2 Chronicles 21:16

Behold, with a great plague will the LORD smite thy people, and thy children, and thy wives, and all thy goods:

And thou shalt have great sickness by disease of thy bowels, until thy bowels fall out by reason of the sickness day by day.

And they came up into Judah, and brake into it, and carried away all the substance that was found in the king’s house, and his sons also, and his wives; so that there was never a son left him, save Jehoahaz, the youngest of his sons.

And after all this the LORD smote him in his bowels with an incurable disease.