Note 66 — Chapter XXXII · MINERAL SPRINGS AND CHOICE OF SPA

Bain, of Harrogate, from his observations on a man with permanent cutaneous biliary fistula, found that the old sulphur spring of Harrogate increased both the quantity of bile and the bile solids. This, he thinks, may “fairly be taken as an index of the degree to which it stimulates the liver, and is, in fact, the most reliable indication of the value of a cholagogue.”