Note 2 — THE PATHOLOGY OF THE RESPIRATORY TRACT IN INFLUENZA

Early in the epidemic, Nicolle (106) and his co-workers described a filterable virus as the probable etiological agent in influenza. Several investigators have corroborated this work. Chief of these are: Gibson, Bowman, and Connor (46); Bradford, Bashford, and Wilson (16). The latter investigators independently isolated a filterable virus which may be cultivated by the Noguchi method and which, when inoculated into monkeys, produces a general reaction with specific respiratory lesions which, they think, are comparable to those of man in influenza. While these results must be confirmed, they offer greater promise than any other.