.)
Nom. Vulg.—Kokog̃manok, Kulanta, Tag.
Uses.—This plant is not used medicinally in the Philippines. The natives of Bombay are accustomed to use its juice to anoint the soles of their feet during the rainy season in order to toughen the skin and prevent fissures due to prolonged maceration.
The leaf juice is bitter and acid; it is a favorite with the natives of India in the treatment of the catarrhal fevers common among their children, administered in doses of 2 tablespoonfuls a day mixed with sweetened water.
In Concan the dry bark is given for whooping-cough and the juice of the fresh bark in doses of 2 “tolas” (7.60 grams) for anasarca. Dr. Bidie states that the action is diaphoretic and expectorant.
Botanical Description.—A plant 2–3° high, stem creeping, the ends rising; enlarged at the joints, glabrous. Leaves smooth, opposite, lanceolate, finely serrate, fringed, somewhat downy below, glabrous above. Petioles short, 4 axillary spines. Flowers straw-color, axillary, sessile, solitary. Calyx deeply cleft in 4 parts, ovate, ending in spines. Corolla funnel-shaped, tube short, throat nude, limb 5-lobed. Stamens 4, didynamous. Ovary 2-celled. Style same length as stamens. Seed-vessel ovate, flattened and sharp-pointed, 2-celled, each cell with a flat, heart-shaped seed.
Habitat.—In Guadalupe, Mandaloyon and San Juan del Monte. Blooms in April.
Justicia Gendarussa, L. (Gandarussa vulgaris, Nees.; Dianthera subserrata, Blanco.)
Nom. Vulg.—Kapanitulot, Tag.; Bunlaw, Vis.
Uses.—In the Philippines this plant has the same applications as the Lagundi or Vitex, soon to be described. In India they give a decoction of the leaves for chronic rheumatism, the action probably being diaphoretic. The juice is employed for the coughs of childhood and externally as a resolvent for enlarged cervical glands. The bark of the young branches has a purplish color; in Java it is considered a good emetic.
Botanical Description.—A shrub 5–6° high, stem straight, branches smooth, obscurely 4-angled. Stems and leaves violet color, emitting a disagreeable odor (Blanco). Leaves opposite, lanceolate, acute, glabrous, obtusely serrate. Flowers terminal, white-green, in racemes of 3 sessile flowers with lanceolate bracts. Calyx, 5 long teeth. Corolla, short tube, 2-lipped, upper lip notched, lower lip broad with palate, ending in 3 lobules. Seed vessel with 4 seeds in its lower part.
Habitat.—Luzon, Mindanao, Panay.
Adhatoda vasica, Nees. (Justicia Adhatoda, L.)
Nom. Vulg.—(?)
Uses.—The Filipinos are but slightly familiar with this plant and it has no place in their therapeutical armamentarium. In India, however, it is very common and enjoys much reputation in the treatment of catarrhs, the grip, asthma and non-febrile, especially chronic, bronchial affections. The flowers, leaves and roots, but especially the flowers, possess antispasmodic properties and are prescribed in certain forms of asthma; they are bitter and slightly aromatic, and are given in infusion or electuary.
Drs. Jackson and Dott have testified from their own experience to the usefulness of the drug in chronic bronchitis, asthma and afebrile catarrh. Dr. Watt states that the natives of Bengal find relief for asthma in smoking the leaves. In Bombay its expectorant action is commonly known and its juice is used, mixed with borax and honey.
The dose of the aqueous extract made by evaporating the juice of the leaves, is .25–1 gram. The tincture is preferable, made by dissolving this extract in alcohol; dose 2–4 grams. Its efficiency is increased by the addition of pepper seeds (Waring). The Sanscrit writers recommend for cough, 3.80 grams of the leaf juice with honey. “It is very desirable that further trials be made to test the value of this remedy.”—Pharmacopœia of India.
Botanical Description.—A shrub with straight, smooth, ashy-gray trunk. Branches of same color but smoother. Leaves opposite, lanceolate, acute, smooth on both faces, 12–15 cm. long by 3–4 broad, petioles short. Flowers irregular and hermaphrodite in axillary spikes with long peduncles, opposite, large, white, covered with rusty spots, the lower part of the 2 lips purple. Calyx gamosepalous, regular, five deep clefts. Corolla gamopetalous, irregular, short tube, limb 2-lipped, the lower lip ending in a spur. Ovary free, 2-celled, each cell containing 2 ovules. Style filiform, long, inserted in a sort of canal formed by the upper lip of the corolla. Stigma bilobulate. Seed vessel depressed, 4 flattened, lenticular seeds.
Habitat.—Luzon and Panay.
Rhinacanthus communis, Nees. (Justicia nasuta, L.)
Nom. Vulg.—Tagaktagak, Tag.; Nagamulli, Indo-Eng.
Uses.—The plant has much reputation in India in the treatment of skin diseases, and indeed its efficiency is great in the stubborn Tinea circinata tropica, known throughout the Orient as “dhobie-itch.” In this disease it is applied for several days to the affected part in the form of a paste composed of the bruised leaves, the juice of the leaves and lemon juice. The fresh root also may be employed. The Hindoo physicians state that the root decoction in milk is aphrodisiac; the root is also regarded as an antidote for the bite of the “cobra da cabelho,” but its virtue is purely imaginary. Of late years the plant has been used in Europe under the name of “tong-pang-chong,” to treat chronic eczema.
Liborius made an analysis of the root in the laboratory of Dorpat, separating 13.51% ash and 1.87% rhinocanthin, as well as other ingredients. Rhinocanthin (C14H18O4) is supposed to be the active principle of the root. It is analogous to quinon and resembles in many particulars chrysophanic and frangulic acids. It forms a resinous, amorphous mass, cherry red, odorless and tasteless, slightly soluble in water, forming a mildly alkaline solution in alcohol. It does not yield glucose when boiled with dilute hydrochloric acid. Liborius believes that it exists only in the intercellular spaces of the “root bark.”
Botanical Description.—A shrub, about 4° high, stem ash-colored, no spines. Leaves lanceolate, undulate, downy. Flowers white in spikes. Calyx gamosepalous, 5-toothed. Corolla long, filiform, limb 4-lobed, the 3 lower lobes ovate, the upper pointed. Stamens 2. Ovary free, 2 biovulate locules. Style simple. Stigma bifid. Seed vessel club-shaped, 4 seeds in the upper part.
Habitat.—Common in the gardens of Manila.
Verbenaceæ.
Vervain Family.
Lippia nodiflora, Rich. (Verbena nodiflora, L.; V. capitata, Blanco.)
Nom. Vulg.—Tsatsatsatsahan, Chachachachahan, Tag.
Uses.—The Filipinos drink an infusion of the leaves in place of tea, the long Tagalog name meaning “resembling tea.” In India they drink the hot infusion to aid digestion. In some places the decoction of the leaves is given internally as an emollient and diuretic for gonorrhœa.
Botanical Description.—A small plant with creeping stem taking root where it touches the ground, obscurely angular, covered with short down. Leaves opposite, smooth, clasping the stem, inversely ovate, serrate only above, slightly downy. Flowers white, slightly purplish, axillary on a common peduncle, in a rough conical head. Corolla somewhat bowed, funnel-form, gaping, throat narrow, limb 4-lobed, one lobe shorter than the rest. Stamens 4, 2 longer. Filament almost wanting. Anthers 4, fertile. Ovary superior, style very short. Stigma semi-globose. Fruit, 2 seeds covered by the pellicle of the ovary.
Habitat.—Very common in the rice fields.
Tectona grandis, L.
Nom. Vulg.—Teca, Sp.; Tikla, Tag.; Dalondón, Yate, Kalayati, Vis.; Teak Tree, Eng.
Uses.—The powdered wood made into a paste with water is undoubtedly a useful application in acute dermatitis, especially that due to contact with the caustic oleo-resin of the cashew nut (Anacardium). A decoction of the powder gives good results as a gargle for aphthæ, gingivitis, and other inflammations within the buccal cavity. In India they give internally 6–12 grams as a vermifuge, and for dyspepsia with “heartburn.”
The flowers are diuretic according to Endlicher; the bark is astringent; the leaves and the seeds are purgative, the latter yielding an oil which they use in India to stimulate the growth of the hair. Gibson considers the seeds diuretic and quotes two cases where abundant diuresis immediately followed by the application of a poultice of the bruised seeds over the pubis. In Concan they make a sort of extract from the wood and apply it to the yoke sores of the cattle to prevent the growth of maggots. This disinfectant action marks the plant as worthy of further experiment.
Rumphius is authority for the statement that the infusion of the leaves is used in cholera. The Chinese make vessels of the wood to preserve their drinking water at sea; the first and second waters are bitter and are thrown away, but after that the water has no disagreeable taste and is said to aid digestion.
It has been said that the wood was poisonous because at one time several workmen died from the effects of wounds caused by splinters of the wood, but the statement has not been confirmed by later cases and the deaths were most probably due to a septic infection independent of the chemical composition of the splinters.
R. Romanis has extracted a resin from the wood by alcohol; it is soft, and on distillation yields a crystalline body called by the author tectoquinon (C18H10O2), on account of its resemblance to the quinons. It melts at 171° and volatilizes slightly at ordinary temperature.
Botanical Description.—A tree with leaves almost round, oval, entire, 30–60 centimeters by 20–40, the under surface covered with hoary down. Petioles very short, flattened. Flowers in panicles. Primary peduncle square. Calyx inferior, bell-shaped, very large when ripe, 5-cleft. Corolla white, longer than calyx, covered with a mealy substance, bell-shaped, 5-lobed. Stamens 5 or 6, inserted in the corolla. Filaments flattened, somewhat longer than the corolla. Anthers semi-globose, a yellow zone below and a black circle above. Ovary free, rounded, 4 locules each with 1 seed. Style same length as stamens. Stigma bilobulate. Drupe globose, woolly, spongy, depressed, covered by the membranous inflated calyx; contains one nut, very hard, 4 apartments each containing one seed.
Habitat.—The mountains of Morong and Tanay (of La Laguna Province) bear some specimens. Very common in the island of Negros and in Mindanao. It also grows in the Visayas, Mindora and Paragua. Blooms in September.
Vitex trifolia, L. (V. repens, Blanco.)
Nom. Vulg.—Lagundi, Tag.; Gapasgapas, Vis.; Dangla, Iloc.
Vitex Negundo, L. (V. Leucoxylon, Blanco.)
Nom. Vulg.—Lagundi, Malawin, Tag.
Uses.—Both species are used medicinally in the Philippines and both enjoy high repute. A variety of the first that seems to possess the same virtues is the V. repens, Blanco, called lagundig̃ gapag̃ by the Tagalos.
V. trifolia is regarded in India as the most powerful species and Bontius has extolled it highly, calling attention to the anodyne, diuretic and emmenagogue properties of the leaves. These are very effective applied in fomentation to rheumatic joints and their use is extensive both in India and the Malay Archipelago. A decoction of the leaves is used locally and as a vapor-bath in the treatment of beriberi. A large earthen pot is filled with leaves and water and brought to a boil; the pot is then placed under a chair in which the patient sits enveloped in a sheet or blanket. If necessary the pot may be removed 2 or 3 times, heated and replaced until abundant sweating is induced. An apparatus to conduct the steam under the chair would be much handier, but it is unsafe to place a small stove or lamp under the chair for fear of setting fire to the cloth.
In India and the Philippines there is a peculiar inflammation localized in the soles of the feet and characterized by an intense burning rather than pain, not described in the textbooks, but called by the natives “burning of the feet” (“quemadura del pié” or “ignipedites”); in our own experience and according to the consensus of the physicians of India, the application of these leaves 3 or 4 times a day to the soles of the feet has afforded marked relief. The leaves are heated in an earthen pot without the addition of water, and when sufficiently hot are applied and held in place by a bandage.
Dr. W. Ingledew states that the natives of Mysore (south of India) treat rheumatism and febrile catarrhs by steam baths of the decoction of vitex. A decoction of the leaves is in common use in the Philippines, Malay Islands and India as a bath for women in the puerperal state.
The dry leaves are smoked for headache and catarrh. According to creditable authority the application of the heated leaves in orchitis produces good results. The root is tonic, febrifuge and expectorant and the fruit nervine and emmenagogue according to the Sanscrit writer.
Botanical Description.—V. trifolia is a small tree, 3–4 meters high. The fruit and leaves are said to emit the odor of rosemary. Leaves ternate. Leaflets oval, entire, hoary below, no secondary petioles. Flowers purplish in forked panicle. Corolla bell-shaped with palate. The lower lip 3-lobed, the middle lobe larger; upper lip smaller, 2-lobed. Stamens 4, free, didynamous. Ovary free. Style simple, with stigma-bearing lobules. Berry-like drupe, with 4-celled nut, one seed in each cell.
Habitat.—Common on the seashore. Blooms in June.
The V. Negundo is a small tree like the preceding, but when it grows in the forest it develops to a tree of the first order, yielding a valuable building wood called molave (Sp.) or more properly molawin. Leaves compound with 5 leaflets. Secondary petioles short. Flowers in dichotomous panicle. Fruit like that of the foregoing species.
Clerodendron infortunatum, L. (C. fortunatum, Blanco.)
Nom. Vulg.—Kasupag̃it, Gubat, Tag.; Salig̃-wak, Vis.
Uses.—The fresh juice of the leaves is used in India as a vermifuge, according to K. L. Dey; it is also used as a bitter tonic in malarial fever, especially of children. As a tonic and antipyretic it is certainly worthy of recommendation.
Dr. Bholanauth Bose calls attention to this plant as a good substitute for Ophelia chirata, DC. as a tonic and antipyretic.
The infusion of the bruised leaves (10 grams to water 300 cc.) is given up to 200 cc. a day in 3 or 4 doses; the tincture (leaves 60 grams, alcohol 90 %, 500 cc.) is given up to 10 grams a day in 5 or 6 doses.
Botanical Description.—A shrub with nearly round stem; leaves opposite, ovate, oblong; acute, entire, slightly downy. Flowers terminal in umbellate panicles, the umbellets opposite and each bearing 3 flowerets. Calyx bluish, long, tubular, somewhat expanded in the middle, divided in 5 parts. Corolla twice as long as the calyx, tube filiform, limb 5-lobed. Stamens didynamous, their lower parts grown to the tube of the corolla. Filaments longer than the corolla. Ovary conical. Style of same length as the stamens. Stigma bifid. Berry dry, quadrate, depressed, the shell hard, 4 grooves, 4 cells, each containing a seed.
Habitat.—Very common in Manila and in the forests.
Labiatæ.
Mint Family.
Ocimum basilicum, L. (O. Americanum, Blanco.)
Nom. Vulg.—Solasi, Tag., Pam.; Bonak, Vis.; Sweet Basil, Eng.
Ocimum gratissimum, L. (O. virgatum Blanco.)
Nom. Vulg.—Lokoloko, Tag., Pam.; Kolonkogon, Vis.
Ocimum sanctum, L. (O. flexuosum, Blanco.)
Nom. Vulg.—Balanay, Tag.; Sacred Basil, Eng.
Uses.—All three species possess a characteristic camphoraceous odor and are commonly grouped under the one name, albahacas (sweet basil). Some natives call them solasi and others balanay, but many are able to distinguish the various species correctly. All three have analogous properties, but the most widely used is the O. basilicum. These properties are stimulant, diaphoretic, and expectorant, and the infusion is used commonly for flatulent colic and painful dyspepsia. The dry powdered leaves of the O. sanctum are taken as snuff by the natives of India in the treatment of a curious endemic disease characterized by the presence of small maggots in the nasal secretion; this disease is called peenash, and possibly exists in the Philippines though I have never encountered it.
Martins states that in Brazil they use a decoction of the mucilaginous leaves of the O. gratissimum in the treatment of gonorrhœa and Dr. Waitz highly recommends a strong decoction of these leaves for the aphthæ of children, which he claims to have cured by this means after all European drugs had failed. This fact and the action of the snuff above mentioned, demonstrate the antiseptic properties of the plant, due doubtless to its abundant aromatic principles.
O. basilicum contains a green essential oil, very aromatic, becoming solid; it is a sort of camphor (C20H166HO, Raybaud) and crystallizes in 4-faced prisms.
All the plants are used to prepare aromatic baths for cases of atrophy and debility in children (Waitz) and for the treatment of rheumatism and paralysis.
Botanical Description.—O. gratissimum is a plant 2–3° high, stem straight, downy. Leaves medium lanceolate, finely serrate from the middle upwards, with short hairs and transparent dots. Flowers in long terminal racemes. Calyx, upper lip horizontal, round; lower lip 3 pointed parts, the middle one subdivided in two. Corolla yellowish, inverted, one lip cleft in 4 obtuse lobes; the other longer, narrow, serrate. Stamens didynamous, 2 shorter. Anthers semilunar. Stigma bifid. Seeds 4.
The O. Americanum has leaves lanceolate, ovate, acute, full of pores, somewhat downy. It is more fragrant than the other species and its flowers are bluish-white in racemes.
The O. sanctum is the most sacred plant of the Hindoos, dedicated to Vishnu; its branches are wavy or cauliflexuous, leaves obliquely ovate, obtuse, serrate, nearly glabrous.
Habitat.—All species are very common and universally known.
Coleus aromaticus, Benth. (C. suganda, Blanco.)
Nom. Vulg.—Orégano, Sp.-Fil.; Suganda, Tag.; Marjoram, Eng. (The Sp. and Eng. names are incorrect.)
Uses.—The fleshy, aromatic leaves of this plant are bruised and applied locally for the bites of centipedes and scorpions. They are also applied to the temples and forehead for headache, held in place by a bandage. In Cochin China they are used in asthma, chronic bronchitis, epilepsy and other convulsive diseases. The juice of the leaves is a carminative and is given to children suffering with wind colic. Dr. Wight claims to have observed occasional intoxicating effects following its use, but Dymock states that he has never observed such effects. The plant contains a coloring matter, colein (C10H10O3), red, insoluble in ether, soluble in alcohol, slightly soluble in water. On the addition of ammonia the solution changes to purple, then violet, indigo, green, and, finally, greenish-yellow.
Another species, the C. atropurpureus, Benth. (C. grandifolius, Blanco), well known in the Philippines by its common name mayana, is used in the treatment of bruises, the bruised fleshy leaves being the part employed; these leaves are downy and dark violet in color.
Botanical Description.—Leaves opposite, nearly sessile, cordate, obtuse, downy and very fleshy. Flowers in a quadrangular raceme, each group of these flowerets having a concave scale at the base. Calyx bell-shaped, 2-lipped; the upper lip longer and entire; the lower with 4 narrow teeth. Corolla a pale violet, 5 times longer than the calyx. Stamens didynamous, straight, longer than the corolla. Style bifid. Seeds 4.
Habitat.—Universally abundant.
Rosmarinus officinalis, L.
Nom. Vulg.—Romero, Sp.; Rosemary, Eng.
Uses.—This is one of the plants most valued by the Filipinos. Its infusion is used as an eye-wash for slight catarrhal conjunctivitis, applied 3 or 4 times a day. It is one of the aromatic plants used so commonly to bathe women in the puerperal state, and in vapor baths for rheumatism, paralysis and incipient catarrhs. The entire plant is a stimulant and carminative but little used internally; in atonic dyspepsia it has given good results taken in the same form as the infusion of manzanilla.
It contains a large per cent. of an essential oil which gives the plant its agreeable odor. This oil enters into the composition of “Cologne Water”; it is said to arrest falling of the hair and is a diffusible stimulant which may be given internally in doses of 3–5 drops. It is colorless and liquid when fresh, but in time becomes dark and viscid. It combines freely with alcohol and its density is 0.885.