Note 148 — PART IV CONTRIBUTIONS FROM THE JOURNAL: MISCELLANEOUS MATTER

Osborne and Mendel have shown (Jour. Biol. Chem., 1913, xv, 311) that mixtures of purified protein, lard, starch and protein-free milk have been singularly efficient for a time in promoting growth of young rats. In from sixty to 100 days or more, however, normal growth stops; the animals may remain at constant weight for a few days, or grow very slowly, and then suddenly decline and die unless a change is made in the diet. The substitution of butter-fat, egg yolk fat, or cod liver oil for a portion of the lard in the ration, in the experiments of these authorities, brought prompt recovery and continuation of normal growth.