INDEX
Reading edition
A
Acid, effect on keeping qualities of antiscorbutics, 66, 161
Acidosis, 244 theory, 24
Adrenals, 102 in guinea-pig scurvy, 122
Adult, scurvy in, history of, 1
Age incidence, 51
Aging, effect on antiscorbutics of, 67
Agglutinins, effect of scurvy on, 68
Alimentary tract, gross pathology, 89 microscopic pathology, 100
Alkalization, effect on milk of, 50 on orange juice of, 66, 154
Amboceptor, effect of scurvy on, 68
Anasarca, 86, 196
Animals, scurvy in, 114
Anorexia, 206
Antiscorbutics, and antiscorbutic foods, 143, 149, 157 history of use of, 9, 143
Antitoxin, effect of scurvy on, 68
Appendicitis, confused diagnosis, 183
Appetite, 206
Apple, antiscorbutic value of, 158
Armies, scurvy in, 3, 15
Army, use of canned tomatoes in ration of U. S., 231
B
Bacteria, fecal, in scurvy, 28 as etiological factor in scurvy, 134 in tissues, 133
Bacterial theory of scurvy, 30
Banana, antiscorbutic value of, 158
Beading of ribs, 197 in guinea-pig, 129, 137 pathology of, 94
Beans, germinated, 167, 231
Beef juice, 236
Beer, antiscorbutic value of, 20, 169
Beriberi, differential diagnosis, 221 relation to scurvy, 249
Berries, antiscorbutic value of, 156
Blindness, 182
Blood cells, changes in, 209–211
Blood cells, chemistry of, 244, 245 coagulability of, 211
Blood vessels, changes in, 68, 98, 209 in guinea-pigs, 133
Blood, vitamine content of, 76
Bones, gross pathology, 93 microscopic pathology, 105
Brain, pathology, 93
Breast fed, scurvy in, 35
C
Cabbage, antiscorbutic value of, 159 dehydrated, 165 effect of heat on, 159
Calcium, deposits of, 98, 102, 103 metabolism, 241–247
“Capillary resistance test,” 212, 257
Carbohydrates, 34, 59
“Cardiorespiratory syndrome,” 200
Cardiovascular system, 199
Carrots, antiscorbutic value of, 159, 160
Central nervous system, gross pathology, 93 microscopic pathology, 104
Cereals, antiscorbutic value of, 170 germinated, 167
Cerebrospinal fluid, 203
Chlorides, 242–247
Citric acid theory, 23
Climate, 55
Complement, effect of scurvy on, 69
Complexion, characteristic change in, 176, 184
Complications of scurvy, 182, 202, 205, 217
Constipation, 27, 118–122, 207
Cord, spinal, pathology, 93, 104
Creatinine, 244
Cure, 236
D
Death, causes of, 179, 227
Deficiency diseases, general discussion, 63, 248
Diagnosis, 176, 219
Diastase, blood content of, 244
Diet, general, 59
Digestive disturbances, 78
Diphtheria, antitoxin in blood, 68 as complication of scurvy, 217
Drying, effect on vitamines of, 66
Duodenum, pathology, 89
Dysentery, 59, 182
E
Economic status, 55
Eczema, 195
Edema, 178, 184, 196 hunger, 256 war, 256
Eggs, antiscorbutic value of, 168
Endocrine organs, gross pathology, 92 microscopic pathology, 104 extracts of, as preventive, 172 theory of vitamine action, 72
Epidemics, 2, 217
Epiphyses, separation of, 96, 181, 198
Etiology, 35 exciting factors in, 60
Excretion of vitamine, 77
Expeditions, scurvy in Arctic, 10
Experimental scurvy, 111 pathogenesis, 116 pathology, 122 symptoms, 135
Exudative diathesis, 59, 256
Eyeball, proptosis, 193
F
Familial tendency, 58
Fats, in diet, effect on scurvy, 59
Fever, 181, 216
Fœtus, effect of scorbutic diet on, 125
Food, excess of, 257
Foods, antiscorbutic, 143, 149 proprietary, 49
Fractures, 95
Frost-bite, 180
Fruit juices, 153
Fruits, fresh, 144
G
Generative organs, pathology, 104
Glands, endocrine, 72 changes in, 73, 92, 104
Glucose, blood content of, 244
Grapes, antiscorbutic value of, 158
Growth in scurvy, 213
Guinea-pig scurvy, 112, 114
Guinea-pig pathogenesis, 116 pathology, 122 relation to human, 115 symptoms, 135
Gums, 177, 181, 184 in infantile scurvy, 189 pathology of, 89, 100
H
Hair, changes in, 194
Heart, 200 gross pathology, 87 microscopic pathology, 99
Heat, effect on vitamine of, 65
Hemorrhages, 180, 189 as early symptoms, 178 distribution of, 84 gastric, 208 orbital, 193 subperiosteal, 95, 191 urinary, 204
History of scurvy, 1
Hog, effect of scorbutic diet on, 115
Hypophysis, 104
I
Infantile scurvy, history, 10 in artificially fed, 40 in breast-fed, 35 increase during World War, 21–22 relation to epidemic scurvy of adults, 15, 37 relation to rickets, 11, 110, 252 symptomatology, 183
Infection, as exciting factor, 60, 218 increased liability to, 68 effect on prognosis, 227
Intestines, gross pathology, 90 microscopic pathology, 100
Intravenous use of orange juice, 238
Irregularities in course of deficiency diseases, 78
J
Jaundice, 208
Joints, lesions of, 199
K
Kidneys, gross pathology, 91 microscopic pathology, 102
L
Latent scurvy, 179, 183, 187
Laxatives, failure to cure with, 28, 207
Lemon juice, antiscorbutic value of, 153, 234 dried, 155, 232 ration in British Navy, 9, 144
Lentils, value as antiscorbutic, 167, 231
Lice, theory of transmission of scurvy by, 30
Lime juice, antiscorbutic value of, 156 fallacy in regard to, 149 use in British Navy, 144
Liver, gross pathology, 91 microscopic pathology, 101
Lungs, gross pathology, 88 microscopic pathology, 99
Lymph-nodes, gross pathology, 92 microscopic pathology, 101
M
Malnutrition, general, 58
Malt soup, 50
Marrow, changes in, 107
Meat, fresh, 147, 168 salt, 146
“Mehlnaerschaden” of Czerny, 256
Metabolism in scurvy, 241–247
Milk, alkalized, 50 amount necessary to prevent scurvy, 49, 117, 150 boiled, 44, 65 condensed, 48 dried, 46, 66, 152 effect of industrial methods on, 43 evaporated, 45 pasteurized, 40, 65 home vs. commercial, 42 sterilized, 44 breast, amount necessary to prevent scurvy, 36, 39, 153 as cause of beriberi, 39 cows, antiscorbutic value of, 40, 152 goats, antiscorbutic value of, 153
Mineral metabolism in scurvy, 241–247
Monkey, scurvy in, 114, 127 pathology, 128
Muscles, pathology, 97
N
Nails, changes in, 194
Necropsy reports, 82
Nephritis, 205
Nerves, peripheral, in guinea-pig scurvy, 132 pathology, 105
Nervous system, effect of scurvy on, 202
Nutrition, general, in scurvy, 58, 59, 213
Nyctalopia, 182
O
Orange juice, antiscorbutic value of, 153, 234 “artificial,” 33 dried, 155 effect of alkalization of, 154 intravenous use of, 238 subcutaneous use of, 155 peel, antiscorbutic value of, 234
Osteogenesis imperfecta, 255
Osteomalacia, differentiation of, from scurvy, 255
Osteomyelitis, differentiation of, from scurvy, 222
Osteoporosis, differentiation of, from scurvy, 255
Osteotabes infantum, 109
P
Pains, as early symptom, 176
Pancreas, gross pathology, 91 microscopic pathology, 104
Pasteurized milk, 40
Pathogenesis of scurvy, theories of, 23
Pathology of scurvy in guinea-pig, 122 in man, gross, 83 microscopic, 96 in monkey, 128
Peas, antiscorbutic value of, 167, 231
Pellagra, 251
Phenols, excretion of, 245
Phosphate metabolism, 241–247
Pigeon, effect of scorbutic diet on, 114
Pneumonia, 202
Posture, characteristic, in guinea-pig, 136
Posture, characteristic, infant, 183
Potassium deficiency theory, 23 metabolism, 241–247
Potatoes, antiscorbutic value of, 6, 7, 146, 161, 235
Prevention of scurvy, 230
Prognosis, 225
Protein in diet, effect on scurvy, 59
Psychic element in scurvy, 57
Pulse, 181, 201
Pulses, germinated, 167, 231
Purpura, differential diagnosis, 221
Pyorrhœa, relation to lesion of gums, 181
R
Racial immunity, 56
Rats, effect of scorbutic diet on, 114, 115
Recurrent scurvy, 228
Respirations, 201
Retina, hemorrhages in, 105
Rheumatism, confusion with scurvy, 176, 220
Ribs, beading of, 197 pathology, 94 in guinea-pig, 129, 137
Rickets, relation of, to scurvy, 11, 110, 252
Rosary, 94, 197
S
Sauerkraut, antiscorbutic value of, 145
Season, effect on incidence, 54
Sex, effect on incidence, 56
Shaking, effect on antiscorbutic factor, 68
Ship beriberi, 250
Skin, pathology, 96
Spleen, gross pathology, 91 microscopic pathology, 102
Sprue, 256
Starvation, pathology of, 125
Stomach, gross pathology, 89 microscopic pathology, 100
Storage of vitamine in body, 74
Streptococcus in blood in scurvy, 134
Subacute form of scurvy, 184
Subcutaneous use of antiscorbutics, 155
Swede, antiscorbutic value of, 162, 235
Symptomatology, in adult, 176 in infant, 183
Syphilis, congenital, differential diagnosis, 222, 223
T
Teeth, in guinea-pig scurvy, 130, 137 in human scurvy, 177
Temperature, in guinea-pig scurvy, 141 in human scurvy, 181, 216
Thymus, pathology of, 104 use of gland in treatment, 172
Thyroid, pathology of, 104 use of gland in treatment, 172
Tomatoes, canned, antiscorbutic value of, 166, 231, 234 in U. S. Army ration, 231
Toxic theory of pathogenesis of scurvy, 25
Treatment of scurvy, 230 duration of, 237 non-dietetic, 239
U
Ultra-violet rays, effect on antiscorbutics, 67
Urea content of blood, 244 of tissues, 245
Urine in scurvy, 204–206
V
Vegetable juices, keeping qualities of, 161
Vegetables, antiscorbutic value of 144, 158 canned, 166 dehydrated, 163 effect of heat on, 159 fresh, 144, 158 ripeness of, effect on antiscorbutic value, 160
Vitamine, antiscorbutic, general discussion of, 62 action of, 68, 69 as antitoxin, 69 as catalytic agent, 70 as nutriment, 69 blood content of, 76 effect of heat on, 65 of ultra-violet ray on, 67 excretion of, 77
Vitamine, experimental evidence for, 62 fate in body, 74, 77 relation to water-soluble factor, 65, 67 relation to antineuritic vitamine, 67 resistance to chemical and physical processes, 64 storage in body of, 74 theory of scurvy, 32
W
Weight, loss of, 138, 213
“White line” of Fraenkel, 128, 198
World War, scurvy in, 15
X
X-ray in diagnosis of scurvy, 128, 192, 198
Y
Yeast, antiscorbutic value of, 171