Note 227 — RESEARCH IV.

After writing this, I was present when an invalid, in whose foot the gout, after much wandering, had at last fixed, breathed 12 quarts of oxygene gas. While breathing, he eagerly pointed to the inflamed leg; and afterwards said he had felt in it a new sensation, somewhat like tension.—I never had seen oxygene respired where there was so much local inflammation.

June 18. After four quarts of oxygene with 6 of nitrous oxide and then 6 of nitrous oxide alone, violent itching of the wounds made by the leech; and redness and tumour.—Both had healed, and I did not expect to feel any thing more from them.—I tried this again with two doses of nitrous oxide—The yellow halo round one wound changed to crimson, and there was so much stinging and swelling that I feared suppuration.—Absorption here was rapid.