Note 1 — Preface.

Mr. Wilkie (the respectable resident apothecary at the Dispensary in this town) lately informed me that a woman, who resides in Sandgate, after losing three children from Small Pox, during the present prevalence of that disease, would yet neither use precautions nor remedial measures for the preservation of the remainder; although she daily witnessed the efficacy of Vaccination among her neighbours, even when performed during the existence of Small Pox itself in other members of the same families.