Note 63 — ADDENDA.

From the manner in which the author makes mention of James’s powder, it appears that it was administered in such large doses as produced vomiting. It should have been given in small quantities, so as to have acted as a diaphoretic, both alone, and in conjunction with opiates. Perhaps, however, it may be objected that this and other antimonials, in small doses, repeated at intervals of three or four hours, are too tardy in their operation for a disease so rapid in its progress? In larger doses they would be apt to purge. Thus there seems to be little encouragement for administering them in any way, in cases of the plague. Tr.