I.—PHÆNOGAMOUS OR FLOWERING PLANTS. (continued 15)

In var. 2. vulgaris of Sole, M. piperita β. Smith, the plant is more hairy, with the spikes broader and shorter, or even bluntly capitate. colourless, pale yellow, or greenish liquid, of sp. gr. varying from 0·84 to 0·92. We learn from information kindly supplied by Messrs. Schimmel and Co., Leipzig, that the best peppermint grown in Germany, carefully dried, affords from 1 to 1·25 per cent. of oil. It has a strong and agreeable odour, with a powerful aromatic taste, followed by a sensation of cold when air is drawn into the mouth. We find that the Mitcham oil examined by polarized light in a column 50 mm. long, deviates from 14°·2 to 10°·7 to the left, American oil 4°·3.

Chemical Composition—The constituent for the sake of which peppermint is cultivated is the essential oil, Oleum Menthæ piperitæ, a coloureless, pale yellow or greenish liquid, of sp. gr. varying from 0·84 to 0·92. We learn from information kindly supplied by Messrs. Schimmel and Co., Leipzig, that the best peppermint grown in Germany, carefully dried from 1 to 1·25 per cent of oil. It has a strong and agreeable odour, with a powerful aromatic taste, followed by a sensation of cold when air is drawn into the mouth. We find that the Mitcham oil examined by polarized light in a column 50 mm. long, deviates from 14·2° to 10·7° to the left, American oil 4·2°.

When oil of peppermint is cooled to -4° C., it sometimes deposits colourless hexagonal crystals of Peppermint Camphor, C₁₀H₁₉OH, called also Menthol. We have never observed it, nor are we aware that menthol has been noticed in America, but it is largely afforded by eastern mints, and found in commerce under the name of Chinese or Japanese Oil of Peppermint,[1770] either liquid, and easily depositing the camphor, or also forming a crystalline mass impregnated with the liquid oil.

Pure menthol has the exquisite odour and taste of peppermint; it forms hexagonal crystals, melting at 42° C., and boiling at 212° C. By distilling menthol with P₂O₅ it yields menthene, C₁₀H₁₈, a levogyrate liquid, boiling at 163°, the peculiar odour of which reminds of peppermint.[1771] The Chinese crystallized oil of peppermint has sometimes a bitterish after-taste and an odour similar to that of spearmint, but by recrystallization it assumes the pure flavour.

The liquid part of the oil of peppermint has not yet been thoroughly investigated; it appears to consist chiefly of the compound C₁₀H₁₈O. Upon the liquid portions depend the remarkable colorations which the oil of peppermint is capable of assuming. If 50 to 70 drops of the crude oil are shaken with one drop of nitric acid, sp. gr. about 1·2, the mixture changes from faintly yellowish to brownish, and, after an hour or two, exhibits a bluish, violet or greenish colour; in reflected light, it appears reddish and not transparent. The colour thus produced lasts a fortnight. We have thus examined the various samples of peppermint oil at our command, and may state that the finest among them assume the most beautiful coloration and fluorescence, which, however, shows very appreciable differences. An inferior oil of American origin was not coloured; and a very old sample of an originally excellent English oil was likewise not coloured by the test. Menthol is not altered when similarly treated.[1772] The nitric acid test is not capable of revealing adulterations of peppermint oil, for the coloration takes place with an oil to which a considerable quantity of oil of turpentine has been added.

Remarkable colorations of a different hue are also displayed by the various kinds of oil of peppermint if other chemical agents are mixed with it. Thus green or brownish tints are produced by means of anhydrous chloral; the oil becomes bluish or greenish or rose-coloured if shaken with a concentrated solution of bisulphite of sodium. It is worthy of note that oils of different origin, which cannot be distinguished by means of nitric acid, exhibit totally different colorations if mixed with either of the liquids just named, or with vapour of bromine. This behaviour may be of some use in the examination of commercial sorts of peppermint oil.

As to bisulphite of sodium, it yields a solid compound with certain kinds of peppermint oil, which we have not yet examined.

Production and Commerce—In several parts of Europe, as well as in the United States, peppermint is cultivated on the large scale as a medicinal plant.

In England the culture is carried on in the neighbourhood of Mitcham in Surrey, near Wisebeach in Cambridgeshire, Market Deeping in Lincolnshire, and Hitchin in Hertfordshire.

At Mitcham in 1850 there were about 500 acres under cultivation; in 1864 only about 219 acres.[1773] At Market Deeping there were in 1871 about 150 acres cropped with peppermint. The usual produce in oil may be reckoned at 8 to 12 lb. per acre. The fields of peppermint at Mitcham are level, with a rich, friable soil, well manured and naturally retentive of moisture. The ground is kept free from weeds, and in other respects is carefully tilled. The crop is cut in August, and the herb is usually allowed to dry on the ground before it is consigned to the stills. These are of large size, holding 1000 to 2000 gallons, and heated by coal; each still is furnished with a condensing worm of the usual character, which passes out into a small iron cage secured by a padlock, in which stands the oil separator. The distillation is conducted at the lowest possible temperature. The water that comes over with the oil is not distilled with another lot of herb, but is for the most part allowed to run away, a very little only being reserved as a perquisite of the workmen. The produce is very variable, and no facilities exist for estimating it with accuracy.[1774] It is however stated that a ton of dried peppermint yields from 2½ to 3½ pounds of oil, which equals 0·11 to 0·15 per cent. But we have been assured by a grower at Mitcham that the yield is as much as 6 pounds from a ton, or 0·26 per cent.

At Mitcham and its neighbourhood two varieties of peppermint are at present recognized, the one being known as White Mint, the other as Black Mint, but the differences between the two are very slight. The Black Mint has purple stems; the White Mint, green stems, and as we have observed, leaves rather more coarsely serrated than those of the Black. The Black Mint is more prolific in essential oil than the White, and hence more generally cultivated; but the oil of the latter is superior in delicacy of odour and commands a higher price. White Mint is said to be principally grown for drying in bundles, or as it is termed “bunching.”

Peppermint is grown on a vastly larger scale in America, the localities where the cultivation is carried on being Southern Michigan, Western New York, and Ohio. In Michigan where the plant was introduced in 1855, there were in 1858 about 2100 acres devoted to its growth, all with the exception of about 100 acres being in the county of St. Joseph, where there are about 100 distilleries. The average produce of this district was estimated in 1858 at 15,000 lb.; but the yield fluctuates enormously, and in the exceptionally fine season of 1855 it was reckoned at 30,000 lb. We must suppose that it is sometimes much larger, for we have been informed by Mr. H. G. Hotchkiss, of Lyons, Wayne County, State of New York, one of the most well-known dealers, in a letter under date Oct. 10, 1871, that the quantity sent out by him in the previous year reached the enormous amount of 57,365 lb. It is further stated by the official statistics of Hamburg for the year 1876 that this port received 25,840 lb. of peppermint oil from the United States and 14,890 lb. from Great Britain.

From the statistics quoted by Stearns[1775] it would appear that the produce of oil per acre is somewhat higher in America than in England, but from various causes information on this head cannot be very reliable.

Peppermint is cultivated at Sens in the department of the Yonne in France[1776] and in Germany in the environs of Leipzig, where the little town of Cölleda produces annually as much as 40,000 cwts. of the herb.

The annual crop of the world is supposed to yield 90,000 lb. of peppermint oil.[1777]

Peppermint oil varies greatly in commercial value, that of Mitcham commanding twice or three times as high a price as the finest American. Even the oil of Mitcham is by no means uniform in quality, certain plots of ground affording a product of superior fragrance. A damp situation or badly drained ground is well known to be unfavourable to the quantity and quality of oil.

The presence of weeds among the peppermint is an important cause of deterioration to the oil, and at Mitcham some growers give a gratuity to their labourers to induce them to be careful in throwing out other plants when cutting the herb for distillation. One grower of peppermint known to us was compelled to abandon the cultivation, owing to the enormous increase of Mentha arvensis L. which could not be separated, and which when distilled with the peppermint ruined the flavour of the latter. In America great detriment is occasioned by the growth of Erigeron canadensis L. Newly cleared ground planted with peppermint is liable to the intrusion of another plant of the order Compositæ, Erechtites hieracifolia Raf., which is also highly injurious to the quality of the oil.[1778]

Uses—A watery or spirituous solution of oil of peppermint is a grateful stimulant, and is a frequent adjunct to other medicines. Oil of peppermint is extensively consumed for flavouring and cordials.

HERBA PULEGII.

Pennyroyal[1779]; F. Menthe pouliot, Pouliot vulgaire; G. Polei.

Botanical Origin—Mentha Pulegium L., a small perennial aromatic plant, common throughout the south of Europe and extending northward to Sweden, Denmark, England and Ireland, eastward to Asia Minor and Persia, and southward to Abyssinia, Algeria, Madeira and Teneriffe. It has been introduced into North[1780] and South America. For medicinal use it is cultivated on a small scale.

History—Pennyroyal was in high repute among the ancients. Both Dioscorides and Pliny describe its numerous virtues. In Northern Europe it was also much esteemed, as may be inferred from the frequent reference to it in the Anglo-Saxon and Welsh works on medicine.

Gerarde considered the plant to be “so exceedingly well known to all our English nation” that it needed no description. In his time (circa 1590), it used to be collected on the commons round London, whence it was brought in plenty to the London markets. At the present day pennyroyal has fallen into neglect, and is not named in the British Pharmacopœia of 1867.

Description—The plant has a low, decumbent, branching stem, which in flowering rises to a height of about 6 inches. Its leaves, scarcely an inch in length and often much less, are petiolate, ovate, blunt, crenate at the margin, dotted with oil-glands above and below. The flowers are arranged in a series of dense, globose whorls, extending for a considerable distance up the stem. The whole plant is more or less hairy. It has a strong fragrant odour, less agreeable to most persons than that of peppermint or spearmint. Its taste, well perceived in the distilled water, is highly aromatic.

Chemical Composition—The most important constituent of pennyroyal is the essential oil, known in pharmacy as Oleum Pulegii, to which is due the odour of the plant. It has been examined by Kane,[1781] according to whom it has a sp. gr. of 0·927. Its boiling was found to fluctuate between 183° and 188° C. The formula assigned to it by this chemist is C₁₀H₁₆O. We ascertained that it contains no carvol (see page 481.)

Production—Pennyroyal is cultivated at Mitcham and is mostly sold dried; occasionally the herb is distilled for essential oil. The oil found in commerce is however chiefly French or German, and far less costly than that produced in England.

Uses—The distilled water of pennyroyal is carminative and antispasmodic, and is used in the same manner as peppermint water.

HERBA THYMI VULGARIS.

Garden Thyme; F. Thym vulgaire; G. Thymiankraut.

Botanical Origin—Thymus vulgaris L., a small, erect, woody shrub reaching 8 to 10 inches in height, gregarious on sterile uncultivated ground in Portugal, Spain, Southern France and Italy, and in the mountainous parts of Greece. On Mont Ventoux near Avignon, it reaches an elevation above the sea of 3700 ft. (Martins). It is commonly cultivated in English kitchens as a sweet herb,[1782] and succeeds as an annual even in Iceland.

History—We are not aware that thyme had any reputation in the antiquity, nor do we know at what period it was first introduced in northern countries. Garden thyme was commonly cultivated in England in the 16th century, and was well figured and described by Gerarde. It is even said to have been formerly grown on a large scale for medicinal use in the neighbourhood of Deal and Sandwich in Kent.[1783] Camphor of Thyme was noticed by Neumann, apothecary to the Court at Berlin in 1725;[1784] it was called Thymol, and carefully examined in 1853 by Lallemand, and recommended instead of phenol (carbolic acid) in 1868 by Bouilhon, apothecary, and Paquet, M. D. of Lille.

Description—The plant produces thin, woody, branching stems, bearing sessile, linear-lanceolate, or ovate-lanceolate leaves. These are about ¼ of an inch long, revolute at the margin, more or less hoary, especially on the under side, and dotted with shining oil-glands. The small purple flowers are borne on round terminal heads, with sometimes a few lower whorls. The entire wild plant has a greyish tint by reason of a short white pubescence, yet as seen in gardens the plant is more luxuriant, greener and far less tomentose. It is extremely fragrant when rubbed, and has a pungent aromatic taste.

Production of Essential Oil—Though cultivated in gardens for culinary use, common thyme is not grown in England on a large scale. Its essential oil (Oleum Thymi), for which alone it is of interest to the druggist, is distilled in the south of France. In the neighbourhood of Nîmes, where we have observed the process, the entire plant is used, and the distillation is carried on at two periods of the year, namely in May and June when the plant is in flower, and again late in the autumn. The oil has a deep, reddish-brown colour, but becomes colourless though rather less fragrant by re-distillation. The two sorts of oil, termed respectively Huile rouge de Thym and Huile blanche de Thym, are found in commerce. The yield is about 1 per cent.

Oil of thyme is frequently termed in English shops Oil of Origanum, which it in no respect resembles, and which was never, so far as we know, found in commerce.[1785]

Chemical Composition—The only constituent of the herb that has attracted any attention is the above-named essential oil. This liquid by fractional distillation is resolved into two portions: the first, more volatile and boiling below 180° C., is a mixture of two hydrocarbons, Cymene, C₁₀H₁₄ (see page 333), and Thymene, C₁₀H₁₆, the latter boiling at 165° C.

The second, named Thymol, C₁₀H₁₄O, which may also be extracted from the crude oil by means of caustic lye, has been described in our article Fructus Ajowan, at page 303. Commercial oil of thyme is said to be sometimes fraudulently deprived of thymol by that treatment.

Uses—Oil of thyme is an efficient external stimulant, and is sometimes employed as a liniment. Its chief consumption is in veterinary medicine. Thymol has been proposed as a disinfectant in the place of carbolic acid, in cases in which the odour of the latter is objectionable. The herb is not used in modern English medicine, but is often employed on the Continent.

HERBA ROSMARINI.

Herba Anthos; Rosemary; F. Romarin; G. Rosmarin.

Botanical Origin—Rosmarinus officinalis L., an evergreen shrub, attaining a height of 4 feet or more, abundant on dry rocky hills of the Mediterranean region, from the Spanish peninsula[1786] to Greece and Asia Minor. It generally prefers the neighbourhood of the sea, but occurs even in the Sahara, where it is collected and conveyed by caravans to Central Africa.[1787] It does not succeed well in Germany.

History—Rosemary[1788] is mentioned by Pliny, who ascribes to it numerous virtues. It was also familiar to the Arab physicians of Spain, one of whom, Ibn Baytar (13th cent.), states it to be an object of trade among the vendors of aromatics.[1789] In the middle ages rosemary was doubtless much esteemed, as may be inferred from the fact that it was one of the plants which Charlemagne ordered to be grown on the imperial farms.

It was probably in cultivation in Britain prior to the Norman Conquest, as it is recommended for use in an Anglo-Saxon herbal of the 11th century.[1790] In the “Physicians of Myddvai” a curious chapter[1791] is devoted to the virtues of Rosemary, called “Ysbwynwydd, and Rosa Marina in Latin.” The essential oil was distilled by Raymundus Lullus[1792] about a.d. 1330. John Philip de Lignamine,[1793] a writer of the 15th century, describes Rosemary as the usual condiment of salted meats.

Description—Rosemary has sessile, linear, entire, opposite leaves about an inch in length, revolute at the margin; they are of coriaceous texture, green and glabrous above, densely tomentose and white beneath. Examined under a lens, the tomentum both of the leaves and young shoots is seen to consist of white stellate hairs; in that of the shoots which is less dense, minute oil-glands are discernible. These glands are of two kinds, large and small, and probably do not yield one and the same oil. The flowers have a campanulate 2-lipped calyx, and a pale blue and white corolla, the upper lip of which is emarginate and erect, the lower 3-lobed with the central lobe concave and pendulous. The whole plant has a very agreeable smell and a strong aromatic taste. It flowers in the early spring.

Production of Essential Oil—Rosemary is cultivated on a very small scale in English herb-gardens, and though a little oil has been occasionally distilled from it, English oil of rosemary is an article practically unknown in commerce. That with which the market is supplied is produced in the south of France and on the contiguous coasts of Italy. The plant, which is plentifully found wild, is gathered in summer (not while in flower) and distilled, the operator being sometimes an itinerant herbalist who carries his copper alembic from place to place, erecting it where herbs are plentiful, and where a stream of water enables him to cool a condenser of primitive construction.

Oil of rosemary is also produced on a somewhat large scale in the island of Lesina, south of Spalato in Dalmatia, whence it is exported by way of Trieste, even to France and Italy, to the extent of 300 to 350 quintals annually.[1794]

Some of the French manufacturers of essences offer oil of rosemary at a superior price as drawn from the flowers, by which we presume is meant the flowering tops, for the separation of the actual flowers would be impracticable on a large scale. The great bulk of the oil found in commerce is however that distilled from the entire plant.

Chemical Composition—The peculiar odour of rosemary depends on the essential oil, which is the only constituent of the plant that has afforded matter for chemical research.

Lallemand (1859) by fractional distillation, resolved oil of rosemary into two liquids,—the one a mobile hydrocarbon boiling at 165° C. and turning the plane of polarization to the left; the other, boiling between 200° and 210° C., deposits when exposed to a low temperature a large quantity of camphor. Gladstone (1864) found the oil to consist almost wholly of a hydrocarbon, C₁₀H₁₆. This, according to our experiments, constitutes about ⁴/₅ of the oil; it deviates the plane of polarization to the left, whereas a fraction boiling at 200° to 210° C. deviates to the right. By warming the latter with nitric acid, we observed the odour of common camphor, and may therefore infer that a compound, C₁₀H₁₈O, is present in the oil under examination.

From Montgolfier’s investigations (1876) it would appear that the stearoptene or camphor above alluded to is a mixture of a dextrogyrate and a lævogyrate substance.

Uses—The flowering tops and dried leaves are kept by the herbalists, but are not used in regular medicine. The volatile oil is employed as an external stimulant in liniments, and also as a perfume. Rosemary is popularly supposed to promote the growth of the hair.

PLANTAGINEÆ.

SEMEN ISPAGHULÆ.

Ispaghúl Seeds, Spogel Seeds.

Botanical Origin—Plantago decumbens Forsk. (P. Ispaghula Roxb.),[1795] a plant of variable aspect, from an inch to a foot in height, erect or decumbent, with linear lanceolate leaves which may be nearly glabrous, or covered with shaggy hairs. The flower-spikes differ according to the luxuriance of the plant, being in some specimens cylindrical and 1½ inches long, in others reduced to a globular head. The plant has a wide range, occurring in the Canary Islands, Egypt, Arabia, Beluchistan, Afghanistan, and North-western India. Stewart[1796] says it is common in the Peshawar valley and Trans-Indus generally up to 2000 feet; also on the plains and lower hills of the Punjab, but that he has never seen it cultivated in the latter region. It is said to be cultivated at Multan and Lahore, also in Bengal and Mysore.

History—The seeds which are found in all the bazaars of India and are held in great esteem, are generally designated by the Persian word Ispaghúl; but they also bear the Arabic name Bazre-qatúná, under which we find them mentioned by the Persian physician Alhervi[1797] in the 10th century, and about the same period or a little later by Avicenna.[1798] Several other Oriental writers are quoted by Ibn Baytar[1799] as referring to a drug of the same name, which may possibly have included the seeds of other species, as Plantago Psyllium L. and P. Cynops, having similar properties, and known to have been used from an early period.

J. H. Linck, whom we mentioned in our article on Oleum Cajuputi (p. 278), described in 1719 the seed under notice, yet without knowing its name; it further attracted the notice of Europeans towards the close of the last century,[1800] and has been often prescribed as a demulcent in dysentery and diarrhœa. It was admitted to the Pharmacopœia of India of 1868.

Description—The seeds, like those of other species of Plantago, are of boat-shaped form, the albumen being deeply furrowed on one side and vaulted on the other. They are a little over ⅒ of an inch in length and nearly half as broad, and so light that 100 weigh scarcely three grains. Their colour is a light pinkish grey with an elongated brown spot on the vaulted back, due to the embryo, which at this point is in close contact with the translucent testa. From this brown spot the thick radicle runs to the top of the seed. The hollow side of the seed is also brown and partially covered with a thin white membrane.

The seeds are highly mucilaginous in the mouth, but have neither taste nor odour. Those of the allied P. Psyllium have nearly the same form, but are shining and of a dark brown hue.

Microscopic Structure—This can be best investigated by immersing the seed in benzol, as in this medium the mucilage is insoluble. When thus examined, the whole surface is seen to consist of polyhedral cells, separated by a very thin brown layer from the albumen, which on the back of the seed is only 70 mkm. thick. The albumen is made up of thick-walled cells, loaded with granules of matter which acquire an orange hue on addition of iodine. The two cotyledons adhere in a direction perpendicular to the bottom of the furrow; their tissue is composed of thin-walled smaller cells, containing also albuminous granules and drops of fatty oil.

If the seed is immersed in water, the cells composing the epidermis instantly swell and elongate, and soon burst, leaving only fragments of their walls. When examined under glycerin, the change is more gradual, and the outer walls of the cells yielding the mucilage display a series of thin layers, which slowly swell and disappear by the action of water. The mucilage is consequently not contained within the cells, but is formed of the secondary deposits on their walls, as in linseed and quince pips.

Chemical Composition—Mucilage is so abundantly yielded by these seeds, that one part of them with 20 parts of water forms a thick tasteless jelly. On addition of a larger quantity of water and filtering, but little mucilage passes, the greater part of it adhering to the seeds. The mucilage separated by straining with pressure does not redden litmus, is not affected by iodine, nor precipitated by borax, alcohol or ferric chloride. The fat oil and albuminous matter of the seed have not been examined.

Uses—A decoction of the seeds (1 p. to 70 p. of water) is employed in India as a cooling, demulcent drink. The seeds powdered and mixed with sugar, or made gelatinous with water, are sometimes given in chronic diarrhœa.

POLYGONACEÆ.

RADIX RHEI.

Rhubarb; F. Rhubarbe; G. Rhabarber.

Botanical Origin—No competent observer, as far as we know, has ever ascertained as an eye-witness the species of Rheum which affords the commercial rhubarb. Rheum officinale, from which it seems, at least partly, derived is the only species yielding a rootstock which agrees with the drug.

Rheum officinale Baillon is a perennial noble plant resembling the Common Garden Rhubarb, but of larger size. It differs from the latter in several particulars: the leaves spring from a distinct crown rising some inches above the surface of the ground; they have a subcylindrical petiole, which as well as the veins of the under side of the lamina is covered with a pubescence of short erect hairs. The lamina, the outline of which is orbicular, cordate at the base, is shortly 5-to 7-lobed, with the lobes coarsely and irregularly dentate; it attains 4 to 4½ feet in length and rather more in breadth. The first leaves in spring display before expanding the peculiar metallic red hue of copper.

The plant was discovered in South-eastern Tibet, where it is said to be often cultivated for the sake of its medicinal root; but it is supposed to grow in various parts of Western and North-western China, whence the supplies of rhubarb are derived. It was obtained by the French missionaries about the year 1867 for Dabry, French Consul at Hankow, who transmitted specimens to Dr. Soubeiran of Paris. From one of these which flowered at Montmorency in 1871, a botanical description was drawn up by Baillon.[1801]

To what extent the rhubarb of commerce is derived from this plant is not known. But that the latter may be a true source of the drug is supported by the fact, that there is at least no important discrepancy between it and the accounts and figures, scanty and imperfect though they are, given by Chinese authors and the old Jesuit missionaries; and still more by the agreement in structure which exists between its root and the Asiatic rhubarb of commerce.

We have engaged in 1873 Mr. Rufus Usher at Bodicott (see below, p. 500) to cultivate Rheum officinale, which is there admirably succeeding; but it must be granted that as yet the root, notwithstanding the most careful preparation in drying it, is far from displaying the rich yellow of the commercial drug. It is most obviously marked on the other hand with the characteristic ring of stellate markings, which we have constantly observed in many roots of Rheum officinale cultivated by us at Clapham Common near London, as well as at Strassburg or, by other observers, at Paris.

Rheum palmatum L., a species known as long as 1750, has always been supposed to yield also rhubarb, and this has again been asserted by the Russian Colonel Przewalski, who observed in 1872 and 1873 that plant in the Alpine parts of Tangut round the Lake Kuku-nor, in the Chinese province of Kansu, in 36°-38° North Lat.—Rheum palmatum has been frequently cultivated in Russian Asia and in many parts of Europe since the last century, but without producing a root agreeing with Chinese rhubarb. Now, Przewalski states that from this species the drug under notice is largely collected along the river Tetung-gol (or Datung-ho), a tributary of the upper Hoang-ho, northward of the Kuku-nor. Specimens of that root were largely brought to St. Petersburg by Przewalski, but Dragendorff expressly points out in his Jahresbericht for 1877 (p. 78) that it is dissimilar to true rhubarb.

History[1802]—The Chinese appear to have been acquainted with the properties of rhubarb from a period long anterior to the Christian era, for the drug is treated of in the herbal called Pen-king, which is attributed to the Emperor Shen-nung, the father of Chinese agriculture and medicine, who reigned about 2700 b.c. The drug is named there Huang-liang, yellow, excellent, and Ta-huang, the great yellow.[1803] The latter name also occurs in the great Geography of China, where it is stated that rhubarb was a tribute of the province Si-ning-fu, eastward of Lake Kuku-nor,[1804] from about the 7th to the 10th centuries of our era.

As regards Western Asia and Europe, we find a root called ῤᾶ or ῤῆον, mentioned by Dioscorides as brought from beyond the Bosphorus. The same drug is alluded to in the fourth century by Ammianus Marcellinus,[1805] who states that it takes its name from the river Rha (the modern Volga), on whose banks it grows. Pliny describes a root termed Rhacoma, which when pounded yielded a colour like that of wine but inclining to saffron, and was brought from beyond Pontus.

The drug thus described is usually regarded as rhubarb, or at least as the root of some species of Rheum, but whether produced in the regions of the Euxine (Pontus), or merely received thence from remoter countries, is a question that cannot be solved.

It is however certain that the name Radix pontica or Rha ponticum, used by Scribonius Largus[1806] and Celsus,[1807] was applied in allusion to the region whence the drug was received. Lassen has shown that trading caravans from Shensi in Northern China arrived at Bokhara as early as the year 114 b.c. Goods thus transported might reach Europe either by way of the Black Sea, or by conveyance down the Indus to the ancient port of Barbarike. Vincent suggests[1808] that the rha imported by the first route would naturally be termed rha-ponticum, while that brought by the second might be called rha-barbarum.

We are not prepared to accept this plausible hypothesis. It receives no support from the author of the Periplus of the Erythrean Sea (circa a.d. 64), whose list of the exports of Barbarike[1809] does not include rhubarb; nor is rhubarb named among the articles on which duty was levied at the Roman custom-house of Alexandria (a.d. 176-180).[1810]

The terms Rheum barbarum vel barbaricum or Reu barbarum occur in the writings of Alexander Trallianus[1811] about the middle of the 6th century, and in those of Benedictus Crispus,[1812] archbishop of Milan, and Isidore[1813] of Seville, who both flourished in the 7th century. Among the Arabian writers on medicine, the younger Mesue, in the early part of the 11th century, mentions the rhubarb of China as superior to the Barbaric or Turkish.[1814] Constantinus Africanus[1815] about the same period speaks of Indian and Pontic Rheum, the former of which he declares to be preferable. In 1154 the celebrated Arabian geographer Edrisi[1816] mentions rhubarb as a product of China, growing in the mountains of Buthink—probably the environs of north-eastern Tibet near Lake Tengri Nor (or Bathang in Western Szechuen?).

Rhubarb in the 12th century was probably imported from India, as we may infer from the tariff of duties levied at the port of Acon in Syria, in which document[1817] it is enumerated along with many Indian drugs. A similar list of a.d. 1271, relating to Barcelona, mentions Ruibarbo.[1818] In a statute of the city of Pisa called the Breve Fundacariorum, dating 1305, rhubarb (ribarbari) is classified with commodities of the Levant and India.[1819]

The first and almost the only European who has visited the rhubarb-yielding countries of China is the famous Venetian traveller, Marco Polo,[1820] who speaking of the province of Tangut says—“ ... et par toutes les montagnes de ces provinces se treuve le reobarbe en grant habondance. Et illec l’achatent les marchans et le portent par le monde.”

A sketch of the history of rhubarb would be incomplete without some reference to the various routes by which the drug has been conveyed to Europe from the western provinces of the Chinese Empire, and which have given rise to the familiar designations of Russian, Turkey and China Rhubarb.[1821]

The first route is that over the barren steppes of Central Asia by Yarkand, Kashgar, Turkestan, and the Caspian to Russia; the second by the Indus or the Persian Gulf to the Red Sea and Alexandria, or by Persia to Syria and Asia Minor; and the third by way of Canton, the only port of the Chinese Empire which, previous to the year 1842, held direct communication with Europe.

In 1653 China first permitted Russia to trade on her actual frontiers. The traffic in Chinese goods was thereupon diverted from the line of the Caspian and Black Sea further north, taking its way from Tangut across the steppes of the high Gobi, and through Siberia by Tobolsk to Moscow. Thus it is mentioned in 1719 that Urga on the north edge of the Gobi desert was the principal depôt for rhubarb. From the earliest times, Bucharian merchants appear to have been agents on this traffic, the producers of the drug never concerning themselves about its export.

Consequent on the rectification of frontier in 1728, a line of custom-houses was established by treaty between Russia and China, whereby the commerce, previously unrestricted, was limited to the government caravans which passed the frontier only at Kiachta and at Zuruchaitu, south of Nerchinsk. The latter place always remained unimportant, while Kiachta and the opposite Chinese town of Maimatchin became the staple depôts of rhubarb.

The root was subjected to special control as early as 1687-1697 by the Russian Government, who finally monopolized the trade about 1704. Caravans fitted out by the Crown alone brought the drug to Moscow, until 1762, when the caravan-trade was for a while thrown open. It was not until this period that the export of rhubarb became considerable, although the stringent regulations, established in 1736, were still maintained. The surveillance of rhubarb was exercised at Kiachta in a special court or office called the Brake,[1822] under instructions from the Russian Minister of War, by an apothecary appointed for six years, the object being to remove from the rhubarb brought for inspection all inferior or spurious pieces, and to improve the selected drug by trimming, paring and boring. It was then carefully dried, and packed in chests, which were sown up in linen, and rendered impervious to wet by being pitched and then covered with hide. The drug was dispatched, but only in quantities of 1000 puds (40,000 lb.), once a year by way of Lake Baikal and Irkutsk to Moscow, whence it was transmitted to St. Petersburg, to be there delivered to the Crown apothecaries and in part to be sold to druggists.

We are indebted for these accounts chiefly to Calau,[1823] an apothecary appointed to supervise the examination of rhubarb, and who resided a long time at Kiachta. An exact account of the remarkable policy of the Russian Government in relation to that drug was also given by Von Schröders[1824] in 1864.

So long as China kept all her ports closed to foreign commerce except Canton in the extreme south, a large supply of fine rhubarb found its way to Europe by way of Russia. But the unpleasant accompaniments of the Russian supervision, which was exercised with unsparing severity,[1825] and the extreme tediousness of the land-transport, made the Chinese very ready to accept an easier outlet for their goods. Accordingly we find that the opening of a number of ports in the north of China exerted a very depressing influence on the trade of Kiachta, which was augmented by the rebellion that raged in the interior of China for some years from 1852.

On these accounts Russia in 1855 removed certain restrictions on the trade, though without abandoning the Rhubarb Office. She withdrew in 1860 the custom-house to Irkutsk, and declared Kiachta a free port, while by the treaty with China of November 1860, she insisted on that country abandoning all restrictions on trade.

But the overland rhubarb trade had already been destroyed: the Chinese, tempted by the increased demand occasioned by the new trading-ports, became less careful in the collection and curing of the root, while the Russians insisted with the greatest strictness on the drug being of the accustomed quality. Hence it happened that from 1860 hardly any rhubarb was delivered at Kiachta, either for the government use or to private traders; and in 1863 the Rhubarb Office was abolished.

Thus the so-called Russian or Muscovitic or Crown Rhubarb, familiarly known in England as Turkey Rhubarb, a drug which for its uniformly good quality long enjoyed the highest reputation, has become a thing of the past, which can only now be found in museum collections. It began to appear in English commerce at the commencement of the last century. Alston,[1826] who lectured on botany and materia medica at Edinburgh in 1720, speaks of rhubarb as brought from Turkey and the East Indies,—“and of late, likewise from Muscovy.”

It has been shown (p. 494) that rhubarb was shipped from Syria in the 12th century. Vasco da Gama[1827] mentions it in 1497 among the exports of Alexandria. In fact, the drug was carried from the far east to Persia, whence it was brought by caravans to Aleppo, Tripoli, Alexandria, and even to Smyrna. From these Levant ports it reached Europe, and was distributed as Turkey Rhubarb; while that which was shipped direct from China, or by way of India, became known as China, Canton, or East India Rhubarb. The latter was already the more common sort in England as early as 1640.[1828]

As the rhubarb of the Levant disappeared from trade, that of Russia took not only its place but likewise its name, until the term “Turkey Rhubarb” came to be the accepted designation of the drug imported from Russia. This strange confusion of terms was not however prevalent on the Continent, but was chiefly limited to British trade.

The risk and expense of the enormous land-transport over almost the whole breadth of Asia, caused rhubarb in ancient times to be one of the very costly drugs. Thus at Alexandria in 1497, it was valued at twelve times the price of benzoin. In France in 1542,[1829] it was worth ten times as much as cinnamon, or more than four times the price of saffron. At Ulm in 1596,[1830] it was more costly than opium. A German price-list of the magistrate of Schweinfurt, of 1614, shows Radix Rha Barbari to be six times as dear as fine myrrh, and more than twice the price of opium. An official English list[1831] giving the price of drugs in 1657, quotes opium as 6s. per lb., scammony 12s., and rhubarb 16s.

Production and Commerce—The districts of the Chinese Empire which produce rhubarb extend over a vast area. They are comprised in the four northern provinces of China Proper, known as Chihli, Shansi, Shensi,[1832] and Honan; the immense north-western province of Kansuh, formerly partly included in Shensi, but now extending across the desert of Gobi and to the frontiers of Tibet; the province of Tsing-hai inhabited by Mongols, which includes the great salt lake of Koko-nor and the districts of Tangut, Sifan, and Turfan; and lastly the mountains of the western province of Szechuen. The plant is found on the pasturages of the high plateaux, growing particularly well on spots that have been enriched by encampments.

What little we know regarding the production of rhubarb and its preparation for the market, from Catholic missionaries,[1833] is of a rather meagre and unsatisfactory character. The root is dug up at the beginning of autumn when the vegetation of the plant is on the decline, and the operation is probably continued for a few months, or in some districts for the whole winter. It is cleaned, its cortical part sliced off, and the root cut into pieces for drying. This is performed either by the aid of fire-heat, or by simple exposure to sun and air, or the pieces are first partially dried on a hot stone, and then strung on a cord and suspended until the desiccation is complete.

According to F. von Richthofen[1834] the best rhubarb is collected exclusively from plants growing wild in the high alps of western Szechuen, especially in the Bayankara range, between the sources of the Hoang-ho and the rivers Ya-lung-Kiang and Min-Kiang. This variety is chiefly known under the name Shensi rhubarb, although the inhabitants of the province of Szechuen pretend the superiority of the drug of their own country. The important places for the commodity are Sining-fu in the province of Kansu, and Kwan-hien in Szechuen. In the plain of Tshing-tu-fu, according to Richthofen, rhubarb is cultivated in fields, but its product is stated to be much inferior to that of the true plant which is said not to succeed under culture.

Rhubarb is now purchased for the European market chiefly at Hankow on the upper Yangtsze, whither it is brought from the provinces of Shensi, Kansu, and Szechuen. From Hankow it is sent down to Shanghai, and there shipped for Europe. The exports from Hankow are stated in official documents[1835] to have amounted to the following numbers of peculs (one pecul = 133⅓ lb. = 60·479 kilogrammes):

1866 1867 1868 1869 1870 1871 1872

2985 3425 2866 3398 3370 3859 3167

In 1877 there were exported by way of Hankow 2096 peculs from Shensi and 3385 peculs from Szechuen.—From all the Chinese ports, 5124 peculs of rhubarb were shipped in 1874.

Much smaller quantities (554 peculs in 1872, 1055 peculs in 1874) are shipped from Tientsin; and there are occasional exportations from Canton, Amoy, Foochow, and Ningpo. The imports of rhubarb into the United Kingdom in 1870 amounted to 343,306 lb., the estimated value of which was £62,716.[1836]

We have no information about the rhubarb which is stated by Bellew[1837] to grow on the hills near Kayn or Ghayn in eastern Persia (about 32½° N. lat.).

Description—China Rhubarb as imported into Europe[1838] consists of portions of a massive root which display considerable diversity of form, arising from the various operations of paring, slicing and trimming, to which they have been subjected. Thus some pieces are cylindrical or rather barrel-shaped, others conical, while a large proportion are plano-convex, and others again are of no regular shape. These forms are not all found in the same package, the drug being usually sorted into round and flat rhubarb. In dimensions we find 3 to 4 inches the commonest length, though an occasional piece 6 inches long or more may be met with. The width may be stated at 2 to 3 inches. The outer surface of the root is somewhat shrivelled, often exhibiting portions of a dark bark that have not been pared away. Many pieces are pierced with a hole, in which may be found the remains of a cord used to suspend the root while drying. The drug is dusted over with a bright brownish-yellow powder, on removal of which the outer side of the root is seen to have a rusty-brown hue, or viewed with a lens to be marked by the medullary rays, which appear as an infinity of short broken lines of deep brown, traversing a white ground.

The character which most readily distinguishes the rhubarb of China is that well-developed pieces, broken transversely, display these dark lines arranged as an internal ring of star-like spots. Although this character is by no means obvious in every piece of Chinese rhubarb, it is of some utility from the fact that in European rhubarb, such spots are generally wholly wanting, or at most occur only sparingly and in an isolated manner.

In judging of rhubarb, great stress is laid upon the appearance of the root when broken, and the circumstance of the fractured surface presenting no symptoms of decay, discoloration, or sponginess.[1839] In good rhubarb, the interior is found to be compact, and beautifully veined with reddish-brown and white, sometimes not unmixed with iron-grey. The root when chewed tastes gritty, by reason of the crystals it contains of oxalate of calcium; but it is besides bitter, astringent and nauseous. The odour is peculiar, and except by the druggist, is mostly regarded as very disagreeable.

Microscopic Structure—The tissue of rhubarb is made up of a white parenchyme, brown medullary rays and a few irregularly scattered very large fibro-vascular bundles, which are devoid of ligneous cells.

On a transverse fracture of specimens, which are not too much peeled, a narrow dark cambial zone may be distinguished. In that part of the root, only the medullary rays display the usual radial arrangement, and in the interior of the root no regular structure is met with. There is no well-marked pith, but the central portion of the tissue shows a mixture of white parenchyme and brown medullary rays running in every direction. In full-grown roots, the central part is separated from the cambial zone by the band of stellate patches[1840] already mentioned.

As to the contents of the white cells, they are loaded either with starch or tufted crystals of oxalate of calcium, the amount of the latter being especially liable to variation. Scheele, after having discovered the oxalic acid, pointed out in 1784 that the crystals under notice consist of that acid in combination with lime; he was the first to point out the true composition of those crystals which are of so wide a distribution throughout the vegetable kingdom. The medullary rays contain the substances peculiar to rhubarb, but none of them occur in a crystalline state.

Chemical Composition—The active constituent of the root has long been supposed to reside in the yellowish-red contents of the medullary rays. Schrader as early as 1807 prepared a Rhubarb-Bitter, to which he attributed the medicinal powers of the drug. Since then several substances of the same kind have been separated by various methods, and described under different names: such are the Rhabarberstoff of Trommsdorff, the Rheumin of Hornemann, the Rhabarberin of Buchner and Herberger, the Rhubarb-Yellow or Rheïn, and the Rhabarbaric Acid of Brandes.

Schlossberger and Döpping in 1844 first recognized among the above-named substances a definite chemical body named Chrysophan or Chrysophanic Acid,

C₁₄H₅ CH₃ O₂,

(OH)₂

which had been found in 1843 by Rochleder and Heldt in the yellow lichen, Parmelia parietina. It partly forms the yellow contents of the medullary rays of rhubarb, and when isolated crystallizes in golden yellow needles or in plates. It dissolves in ether, alcohol, or benzol; though scarcely soluble in water, it is nevertheless extracted from the root to some extent by that solvent, probably by reason of some accompanying substance. Alkalis dissolve it, forming fine dark red solutions. Chrysophan, C₁₅H₁₀O₄, is a derivative of anthracene, C₁₄H₁₀, and closely allied to alizarin, C₁₄H₈O₄.

By precipitating alcoholic solutions of extract of rhubarb with ether, Schlossberger and Döpping obtained, together with chrysophan, resinous bodies which they named Aporetin, Phæoretin and Erythroretin.

De la Rue and Müller (1857) extracted from rhubarb, in addition to chrysophan, an allied substance, Emodin, which crystallizes in orange-coloured prisms, sometimes as much as two inches long. Its constitution was subsequently found to agree with the formula

C₁₄H₄ CH₃ O₂.

(OH)₃

Kubly (1867) has obtained from rhubarb the following constituents:—

1. Rheo-tannic Acid, C₂₆H₂₆O₁₄, a yellowish powder abundantly present in rhubarb, soluble in water or alcohol, not in ether. Its solutions produce blackish-green precipitates with persalts of iron, and greyish ones slowly turning blue, with protosalts of the same.

2. Rheumic Acid (Rheumsäure), C₂₀H₁₆O₉, obtained as a reddish-brown powder, by boiling rheo-tannic acid with a dilute mineral acid, a fermentable sugar being developed at the same time. Rheumic acid exhibits nearly the same reactions as rheo-tannic acid, but is very sparingly soluble in cold water. It partly pre-exists in rhubarb.

3. Neutral colourless substance, sparingly soluble in hot water, and separating from the latter in prismatic crystals of the formula C₁₀H₁₂O₄; no name has yet been given to it. A “white crystalline resin” (and a dark brown crystalline resin) has been isolated in 1878 by Dragendorff.

4. Phæoretin, C₁₆H₁₆O₇, agreeing with the substance thus named by Schlossberger and Döpping. It is a brown powder, soluble in alcohol or in acetic acid, but not in ether, chloroform or water.

5. Chrysophan, described above.

According to Dragendorff (1878) mucilaginous matters occur in the different varieties of rhubarb to the amount of from 11 to 17 per cent. He states them to consist of mucilage (properly so called), arabic acid, metarabic acid and pararabin, and moreover enumerates also pectose among the constituents of the drug.

Small quantities of albuminoid substances, malic acid, fat and sugar have also been met with in rhubarb. As to its mineral constituents, their amount is exceedingly variable. Two samples of good China Rhubarb dried at 100° C. and incinerated, yielded us respectively 12·9 and 13·87 per cent. of ash. Another sample, which we had particularly selected on account of its pale tint, afforded no less than 43·27 per cent. of ash. The ash consists of carbonates of calcium and potassium. English rhubarb from Banbury (portions of a large specimen) left after incineration 10·90 per cent. of ash.

From a practical point of view the chemical history of rhubarb is far from satisfactory, for we are still ignorant to what principle the drug owes its therapeutic value, or what are the pharmaceutical preparations in which the active matter may be most appropriately exhibited. Chrysophan is said to act as a purgative, but less powerfully than rhubarb itself.

Uses—Rhubarb is one of the commonest and most valuable purgatives; it is also taken as a stomachic and tonic.

Substitutes—These are found in the roots of the various species of Rheum cultivated in Europe. In most countries, the cultivation of rhubarb for medicinal use has at some time been attempted. Yet in but few instances has it been persistently carried on; and though the drug produced has often been of good appearance, it has failed to gain the confidence of medical men, and to acquire much importance in the drug-market. The European rhubarb most interesting from our point of view is

English Rhubarb—So early as 1535, Andrew Boorde, an English Carthusian monk and practitioner of medicine, obtained seeds of rhubarb, which he sent as “a grett tresure” to Sir Thomas Cromwell, Secretary of State to Henry VIII.; but as he says they “come owtt of barbary” we must be allowed to hold their genuineness as doubtful.[1841]

In the following century, namely about the year 1608, Prosper Alpinus of Padua cultivated as the True Rhubarb a plant which is now known as Rheum Rhaponticum L., a native of Southern Siberia and the regions of the Volga.[1842] From this stock, Sir Matthew Lister, physician to Charles I., procured seeds when in Italy, and gave them to Parkinson,[1843] who raised plants from them.

Collinson obtained rhubarb plants from seeds procured in Tartary, and sent to him in 1742 by Professor Siegesbeck of St. Petersburg.[1844]

About 1777 Hayward, an apothecary of Banbury in Oxfordshire, commenced the cultivation of rhubarb with plants of Rh. Rhaponticum, raised from seeds sent from Russia in 1762. The drug he produced was so good that the Society of Arts awarded him in 1789 a silver medal, and in 1794 a gold medal.[1845] The Society also awarded medals about the same time (1789-1793) to growers of rhubarb in Somersetshire, Yorkshire, and Middlesex, some of whom, it appears, cultivated Rh. palmatum. On the death of Hayward in 1811, his rhubarb plants came into the possession of Mr. P. Usher, by whose descendants, Mr. R. Usher and sons, they are still cultivated at Bodicott, a village near Banbury.

The authors of this book had the pleasure of inspecting the rhubarb fields of Messrs. Usher on Sept. 4, 1872, and of seeing the whole process of preparing the root for the market.[1846] The land under cultivation is about 17 acres, the soil being a rich friable loam. The roots are taken from the ground during the autumn up to the month of November. It is considered advantageous that they should be 6 or 7 years old, but they are seldom allowed to attain more than 3 or 4 years. The clumps of root as removed from the field to the yard, where the trimming takes place, are of huge size, weighing with the earth attached to them as much as 60 or 70 lb. They are partially cleaned, the smaller roots are cut off, and the large central portion is rapidly trimmed into a short, cylindrical mass the size of a child’s head. This latter subsequently undergoes a still further paring, and is finally sliced longitudinally; the other and less valuable roots are also pared, trimmed, and assorted according to size. The fresh roots are fleshy, easily cut, and of a beautiful deep yellow. All are dried in buildings constructed for the purpose, and heated by flues. The drying occupies several weeks. The root after drying has a shrivelled, unsightly appearance, which may be remedied by paring and filing. The finished drug has to be stored in a warm dry place.

When well prepared, Banbury rhubarb is of excellent appearance. The finest pieces, which are semi-cylindrical, are quite equal in size to the drug of China. The colour is as good, and the fractured surface exhibits pink markings not less distinct and brilliant. Even the smaller roots, which are dried as sticks, have internally a good colour, and afford a fine powder. But the odour is somewhat different from that of Chinese rhubarb; the taste is less bitter but more mucilaginous and astringent, and the root is of a more spongy, soft, and brittle texture. The structure is the same as that of the Chinese rhubarb, except that, as already stated, the star-like spots, if present, are isolated, and not arranged in a regular zone.

The drug commands but a low price, and is chiefly sold, it is said, for exportation in the state of powder. It is not easily purchased in London.

French and German Rhubarb—The cultivation of rhubarb was commenced in France in the latter half of the last century, and has been pursued with some enthusiasm in various localities. The species grown were Rheum palmatum L., Rh. undulatum L., Rh. compactum L., and Rh. Rhaponticum L. The first was thought by Guibourt[1847] to afford a root more nearly approaching than any other the rhubarb of China; but it is that which is cultivated the least readily, the central root being liable to premature decay. Both this plant and Rh. undulatum were formerly cultivated by order of the Russian Government on a large scale at Kolywan and Krasnojarsk in Southern Siberia, but the culture has, we believe, been long abandoned.[1848]

As to France, it appears from inquiries we have lately made (1873), that except in the neighbourhood of Avignon and in a few other scattered localities, the cultivation has now ceased.

Rheum Rhaponticum is the source of the rhubarb which is produced at Austerlitz and Auspitz in Moravia, and at Ilmitz, Kremnitz and Frauenkirchen in Hungary. Some rhubarb is also produced in Silesia from Rh. Emodi Wall. (Rh. australe Don.).

MYRISTICEÆ.

MYRISTICA.

Nuclei Myristicæ, Semen Myristicæ, Nux moschata; Nutmeg; F. Muscade, Noix de Muscade; G. Muskatnuss.

Botanical Origin—Myristica fragrans Houttuyn (M. moschata Thunb., M. officinalis Linn. f.), a handsome, bushy, evergreen tree,[1849] with dark shining leaves, growing in its native islands to a height of 40 to 50 feet. It is found wild in the very small volcanic group of Banda, from Damma to Amboina, in Ceram, Bouro, Jilolo (Halmahera), the western peninsula of New Guinea, and in many of the adjacent islands, but it is not indigenous to any of the islands westward of these, or to the Philippines (Crawfurd).

The nutmeg tree has been introduced into Bencoolen on the west coast of Sumatra, Malacca, Bengal, the islands of Singapore and Penang, as well as Brazil and the West Indies; but it is only in a very few localities that the cultivation has been attended with success.

In its native countries the tree comes into bearing in its ninth year, and is said to continue fruitful until 60 or even 80 years old, yielding annually as many as 2000 fruits. It is diœcious, and one male tree furnishes pollen sufficient for twenty female.

History—It has been generally believed that neither the nutmeg nor mace was known to the ancients. C. F. Ph. von Martius[1850] however maintains that mace was alluded to in the comedies of Plautus,[1851] written about two centuries before the Christian era.

The words Macer, Macar, Machir or Macir, occurring in the writings of Scribonius Largus, Dioscorides, Galen, and Pliny are thought by Martius to refer in each instance to mace. But that the substance designated by these names was not mace, but the bark of a tree growing in Malabar, was pointed out by Acosta nearly three centuries ago, and by many subsequent writers, and, as we think, with perfect correctness.[1852]

Nutmegs and mace were imported from India at an early date by the Arabians, and thus passed into western countries. Aëtius, who was resident at the court of Constantinople about the year 540, appears to have been acquainted with the nutmeg, if that at least is intended by the term Nuces Indicæ, prescribed together with cloves, spikenard, costus, calamus aromaticus and snadal-wood, as an ingredient of the Suffumigium moschatum.[1853]

Masudi,[1854] who appears to have visited India in a.d. 916-920, pointed out that the nutmeg, like cloves, areca nut and snadal-wood, was a product of the eastern islands of the Indian Archipelago. The Arabian geographer Edrisi, who wrote in the middle of the 12th century, mentions both nutmegs and mace as articles of import into Aden;[1855] and again “Nois mouscades” are among the spices on which duty was levied at Acre in Palestine, circa a.d. 1180.[1856] About a century later, another Arabian author, Kazwini,[1857] expressly named the Moluccas as the native country of the spices under notice.

The Sanskrit name of the nutmeg tree most commonly in use, also with Susruta, is Jātī (Dr. Rice).

One of the earliest references to the use of nutmegs in Europe occurs in a poem written about 1195, by Petrus D’Ebulo,[1858] describing the entry into Rome of the Emperor Henry VI., prior to his coronation in April 1191. On this occasion the streets were fumigated with aromatics, which are enumerated in the following line:—

“Balsama, thus, aloë, myristica, cynnama, nardus.”

By the end of the 12th century, both nutmegs and mace were found in Northern Europe,—even in Denmark, as may be inferred from the allusion to them in the writings of Harpestreng.[1859] In England, mace, though well known, was a very costly spice, its value between a.d. 1284 and 1377 being about 4s. 7d. per lb., while the average price of a sheep during the same period was but 1s. 5d., and of a cow 9s. 5d.[1860] It was also dear in France, for in the Compte de l’exécution of the will of Jeanne d’Evreux, queen of France, in 1372, six ounces of mace are appraised per ounce at 3 sols 8 deniers, equal to about 8s. 3d. of our present money.[1861]

The use of these spices was diffused throughout Europe long before the Portuguese in 1512 had discovered the mother plant in the isles of Banda. The Portuguese held the trade of the Spice Islands for about a century, when it was wrested from them by the Dutch, who pursued the same policy of exclusiveness that they had followed in the case of cloves and cinnamon. In order to secure their monopoly, they endeavoured to limit the trees to Banda and Amboyna, and to exterminate them elsewhere, which in fact they did at Ceram and the small neighbouring islands of Kelang and Nila. So completely was the spice trade in their hands, that the crops of sixteen years were said to be at one time in their warehouses, those of recent years being never thrown on the market. Thus the crop of 1744 was being sold in 1760, in which year an immense quantity of nutmegs and cloves was burned at Amsterdam lest the price should fall too low.[1862]

During the occupation of the Spice Islands by the English from 1796 to 1802, the culture of the nutmeg was introduced into Bencoolen and Penang,[1863] and many years afterwards into Singapore. Extensive plantations of nutmeg-trees were formed in the two islands last named, and by a laborious and costly system of cultivation were for many years highly productive.[1864] In 1860 the trees were visited by a destructive blight, which the cultivators were powerless to arrest, and which ultimately led to the ruin of the plantations, so that in 1867 there was no such thing as nutmeg cultivation either in Penang or Singapore.[1865]

Though so long valued in Europe and Asia, neither nutmegs nor mace seem to have been employed in former times as a condiment in the islands where they are indigenous.[1866]

Collection and Preparation—Almost the whole surface of the Banda Isles, observes Mr. Wallace,[1867] is planted with nutmeg-trees, which thrive under the shade of the lofty Canarium commune. The light volcanic soil, the shade, and the excessive moisture of these islands, where it rains more or less every month in the year, seem exactly to suit the nutmeg tree, which requires no manure and scarcely any attention.

In Bencoolen[1868] the trees bear all the year round, but the chief harvest takes place in the later months of the year, and a smaller one in April, May and June. The fruit as it splits is gathered by means of a hook attached to a long stick, the pericarp removed, and the mace carefully stripped off. The nuts are then taken to the drying house (a brick building), placed on frames, and exposed to the gentle heat of a smouldering fire, with arrangements for a proper circulation of air. This drying operation lasts for two months, during which time the nutmegs are turned every second or third day. At the end of this period, the kernels are found to rattle in the shell, an indication that the drying is complete. The shells are then broken with a wooden mallet, the nutmegs picked out and sorted, and finally rubbed over with dry sifted lime. In Banda the smaller and less sightly nutmegs are reserved for the preparation of the expressed oil.

The old commercial policy of the Dutch originated the singular practice of breaking the shell, and immersing the kernel of the artificially dried seed in milk of lime,—sometimes for a period of three months. This was done with a view to render impossible the germination of any nutmegs sent into the market. The folly of such a procedure was demonstrated by Teijsmann, who proved that mere exposure to the sun for a week is sufficient to destroy the vitality of the seed. By immersion in milk of lime many nutmegs are spoiled and the necessity is incurred of a second drying. Lumsdaine has also shown that even the dry liming process is, to say the least, entirely needless. Nutmegs are well preserved in their natural shell, in which state the Chinese have the good sense to prefer them.

The process of liming nutmegs is however still largely followed; and the prejudice in favour of the spice thus prepared is so strong in certain countries, that nutmegs not limed abroad have sometimes to be limed in London to fit them for exportation. Penang nutmegs are always imported in the natural state,—that is, un-limed.

Description—The fruit of Myristica fragrans is a pendulous, globose drupe, about 2 inches in diameter, and not unlike a small round pear. It is marked by a furrow which passes round it, and by which at maturity its thick fleshy pericarp splits into two pieces, exhibiting in its interior a single seed, enveloped in a fleshy foliaceous mantle or arillus, of fine crimson hue, which is mace. The dark brown, shining, ovate seed is marked with impressions corresponding to the lobes of the arillus; and on one side, which is of paler hue and slightly flattened, a line indicating the raphe may be observed.

The bony testa does not find its way into European commerce, the so-called nutmeg being merely the kernel or nucleus of the seed. Nutmegs exhibit nearly the form of their outer shell with a corresponding diminution in size. The London dealers esteem them in proportion to their size, the largest, which are about one inch long by ⁸/₁₀ of an inch broad, and four of which will weigh an ounce, fetching the highest price. If not dressed with lime, they are of a greyish brown, smooth yet coarsely furrowed and veined longitudinally, marked on the flatter side with a shallow groove. A transverse section shows that the inner seed-coat (endopleura) penetrates into the albumen in long narrow brown strips, reaching the centre of the seed, thereby imparting the peculiar marbled appearance familiar in a cut nutmeg.

At the base of the albumen and close to the hilum, is the embryo, formed of a short radicle with cup-shaped cotyledons, whose slit and curled edges penetrate into the albumen. The tissue of the seed can be cut with equal facility in any direction. It is extremely oily, and has a delicious aromatic fragrance, with a spicy rather acrid taste.

Microscopic Structure—The testa consists mainly of long, thin, radially arranged, rigid cells, which are closely interlaced and do not exhibit any distinct cavities. The endopleura which forms the adhering coat of the kernel and penetrates into it, consists of soft-walled, red-brown tissue, with small scattered bundles of vessels. In the outer layers the endopleura exhibits small collapsed cells; but the tissue which fills the folds that dip into the interior consists of much larger cells. The tissue of the albumen is formed of soft-walled parenchyme, which is densely filled with conspicuous starch-grains, and with fat, partly crystallized. Among the prismatic crystals of fat, large thick rhombic or six-sided tables may often be observed. With these are associated grains of albuminoid matter, partly crystallized.

Chemical Composition—After starch and albuminoid matter, the principal constituent of nutmeg is the fat, which makes up about a fourth of its weight, and is known in commerce by the incorrect name of Oil of Mace (see p. 507).

The volatile oil, to which the smell and taste of nutmegs are chiefly due, amounts to between 3 and 8 per cent.,[1869] and consists, according to Cloëz (1864), almost entirely of a hydrocarbon, C₁₀H₁₆, boiling at 165° C., which Gladstone (1872), who assigns it the same composition, calls Myristicene. The latter chemist found in the crude oil an oxygenated oil, Myristicol, of very difficult purification and possibly subject to change during the process of rectifying. It has a high boiling point (about 220° C.?) and the characteristic odour of nutmeg; unlike carvol with which it is isomeric, it does not form a crystalline compound with hydrosulphuric acid.

Oil of nutmegs, distilled in London by Messrs. Herrings and Co., examined in column 200 mm. long, we found to deviate the ray of polarized light, 15°·3 to the right; that of the Long Nutmeg (Myristica fatua Houtt.), furnished to us by the same firm, deviated 28°·7 to the right.

From the facts recorded by Gmelin,[1870] it would appear that oil of nutmeg sometimes deposits a stearoptene called Myristicin. We are not acquainted with such a deposit; yet we have been kindly furnished by Messrs. Herrings with a crystalline substance which they obtained during the latter part of the process of distilling both common and long nutmegs. It is a greyish greasy mass, which by repeated crystallizations from spirit of wine, we obtained in the form of brilliant, colourless scales, fusible at 54° C., and still possessing the odour of nutmeg. The crystals are readily soluble in benzol, bisulphide of carbon or chloroform, sparingly in petroleum ether; their solution in spirit of wine has a decidedly acid reaction, and is devoid of rotatory power. By boiling them with alcohol, sp. gr. 0·843, and anhydrous carbonate of sodium, we obtained a solution which, after removal of the alcohol, left a residuum perfectly soluble in boiling water, forming a jelly on cooling. By adding hydrochloric acid to the warm aqueous solution, the original crystallizable substance again made its appearance, yet almost devoid of odour. It is in fact nothing else than Myristic Acid (see page 508).[1871]

Production and Commerce—The nutmegs and mace now brought into the market are to a large extent the produce of the Banda Islands,[1872] of which however only three, namely Lontar or the Great Banda, Pulo Ai, and Pulo Nera, have what are termed Nutmeg Parks. According to official statements of the Dutch, the first-named island possessed in 1864 about 266,000 fruit-bearing trees; Ternate on the western coast of Jilolo, 46,000; Menado in the island of Celebes, 35,000; and Amboyna, only 31,000. The nutmegs of the Banda Islands are shipped to Batavia. The quantity exported from Java in 1871 (all, we believe, from Batavia, and therefore the produce of the Banda Islands) is stated as 8107 peculs (1,080,933 lb.), of which 2300 peculs (306,666 lb.) were shipped to the United States, and a rather large quantity to Singapore.[1873] The last named port also shipped in the same year a very large quantity (310,576 lb.) of nutmegs to North America,[1874] and in 1877 the total export of nutmegs and mace from Singapore was 5323 peculs (709,733 lb.).

Nutmegs were exported from Padang in Sumatra in the year 1871, to the extent of 2766 peculs (368,800 lb.), chiefly to America and Singapore. The quantity annually imported into the United Kingdom ranges from 500,000 to 800,000 lb.

Uses—Nutmeg is a grateful aromatic stimulant, chiefly employed for flavouring other medicines. It is also in constant use as a condiment, though less appreciated than formerly.

Oleum Myristicæ expressum.

Oleum Macidis, Balsamum vel Oleum Nucistæ; Expressed Oil of Nutmegs, Nutmeg Butter, Oil of Mace; F. Beurre de Muscade; G. Muskatbutter, Muskatnussöl.

This article reaches England chiefly from Singapore, in oblong, rectangular blocks, about 10 inches long by 2½ inches square, enveloped in a wrapper of palm leaves. It is a solid unctuous substance of an orange-brown colour, varying in intensity of shade, and presenting a mottled aspect. It has a very agreeable odour and a fatty aromatic taste.

In operating on 2 lb. of nutmegs, first powdered and heated in a water-bath and pressed while still hot, we obtained 9 ounces of solid oil, equivalent to 28 per cent. This oil, which in colour, odour and consistence does not differ from that which is imported, melts at about 45° C.; and dissolves perfectly in two parts of warm ether or in four of warm alcohol sp. gr. ·800.

Nutmeg butter contains the volatile oil already described, to the extent of about six per cent., besides several fatty bodies. One of the latter, termed Myristin C₃H₅(O·C₁₄H₂₇O)₃, may be obtained by means of benzol, or by dissolving in ether that part of the butter of nutmeg which is insoluble in cold spirit of wine. The crystals of myristin melt at 31° C. By saponification they furnish glycerin, and Myristic Acid, C₁₄H₂₈O₂, the latter fusing at 53°·8 C. Playfair in 1841 was the first to isolate (in Liebig’s laboratory at Giessen) myristic acid. Myristin also occurs in spermaceti, coco-nuts, as well as, according to Mulder, in small quantity, in the fixed oils of linseed and poppy seed. Nutmegs according to Comar (1859) yield 10 to 12 per cent. of myristin.

That part of nutmeg butter, which is more readily soluble in spirit of wine or benzol, contains another fat, which however has not yet been investigated. It is accompanied by a reddish colouring matter.

MACIS.

Mace; F. Macis; G. Macis, Muskatblüthe.

Botanical Origin—Myristica fragrans Houttuyn (see p. 502). The seed which, deprived of its hard outer shell or testa, is known as the nutmeg, is enclosed when fresh in a fleshy net-like envelope, somewhat resembling the husk of a filbert. This organ, which is united, though not very closely, at the base of the stony shell both with the hilum and the contiguous portion of the raphe, of which parts it is an expansion, is termed arillus,[1875] and when separated and dried constitutes the mace of the shops. In the fresh state it is fleshy, and of a beautiful crimson; it envelopes the seed completely only at the base, afterwards dividing itself into broad flat lobes; which branch into narrower strips overlapping one another towards the summit.

History—Included in that of the nutmeg (see preceding article).

Description—The mace, separated from the seed by hand, is dried in the sun, thereby losing its brilliant red hue and acquiring an orange-brown colour. It has a dull fatty lustre, exudes oil when pressed with the nail, and is horny, brittle, and translucent. Steeped in water it swells rather considerably. The entire arillus, compressed and crumpled by packing, is about 1¾ inches long with a general thickness of about ¹/₂₀ of an inch or even at ⅒ the base. Mace has an agreeable aromatic smell nearly resembling that of nutmeg, and a pungent, spicy, rather acrid taste.

Microscopic Structure—The uniform, small-celled, angular parenchyme is interrupted by numerous brown oil-cells of larger size. The inner part of the tissue contains also thin brown vascular bundles. The cells of the epidermis on either side are colourless, thick-walled, longitudinally extended, and covered with a peculiar cuticle of broad, flat, riband-like cells, which cannot however be removed as a continuous film. The parenchyme is loaded with small granules, to which a red colour is imparted by Millon’s test (solution of mercurous nitrate) and an orange hue by iodine. The granules consequently consist of albuminous matter, and starch is altogether wanting.

Chemical Composition—The nature of the chemical constituents of mace may be inferred from the following experiments performed by one of us:—17 grammes of finely powdered mace were entirely exhausted by boiling ether, and the latter allowed to evaporate. It left behind 5·57 grm., which after drying at 100° C. were diminished to 4·17. The difference, 1·40 grammes, answers to the amount of essential oil, of which consequently 8·2 per cent. had been present.

The residue, amounting to 24·5 per cent., was a thickish aromatic balsam, in which we have not been able to ascertain the presence of fat; it consisted of resin and semi-resinified essential oil. Alcohol further removed 1·4 per cent. of an uncrystallizable sugar, which reduced cupric oxide.

The drug having been thus treated with ether and with alcohol, yielded almost nothing to cold water, but by means of boiling water 1·8 per cent. of a mucilage was obtained, which turned blue by addition of iodine, or reddish violet if previously dried. This substance is not soluble in an ammoniacal solution of cupric oxide; it appears rather to be an intermediate body between mucilage and starch.[1876] The composition of mace is therefore very different from that of nutmeg.

As to the volatile oil, of which several observers have obtained from 7 to 9 per cent.,[1877] it is a fragrant colourless liquid which we found, when examined in a column 200 mm. long, deviated the ray 18°·8 to the right. Its greater portion consists according to Schacht (1862) of Macene, C₁₀H₁₆, boiling at 160° C., and distinguished from oil of turpentine by not forming a crystalline hydrate when mixed with alcohol and nitric acid. Koller (1865) states that macene is identical with the hydrocarbon of oil of nutmeg (myristicene), yet the latter is said by Cloëz to yield no solid compound when treated with hydrochloric gas. Macene on the other hand furnishes crystals of C₁₀H₁₆·HCl. Crude oil of mace contains, like that of nutmeg, an oxygenated oil, the properties of which have not yet been investigated.

Commerce—Mace, mostly the produce as it would appear of the Banda Islands, was shipped from Java in 1871 to the extent of 2101 peculs (282,133 lb.); and from Padang in Sumatra (excluding shipments to Java) to the amount of 457 peculs (60,933 lb.).[1878] The spice is exported principally to Holland, Singapore, and the United States; Great Britain receives about 60,000 to 80,000 lb. annually.

Uses—Mace is but rarely employed in medicine. It is chiefly consumed as a condiment.

LAURACEÆ.

CAMPHORA.

Camphor,[1879] Common Camphor, Laurel Camphor; F. Camphre; G. Campher.

Botanical Origin—Cinnamomum Camphora Fr. Nees et Ebermaier (Laurus Camphora L., Camphora officinarum C. Bauh.), the Camphor tree or Camphor Laurel is widely diffused, being found throughout Central China and in the Japanese Islands. In China it abounds principally in the eastern and central provinces, as in Chekiang, Fokien and Kiangsi; but it is wanting, according to Garnier (1868), in Yünnan and Szechuen. It is plentiful, on the other hand, in the island of Formosa, where it covers the whole line of mountains from north to south, up to an elevation of 2000 feet above the level of the sea. It flourishes in tropical and subtropical countries, and forms a large and handsome tree in sheltered spots in Italy as far north as the Lago Maggiore. The leaves are small, shining, and glaucous beneath, and have long petioles; the stem affords excellent timber, much prized on account of its odour for making clothes’ chests and drawers of cabinets.

Dryobalanops aromatica, the camphor tree of Borneo and Sumatra, yields a peculiar camphor, which we shall describe further on.

History—The two kinds of Camphor afforded by the two trees just named have always been regarded by the Chinese as perfectly distinct substances, and in considering the history of camphor this fact must be borne in mind.

On perusing the accounts of Laurel Camphor given by Chinese writers,[1880] the remarkable fact becomes apparent, that although the tree was evidently well known in the 6th century, and probably even earlier, and is specially noticed on account of its valuable timber, no mention is made in connexion with it of any such substance as camphor.

Le-she-chin, the author of the celebrated herbal Pun-tsao-kang-muh, written in the middle of the 16th century, was well acquainted with the two sorts of camphor,—the one produced by the camphor laurel of his own country, the other imported from the Malay islands; and he narrates how the former was prepared by boiling the wood, and refined by repeated dry sublimations.

Marco Polo, towards the end of the 13th century, saw the forests of Fokien in South-eastern China, in which, says he, are many of the trees which give camphor.[1881] It would thus appear that Laurel Camphor was known as early as the time of Marco Polo, yet it is certain that the more ancient notices which we shall now quote have reference to the much valued Malay Camphor, which remains up to the present day one of the most precious substances of its class.

There is no evidence that camphor reached Europe during the classical period of Greece and Rome. The first mention of it known to us occurs in one of the most ancient monuments of the Arabic language, the poems of Imru-l-Kais,[1882] a prince of the Kindah dynasty, who lived in Hadramaut in the beginning of the 6th century. Nearly at the same period, Aëtius of Amida (the modern Diarbekir) used camphor medicinally, but from the manner in which he speaks of it, it was evidently a substance of some rarity.[1883]

In fact, for many centuries subsequent to this period, camphor was regarded as one of the most rare and precious of perfumes. Thus, it is mentioned in a.d. 636, with musk, ambergris, and snadal-wood, among the treasures of Chosroes II., of the Sassanian dynasty of kings of Persia, in the palace at Madain on the Tigris, north of Babylon.[1884]

Among the immense mass of valuables dispersed at Cairo on the downfall of the Fatimite Khalif Mostanser in the 11th century, the Arabian historians[1885] enumerate with astonishment, besides vast quantities of musk, aloes wood, snadal-wood, amber, large stores of Camphor of Kaisur, and hundreds of figures of melons in camphor, adorned with gold and jewels, which were contained in precious vessels of gold and porcelain. One grain (crystal?) of camphor is mentioned as weighing 5 mithkals, one melon of the weight of 70 mithkals, was contained in a golden box weighing no less than 3,000 mithkals (1 mithkal = 71·49 gr. Troy = 4·63 grammes). It is also on record that about a.d. 642, Indian princes sent camphor as tribute or a gift to the Chinese Emperors;[1886]—further, that in the Teenpaou period (a.d. 742-755), the Cochinchinese brought to the Chinese court a tribute of Barus camphor, said by the envoy to be found in the trunks of old trees, the like of which for fragrance was never seen again.[1887] Masudi,[1888] four centuries later, mentions a similar present from an Indian to a Chinese potentate, when 1,000 menn[1889] of aloes-wood were accompanied by 10 menn of camphor, the choice quality of the latter being indicated by the remark that it was in pieces as large or larger than a pistachio-nut.

Again, between a.d. 1342 and 1352, an embassy left Pekin bearing a letter from the Great Khan to Pope Benedict XII., accompanied by presents of silk, precious stones, camphor, musk, and spices.[1890]

Ibn Batuta, the celebrated traveller, relates that after having visited the King of Sumatra, he was presented on leaving (a.d. 1347) with aloes-wood, camphor, cloves, and sandal-wood, besides provisions.

Ishâk ibn Amrân, an Arabian physician living towards the end of the 9th century, and Ibn Khurdádbah, a geographer of the same period, were among the first to point out that camphor is an export of the Malayan Archipelago; and their statements are repeated by the Arabian writers of the middle ages, who all assert that the best camphor is produced in Fansúr. This place, also called Kansúr or Kaisúr, was visited in the 13th century by Marco Polo, who speaks of its camphor as selling for its weight in gold; Yule[1891] believes it to be the same spot as Barus, a town on the western coast of Sumatra, still giving a name to the camphor produced in that island.

From all these facts and many others that might be adduced,[1892] it undoubtedly follows that the camphor first in use was that found native in the trunk of the Sumatran Dryobalanops aromatica, and not that of the Camphor Laurel. At what period and at whose instigation the Chinese began to manufacture camphor from the latter tree is not known.

Camphor was known in Europe as a medicine as early as the 12th century, as is evident from the mention of it by the abbess Hildegard[1893] (who calls it ganphora), Otho of Cremona,[1894] and the Danish canon Harpestreng (ob. a.d. 1244).

Garcia de Orta states (1563) that it is the camphor of China which alone is exported to Europe, that of Borneo and Sumatra being a hundred times more costly, and all consumed by eastern nations. They partly devoted the latter to ritual purposes, as for instance embalming, partly to “eating,” i.e. for the preparation of the betel-leaves for chewing. Neuhof[1895] states that the other ingredients used in China for that purpose are: Areca nuts (see article Semen Arecæ) and lime or Lycium (see page 35), Caphur de Burneo, aloë (i.e. Aloë-wood, see Aloë), and musk. Kämpfer,[1896] who resided in Japan in 1690-92, and who figured the Japanese camphor tree under the name Laurus camphorifera, expressly declares the latter to be entirely different from the camphor tree of the Indian Archipelago. He further states that the camphor of Borneo was among the more profitable commodities imported into Japan by the Dutch, whose homeward cargoes included Japanese camphor to the extent of 6,000 to 12,000 lb. annually.[1897] This camphor was refined in Holland by a process long kept secret, and was then introduced into the market. In Pomet’s time (1694 and earlier), crude camphor was common in France, but it had to be sent to Holland for purification.

It is doubtful whether at that period, or even much later, any camphor was obtained from Formosa. Du Halde[1898] makes no allusion to it as a production of that island; nor does he mention it among the commodities of Emouy (Amoy), which was the Chinese port then in most active communication with Formosa.

Production—The camphor of European commerce is produced in the island of Formosa and in Japan. We have no evidence that any is manufactured at the present day in China, although very large trees, often from 8 to 9 feet in diameter, are common, for instance in Kiangsi, and camphor wood is an important timber of the Hankow market.

In Formosa, the camphor-producing districts lie in the narrow belt of debateable ground, which separates the border Chinese settlements from the territory still occupied by the aboriginal tribes. The camphor is prepared from the wood, which is cut into small chips from the trees, by means of a gouge with a long handle. In this process there is great waste, many trees being cut and then left with a large portion of valuable timber to perish. The next operation is to expose the wood to the vapour of boiling water, and to collect the camphor which volatilizes with the steam. For this purpose, stills are constructed thus:—a long wooden trough, frequently a hollowed trunk, is fixed over a furnace and protected by a coating of clay. Water is poured into it, and a board perforated with numerous small holes is luted over it. Above these holes the chips are placed and covered with earthen pots. A fire having been lighted in the furnace, the water becomes heated, and the steam passing through the chips, carries with it the camphor, which condenses in minute white crystals in the upper part of the pots. From these it is scraped out every few days, and is then very pure and clean. Four stills, each having ten pots placed in a row over one trough, are generally arranged under one shed. These stills are moved from time to time, according as the gradual exhaustion of timber in the locality renders such transfer desirable. A considerable quantity of camphor is however manufactured in the towns, the chips being conveyed thither from the country. A model of a much better still, which was contributed from Formosa to the Paris Exhibition in 1878, is perhaps referring to a town manufacture.

Camphor is brought from the interior to Tamsui, the chief port of Formosa, the baskets holding about half a pecul each (1 pecul = 133⅓ lbs.), lined and covered with large leaves. Upon arrival, it is stored in vats holding from 50 to 60 peculs each, or it is packed at once in the tubs, or lead-lined boxes, in which it is exported. From the vats or tubs there drains out a yellowish essential oil known as Camphor Oil, which is used by the Chinese in rheumatism.[1899] In 1877 hydraulic pressure has been established for the separation of the oil and moisture; the raw camphor loses about 20 per cent. of these admixtures.

Kämpfer in his account[1900] of the manufacture of camphor in the Japanese province of Satzuma and in the islands of Gotho, describes the boiling of the chips in an iron pot covered with an earthen head containing straw in which the camphor collects. In the province of Tosa, island of Sikok, there is now a still in use, which is quite conveniently combined with a cooling apparatus consisting of a wooden trough, over which cold water is flowing.[1901]

Purification—Camphor as it is exported from Japan and Formosa requires to be purified by sublimation. The crude drug consists of small crystalline grains, which cohere into irregular friable masses, of a greyish-white or pinkish hue. Dissolved in spirit of wine, it leaves from 2 to 10 per cent. of impurities consisting of gypsum, common salt, sulphur, or vegetable fragments.

In Europe, crude camphor is sublimed from a little charcoal or sand, iron filings or quicklime, and sent into the market as Refined Camphor in the form of large bowls or concave cakes, about 10 inches in diameter, 3 inches in thickness, and weighing from 9 to 12 lb.[1902] Each bowl has a large round hole at the bottom, corresponding to the aperture of the vessel in which the sublimation has been conducted. This operation is performed in peculiar glass flasks termed bomboloes, in the upper half of which the pure camphor concretes. These flasks having been charged and placed in a sand-bath, are rapidly heated to about 120°-190° C. in order to remove the water. Afterwards the temperature is slowly increased to about 204° C., and maintained during 24 hours. The flasks are finally broken.

As camphor is a neutral substance, the addition of lime probably serves merely to retain traces of resin or empyreumatic oil. Iron would keep back sulphur were any present.

In the United States the refiners use iron vessels; their product is in flat disks, about 16 inches in diameter by one inch in thickness.

The refining of camphor is carried on to a large extent in England, Holland, Hamburg, Paris, Bohemia (Aussig), in New York and Philadelphia. It is a process requiring great care on account of the inflammability of the product. The temperature must also be nicely regulated, so that the sublimate may be deposited not merely in loose crystals, but in compact cakes. In India where the consumption of camphor is very large, the natives effect the sublimation in a copper vessel, the charge of which is 1½ maunds (42 lb.): fire is applied to the lower part, the upper being kept cool.[1903]

Description—Purified Camphor forms a colourless crystalline, translucent mass, traversed by numerous fissures, so that notwithstanding a certain toughness, a mass can readily be broken by repeated blows. By spontaneous and extremely slow evaporation at ordinary temperatures, camphor sublimes in lustrous hexagonal plates or prisms, having but little hardness. If triturated in a mortar, camphor adheres to the pestle, so that it cannot be powdered per se. But if moistened with spirit of wine, ether, chloroform, methylic alcohol, glycerin, or an essential or fatty oil, pulverization is effected without difficulty. By keeping a short time, the powder acquires a crystalline form. With an equal weight of sugar, camphor may also be easily powdered.

Camphor melts at 175° C., boils at 204°, and volatilizes somewhat rapidly even at ordinary temperatures. To this latter property, combined with slight solubility, must be attributed the curious rotatory motion which small lumps of camphor (as well as barium butyrate, stannic bromide, chloral hydrate, and a few other substances) exhibit when thrown on to water.

The solubility of camphor in water is very small, 1300 parts dissolving about one; but even this small quantity is partially separated on addition of some alkaline or earthy salt, as sulphate of magnesium. Alcohols, ethers, chloroform, carbon bisulphide, volatile and fixed oils and liquid hydrocarbons, dissolve camphor abundantly.

The sp. gr. of camphor at 0° C. and up to 6° is the same as that of water; yet at a somewhat higher temperature, camphor expands more quickly, so that at 10° to 12° C. its sp. gr. is only 0·992.

In concentrated solution or in a state of fusion, camphor turns the plane of polarization strongly to the right. Officinal solution of camphor (Spiritus Camphoræ) is too weak, and does not deviate the ray of light to a considerable amount.[1904] Crystals of camphor are devoid of rotatory power.

The taste and odour of camphor are sui generis, or at least are common only to a group of nearly allied substances. Camphor is not altered by exposure to air or light. It burns easily, affording a brilliant smoky flame.

Chemical Composition—Camphor, C₁₀H₁₆O, by treatment with various reagents, yields a number of interesting products: thus when repeatedly distilled with chloride of zinc or anhydrous phosphoric acid, it is converted into Cymene or Cymol, C₁₀H₁₄, a body contained in many essential oils, or obtainable therefrom.

Camphor, and also camphor oil, when subjected to powerful oxidizing agents, absorbs oxygen, passing gradually into crystallized Camphoric Acid, C₁₀H₁₆O₄ or C₈H₁₄(COOH)₂, water and carbonic acid being at the same time eliminated. Many essential oils, resins and gum-resins likewise yield these acids when similarly treated.

By means of less energetic oxidizers, camphor may be converted into Oxy-Camphor, C₁₀H₁₆O₂, still retaining its original odour and taste (Wheeler, 1868).

Commerce—Two kinds of crude camphor are known in the English market, namely:

1. Formosa or China Camphor, imported in chests lined with lead or tinned iron, and weighing about 1 cwt. each; it is of a light brown, small in grain, and always wet, as the merchants cause water to be poured into the cases before shipment, with a view, it is pretended, of lessening the loss by evaporation. The exports of this camphor from Tamsui in Formosa[1905] were in peculs (one pecul = 13·33 lb. avdp. = 60·479 kilogrammes) as follows:

1870 1871 1872 1875 1876 1877

14,481 9691 10,281 7139 8794 13,178

The shipments of camphor from Takow, the other open port of Formosa, are of insignificant amount. Planks of camphor wood are now exported in some quantity from Tamsui.

2. Japan Camphor is lighter in colour and occasionally of a pinkish tint; it is also in larger grains. It arrives in double tubs (one within the other) without metal lining, and hence is drier than the previous sort; the tubs hold about 1 cwt. It fetches a somewhat higher price than the Formosa camphor.

Hiogo and Osaka exported in 1871, 7089 peculs (945,200 lb.), and Nagasaki 745 peculs (99,333 lb.), the total value being 116,718 dollars.[1906] In 1877 the value of camphor exported from Japan was stated to be equal to 240,000 dollars. The imports of Unrefined Camphor into the United Kingdom amounted in 1870 to 12,368 cwt. (1,385,216 lb.); of Refined Camphor in the same year to 2361 cwt.[1907]

Camphor is largely consumed by the natives of India; the quantity of the crude drug imported into Bombay in the year 1872-73 was 3801 cwt.[1908]

Uses—Camphor has stimulant properties and is frequently used in medicine both internally and externally. It is largely consumed in India.

Other kinds of Camphor; Camphor Oils.

Camphor, as stated above at page 512, was the name originally applied to the product of Dryobalanops; it was then also given to that of Camphor Laurel, and in 1725 Caspar Neumann, of Berlin, first pointed out that many essential oils afford crystals (“stearoptenes” of later chemists), for which he proposed the general name of camphor. Many of them are agreeing with the formula C₁₀H₁₆O, and there are also numerous liquids of the same composition. It would appear, however, that no stearoptene of any other plant is absolutely identical with common camphor; Lallemand’s statement (see p. 479), that oil of spike affords the latter, requires further examination.

Many other liquid and solid constituents of essential oils, or substances afforded by treating them with alcoholic potash, answer to the formula C₁₀H₁₇(OH). Among them we may point out the two following: they are the only substances of the class of “camphors,” besides common camphor, which are of some practical importance.