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Microbe hunters

INDEX

Reading edition

Académie Française, 168

Academy of Medicine, 146, 147, 155, 157

Academy of Sciences, French, 25, 37, 67, 69, 73, 86, 149, 156, 157

Agramonte, A., 314

Alexander, servant of Th. Smith, 237, 239, 244

Alexander, the Great, 10

Alt, K., 354

Anthrax, 108-122;

Koch proves microbe cause of, 115

Antitoxin, diphtheria, 198-206;

first produced in America by Park, 201;

first tried on child, 201;

Roux announces cure by, 204, 205

Aquinas, St. Thomas, 341

Aristotle, 7, 27

Arrhenius, Svante, 56

Arsenic, changed by Ehrlich into magic bullet, 349-355

Atoxyl, Ehrlich’s experiments with, 347-349

Balard, Prof., 80, 81, 82, 83, 101

Baptist, John the, 91

Bassi, Laura, 28

Bastianelli, Dr., 304-305

Baumgarten, J., 220

Bayer, 205;

new magic bullet, 357, 358

Beer, diseases of, 97, 98

Beethoven, 55, 175, 222, 236, 250

Behring E., 184-206;

attempts chemical cure of diphtheria, 195;

discovers diphtheria antitoxin, 198-200;

other references, 220, 234, 338, 340

Bernard, Claude, 73, 101

Bertheim, A., 349, 354, 355

Bignami, 304-305

Bigo, M., 64, 69

Biot, the horse doctor, conversion of, by Pasteur, 163

Bloxam, Rosa, 281

Bonnet, Charles, 33, 47, 51

Bordet, J., 226-227

Bourrel, the horse doctor, 170

Boyle, Robert, 8, 19

Bruce, David, 252-277;

discovers microbe Malta fever, 254;

discovers trypanosome of nagana, 257;

discovers trypanosome of sleeping sickness, 264-266;

other references to, 235, 278, 346, 357;

proof tsetse fly carries nagana, 259-262;

proves tsetse fly carries sleeping sickness, 267-270;

surgeon at siege of Ladysmith, 262

Bruce, Lady, 252-277

Buffon, Count, 36, 42

Bux, Mahomed, 292, 293

Carroll, J., 311-333;

bitten by yellow fever mosquito, 318;

death of, 332

Carter, H. R., 316

Castellani, A., 264, 265

Chaillou, M., 203

Chamberland, M., work with Pasteur on anthrax and rabies, 147-182, 221

Chappuis, Charles, 60

Charles II, of England, 8

Child-bed Fever, Pasteur discovers cause of, 146

Cholera, Asiatic, 140-143;

Metchnikoff feeds microbes of, to self and assistants, 225

Cholera, of chickens, vaccine discovered for, 152-156

Claus, Prof., coins term “phagocyte” for Metchnikoff, 214

Cohn, F., 120, 122, 123

Cohnheim, J., 121, 122, 123, 128, 129

Cooke, Dr., 325, 328

Cromwell, 7

Darwin, 209, 233

Davaine, Dr. C., 109

Dean, Wm., bitten by yellow fever mosquito, 319

De Blowitz, 160, 162, 164

De Graaf, Regnier, 8

De la Rochette, Baron, 158

De la Tour, Cagniard, experiments on alcoholic fermentation, 60, 61, 65

De Saussure, 51, 54

Diphtheria, 184-206;

antitoxin discovered by Behring, 198-206;

microbe of, discovered, 185-187;

new method of prevention, 206;

toxin discovered by Roux, 189-193

Dostoevski, F., 207

Duclaux, E., 88, 89, 90, 94

Dumas, A., 87

Dumas, J. B., 60, 69, 73, 91, 92, 96, 156

Duns Scotus, 341

Edison, T. A., 287

Ehrenberg, 59

Ehrlich, Paul, 334-358;

announces cure human syphilis by salvarsan, 355;

attempts to find law of immunity, 339;

changes arsenic into magic bullet, 349-355;

cures syphilis of rabbits, 353;

discovers chemical cure for mal de caderas, 343-345;

discovers salvarsan (606), 350-356;

experiments with atoxyl, 347-349;

invents stain for tubercle microbe, 336;

other references to, 121, 194;

side-chain theory of immunity, 340;

worries over deaths from salvarsan, 356-357

Ellis, 52, 53, 54

Evolution, theory of organic, 78;

championed by Metchnikoff, 209

Faraday, Michael, 56, 64

Fehleisen, F., discovers microbe of erysipelas, 139

Fermentation, 60;

alcoholic, 60, 61, 71, 72, 73, 99, 100, 101, 102, 103;

lactic, 64, 65, 66, 67

Finlay, Carlos, 312, 313, 315, 316, 324

Fischer, Emil, 56

Flaubert, E., 228

Folk, L., 325, 327, 328

Force, vegetative, 37 et seq.

Fraatz, Emmy, 105

Frederick, the Great, 45

Frémy, M., 99, 100, 101

Gaffky, G., 129, 131, 132, 138, 141

Galileo, 4, 26, 27, 63, 163

Gamaléia, Dr., 217, 219, 224

Garrè, Dr., injects self with dangerous microbes, 139

Germ theory, battle of, 124

Gernez, M., 94, 95

Gibbons, Staff-Sergeant, 264

Goethe, W., 198, 222

Gorgas, W. C., 329, 330

Grancher, Dr., 179

Grassi, B., 298-310;

other references to, 235, 278, 279, 288, 315, 328;

practical demonstration malaria prevention, 307;

proves anopheles mosquito carries human malaria, 301-306

Grew, Nehemiah, 16

Guérin, J., 155, 156, 157

Guitéras, J., death of yellow fever patients in experiments, 330, 331

Hanging-drop, invention of, 113, 114

Harvey, William, 19

Hata, S., 352, 353

Hely-Hutchinson, Sir W., 255, 259, 262

Homer, 28, 55

Hoogvliet, 24

Hooke, Robert, 16

Immunity, 207-229;

due to phagocytes, 212-229;

Ehrlich attempts find law of, 339;

side-chain theory of, 340

Inquisition, Grand, 27

Institut Pasteur, 181, 187, 217, 218, 222

Invisible College, The, 7, 27

Jenner, E., 155

Jernegan, W., 325, 327, 328

Joly, M., 85, 86

Joseph II, of Austria, 49

Joubert, Prof., 147

Kadereit, 342, 344, 347, 348, 349, 356

Kagwa, Apolo, 268, 269, 270, 271, 272

Khan, Husein, as experimental animal for Ross, 288, 289

Kilborne, F. L., 237-251

Kissenger, Private, 322, 324, 326;

paralysis of, from yellow fever experiment, 333;

volunteers for mosquito bite, 323

Kitasato, S., 194, 338

Koch, Mrs., 106, 107, 110, 111, 300

Koch, Robert, 105-144;

dangerous experiments with tuberculosis, 136;

discovers microbe of cholera, 140-143;

experiments with anthrax, 108-128;

failure to cure tuberculosis with vaccine, 193, 194, 299;

first photographs microbes, 123;

invention of hanging-drop, 113, 114;

other references to, 24, 104, 145, 146, 147, 148, 166, 167, 168, 184, 185, 193, 194, 198, 200, 209, 211, 219, 234, 236, 237, 238, 250, 297, 299, 300, 304, 305, 314, 323, 335, 336, 338, 339;

proves microbe cause of anthrax, 115;

pure culture microbes discovered, 125, 126;

works on cause of tuberculosis, 128-138

Laveran, A., discovers malaria parasite, 281;

microbe of, demonstrated by Manson to Ross, 282;

other references to, 296, 342, 343

Lavoisier, A., 77

Lazear, J., 311-333;

bitten by yellow fever mosquito, 318;

died of yellow fever, 320

Lazear, Mrs. J., 312

Leeuwenhoek, Antony, 3-24;

an admirer of God, 12;

discovers human sperm, 19;

discovers microbes, 10, 11, 12;

discovers microbes in mouth, 17, 18;

experiments on origin of microbes, 13;

failure to find disease microbes, 22;

letters to Leibniz, 23;

letters to Royal Society, 9;

microbes in pepper water, 14;

other references to, 25, 26, 27, 28, 29, 44, 51, 61, 76, 77, 106, 108, 109, 111, 114, 128, 137, 138, 209, 228, 250, 334, 358

Leibniz, Gottfried W., 23

Leucart, R., 209

Leupold, 349

Le Verrier, 83

Liebig, J., 70, 73

Linnæus, 59

Lister, J., 100, 106, 182

Loeffler, F., discovers diphtheria microbe, 185-187;

foretells diphtheria toxin, 187;

other references to, 129, 131, 132, 138, 188, 189, 193, 331

Louvrier, the horse doctor, 149-150

Lutchman, 287

Maillot, M., 94

Maisonneuve, Dr., 231

Malaria, 278-310;

human, Grassi proves carried by anopheles mosquito, 301-306;

Manson’s theory mosquito carries, 283;

of birds carried by gray mosquito, 292-298;

prevention of practical demonstration of, by Grassi, 307

Mal de Caderas, 342-350;

Ehrlich cures by chemical, 343-345

Malta Fever, Bruce discovers microbe of, 254 ff.

Manson, Patrick, 282-298, 315;

announces Ross’s success at Edinburgh, 296, 297;

other references to, 235;

theory mosquitoes carry malaria, 283

Maria Theresa, 45

Marquardt, M., 348, 349, 356

Martin, M., 203

Meister, Joseph, vaccination of, for rabies, 179

Metchnikoff, E., 207-233;

acquires drug habit, 210;

assistants of, Blagovestchensky, Gheorgiewski, Hugenschmidt, Saltykoff, Sawtchenko, Wagner, 222, 223;

attempts suicide, 210;

attempts to prolong life, 228-233;

champions theory of evolution, 209;

comedy of Bulgarian bacilli, 232-233;

feeds cholera to self and assistants, 225;

founds phagocyte theory, 214-229;

nicknamed “God-is-not,” 207;

nicknamed “Mamma Metchnikoff,” 222;

nicknamed “Grandpa Christmas,” 228;

other references to, 187, 234;

starts circus at Pasteur Institute, 219-220;

syphilis, prevented by, 229-232

Metchnikoff, Ludmilla, 210, 211

Metchnikoff, Olga, 211, 212, 213, 214, 219, 220, 228, 233

Microbes, origin of, 13, 31;

Bruce discovers Malta fever, 254;

of diphtheria discovered by Loeffler, 185-187;

of Texas fever discovered by Th. Smith, 244;

of the air, 83, 84, 85, 86;

of tuberculosis discovered by Koch, 128-138;

pure culture discovered, 125, 126;

spontaneous generation of, 31, 32, 33, 38, 39, 40, 42, 43, 44, 78, 79, 86, 97

Molyneux, 16

Moran, John, 322, 327, 328;

volunteers for mosquito bite, 322, 323

Mosquito, gray carries bird malaria, 292-298;

anopheles carries human malaria, 301-306;

stegomyia carries yellow fever, 317-329

Mozart, W., 222, 280

Musset, M., 85, 86

Nabarro, 264

Nagana, 255-262;

trypanosome of, discovered by Bruce, 257;

tsetse fly carries, 259-262

Napoleon I, 55, 58

Napoleon III, 86

Needham, John T., experiments on spontaneous generation of microbes, 31 et seq.

Newton, Isaac, 8, 19, 27, 36, 63, 64, 250, 280

Nocard, M., 177

Pasteur, Louis, 57-104, 145-183;

alcoholic fermentation by yeast, 71, 72, 73, 99, 100, 101, 102, 103;

as a chemist, 61;

a violent patriot, 97;

boyhood experience with mad wolf, 57, 170;

death of, 181, 182;

disasters with anthrax vaccine, 165, 166;

discovers anthrax vaccine, 157-164;

discovers vaccine for chicken cholera, 152-156;

diseases of wines, 88, 89, 90;

experiments on spontaneous generation, 78, 79;

experiments with lactic fermentation, 64, 65, 66, 67;

experiments with microbes of the air, 83, 84, 85, 86;

inspirational letters to sisters, 59, 60;

last speech of, 182, 183;

other references to, 23, 24, 56, 105, 106, 107, 108, 109, 116, 121, 122, 123, 128, 132, 138, 139, 140, 141, 184, 187, 188, 193, 203, 211, 216, 218, 221, 228, 230, 234, 238, 250, 279, 312, 335, 340;

press agent for microbes, 63, 73, 77, 87, 90;

quarrel with Bernard, 101, 102, 103;

quarrels with Koch, 167, 168;

rabies vaccine discovered by, 169-181;

religious philosophy of, 79;

saves Russian peasants from rabies, 180, 181;

work on diseases of beer, 97;

work on diseases of silkworms, 91-97

Pasteurization, 90

Pasteur, Madame, 62, 63, 66, 68, 69, 72, 103, 151, 177, 182

Park, W. H., 201, 206

Peronçito, Dr., 152

Peter, the Great, 19

Pettenkofer, Max, swallows Koch’s cholera culture, 133, 134

Phagocytes, discovered by Metchnikoff, 214-229;

immunity due to, 212-229

Pidoux, Dr., theory of consumption, 108

Pompadour, Madame de, 27

Pouchet, M., 85, 86

Pouilly-le-Fort, famous experiment of, 159-164

Prolongation of life, attempted by Metchnikoff, 228-233

Prometheus, 163

Purboona, 292

Putrefaction, caused by microbes, 61

Rabelais, 166

Rabies, 169-181

Rayer, M., 109

Réaumur, René, 25

Redi, Francesco, 30, 35

Reed, W., 311-333;

death of, 333;

disproves infected clothing theory, 324, 325, 326;

fails to find microbe of yellow fever, 314, 315;

other references to, 235;

proves stegomyia mosquito carries yellow fever, 317-329

Renan, E., praises and admonishes Pasteur, 168, 169

Ross, Ronald, 278-298;

attempts proof Manson’s mosquito theory, 285-291, 297, 298;

discovers gray mosquito carries bird malaria, 292-298;

discovers malaria pigment in mosquito stomach, 289;

meets Patrick Manson, 282;

other references to, 309, 315

Rossignol, Dr., 158

Roux, E., 184-206;

announces cures by antitoxin at Buda-Pesth, 204, 205;

discovers diphtheria toxin, 189-193;

other references to, 69, 147-182, 217, 221, 229, 230, 231, 234;

syphilis prevented by, 229-232

Royal Society, 8, 25, 31, 32, 37;

as audience for Leeuwenhoek, 9, 13, 15, 17, 18, 19, 20, 22, 24;

confirm Leeuwenhoek’s discovery of microbes, 16;

elect Leeuwenhoek Fellow, 16

Russian peasants, saved by Pasteur, 180-181

Ruth, Babe, 237

Rutherford, Ernest, 56

Salmon, D. E., 237, 238, 242

Salvarsan (606), discovered by Ehrlich, 350-356;

deaths from, 356-357;

Ehrlich cures human syphilis with, 355;

Ehrlich cures syphilis of rabbits with, 353

Sand, George, 87

Schaudinn, F., discovers Spirocheta pallida, 351

Schwann, Th., experiments on putrefaction by microbes, 61, 76

Semmelweis, I., 145

Servetus, 4, 27

Shiga, I., 343, 344, 345

Silkworms, diseases of, 91-97

Sleeping sickness, 263-277;

Bruce proves tsetse fly carries, 267-270;

trypanosome of, discovered, 264-266

Smiles, Dr., 96

Smith, Th., 236-251;

discovers microbe of Texas fever, 244;

first experiments with Texas fever, 240;

other references to, 252, 255, 259, 270, 278, 299, 315;

proves ticks carry Texas fever, 246

Socrates, 166

Sola, Mr., experimental animal for Grassi, 303, 304, 328

Spallanzani, Lazzaro, 25-56;

accused of theft from museum, 49, 50, 51;

bladder of, preserved, 55;

experiments cruelly on self, 41;

experiments on multiplication of microbes, 53, 54;

experiments on spontaneous generation of microbes, 32, 33, 38, 39, 40, 42, 43, 44;

other references to, 24, 57, 61, 76, 77, 78, 79, 123, 128, 298;

proves microbes may live without air, 47;

studies on sex, 41

Spanish immigrants, Nos. 1, 2, 3, 4, 323, 324, 326, 332

Speyer, F., 347

Speyer, G., 347

Spirocheta pallida, discovered by Schaudinn, 351

Spontaneous generation, 28, 30, 31, 32, 33, 38, 39, 40, 42, 43, 44, 78, 79, 86, 97

Syphilis, 229-232;

human, cure of, by salvarsan, 355;

of rabbits cured by Ehrlich’s salvarsan, 353;

prevention of, by Roux and Metchnikoff, 229-232

Taute, injects self with nagana, 276

Texas fever, 238-251;

Th. Smith discovers microbe of, 244

Thuillier, L., killed in experiments with cholera, 141;

other references to, 161, 164, 165, 173

Tick, of Texas fever, 239-251;

Smith proves carries Texas fever, 246

Toxin, of diphtheria, 187-206;

discovered by Roux, 189-193;

foretold by Loeffler, 187

Trécul, M., 99

Trypan red, discovered by Ehrlich, 345;

fails to cure nagana and sleeping sickness, 346

Trypanosome, of nagana, 257-262;

of mal de caderas, 342-352;

of sleeping sickness discovered by Bruce, 264-266

Tsetse fly, carries nagana, 259-262;

Bruce proves, carries sleeping sickness, 267-270

Tuberculosis, 128-138;

Koch’s dangerous experiments with, 136;

Koch discovers microbe of, 128-138;

Koch’s failure to cure with vaccine, 193, 194, 299

Tulloch, killed by sleeping sickness, 272

Tyndall, John, disproof of spontaneous generation of microbes, 86

Vaccines, anthrax, 157-164;

chicken cholera, 152-156;

famous Pouilly-le-Fort experiment with, 159-164;

Koch’s failure with tuberculosis vaccine, 193, 194, 299;

rabies, 169-181;

smallpox, 155

Vallisnieri, 26

Vercel, J., 179

Villemin, J. A., 128

Virchow, R., 127, 137, 214

Volta, Canon, 49, 50, 51

Voltaire, 27, 41, 50

Vulpian, Dr., 179

Wahab, Abdul, 286

Waldeyer, W., 336

Wassermann, Reaction, principle discovered by Bordet, 226

Wines, diseases of, 88, 89, 90

Wood, Gen. Leonard, 313, 321

Yellow fever, 311-333;

disproof of infected clothing theory, 324-326;

failure of Reed to find microbe of, 314, 315;

Reed proves stegomyia mosquito carries, 317-329

Yersin, A., 188-192

Zanzarone, popular name for anopheles, 302-308

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