Note 247 — Chapter I

This is not merely a simple hypothesis, but a well-demonstrated fact. Hundreds of experiments by Boeck, Weill, Moebius, Charrin, Mairet, Bosc, Slosse, Laborde, Marie, etc., have established that among the deranged, during periods of excitation and afterwards, the urine is more toxic, i.e., more full of waste and excreted organic matter, while after the periods of depression it is less toxic, i.e., poorer in disaggregated matter, than among sane individuals, which proves that, among the former, the nutrition of the tissues is morbidly increased or retarded.